Abby Solomon suffers from a one-in-a-billion genetic syndrome: After just about an hour without food, she begins to starve…[But as soon as she] nibbles a few bites, she feels full, so she ends up consuming very few calories. At 5 feet 10 inches tall, she weighs 99 pounds.
Now 21 years old, she is one of the few people in the world to survive into adulthood with neonatal progeroid syndrome, a condition that results from damage to the FBN1 gene. This mutation mangles noses and eyes and destroys the layer of fat under the skin so that even teenagers look middle-aged.[However,] her painful body may hold the clues to a lifesaving treatment for millions of people with obesity and diabetes…By observing her, scientists can see how a hormone deficiency affects a living person, from her thoughts to her liver function.
Dr. Chopra believes asprosin is an unusually promising hormone for drug development “because we have a living, breathing human who has the natural depletion of this hormone in her blood.”
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: The Thin Gene