Genetic variants play a key role in how individuals metabolize coffee. Some can drink coffee before bed and go right to sleep, while others a wired after just a single cup.
Studying how genes impact coffee consumption habits is nothing new. A 2014 study identified genetic variants that are associated with coffee consumption behavior…another study published earlier this year also found that the amount of coffee a person drinks was also due to a genetic variation (or lack thereof).
…similar methodologies have now been used to study metabolites in the blood – or chemicals found in one’s blood after consuming caffeine.
The new study, Marilyn Cornelis, assistant professor in the department of Preventive Medicine at Northwestern University Feinberg School of Medicine, found the same variants identified in 2014, as well as an additional variant.
Cornelis’ research also found genetic variants were linked to lower levels of caffeine metabolites, which imply faster caffeine metabolism, are the same variants previously linked to higher coffee consumption….[and] many of the genes found to metabolize caffeine also coded for proteins that function in the metabolism of other clinically important drugs, such as those that treat insomnia, Parkinson’s Disease, hypertension and more.
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