Why novel dsRNA molecules in GM food are of little to no concern

franknrice x
Biofortified's mascot, Frankenfoode. via Biofortified

Recently, concerns were raised about the potential risks of dietary double stranded RNA (dsRNA) and microRNA (miRNA) molecules silencing human genes, after research by Zhang et al. showed the presence of plant miRNA in human blood plasma, as well as providing evidence that this plant miRNA enters the system by dietary uptake in mice. The group then demonstrated that this plant miRNA could silence genes in the mice, leading other researchers to separately raise concerns that diets consisting of genetically modified organisms could lead to the uptake of novel dsRNA molecules that could silence human genes. Uptake of dsRNA or miRNA at levels that would lead to gene silencing would therefore be an important consideration in food safety, including the safety of GMOs.

However, recent studies have failed to reproduce these results and questioned the likelihood of dietary uptake of plant miRNA molecules in mammals.

Read the full, original story here: Why novel dsRNA molecules in GM food are of little to no concern

Additional Resources:

 

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend