Autism risk from antipsychotics during pregnancy misreported, hyped by media

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis.

The alarm has been sounded: Antidepressants cause autism! Or so one could easily think based on a new study in JAMA Pediatrics. Four researchers in Quebec conclude that “the use of antidepressants, specifically selective serotonin reuptake inhibitors [SSRIs], during the second and/or third trimester increases the risk of [autism spectrum disorder] in children.” In a ResearchGate interview, study senior author and perinatal pharmacoepidemiologist Anick Bérard of the Université de Montréal and the CHU Sainte-Justine Research Centre firmly advocated avoiding antidepressant use during pregnancy: “Depression needs to be treated during pregnancy but with something other than antidepressants in the majority of cases. The risk/benefit ratio is clearly leaning towards no use.”

If true, this could be a discovery with implications for the much-debated “autism epidemic” and require serious reconsideration of depression treatment for pregnant women. Has a missing link been found?

Study co-author Bérard, it turns out, has been criticized by a federal judge for cherry-picking results to link antidepressants to birth defects. The press should treat such studies with skepticism rather than leading with their findings. Sober pieces inScience, Wired, and NPR rightly questioned whether the study was significant and whether Bérard’s advocacy for stopping antidepressant usage during pregnancy was justified. In particular, Emily Underwood in Science wisely led off by writing “Many epidemiologists and psychiatrists say the study, published today in JAMA Pediatrics, is flawed and will cause unnecessary panic.”

Read full, original post: Another Misguided Panic About Autism

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