‘Supercharged’ T-cells could treat autoimmune disorders

arthritis
Rheumatoid arthritis

Researchers in both academia and industry are turning to immune-suppressing cells to clamp down on autoimmune disorders, and the effort is building to a fever pitch.

T cells are often thought of as key foot soldiers in the immune system’s battle against foreign invaders. But there are many kinds of T cell, each armed with a different set of skills.

People with disorders caused by an autoimmune attack often also have reduced levels of regulatory T-cell activity, leading scientists to suspect that bolstering such cells could reduce the immune system’s attack on the body.

To boost these cells, many researchers […] are turning to a molecule called interleukin-2 (IL-2). High doses of IL-2 stimulate the ‘effector’ T cells that attack invaders.

There are still concerns about how specific the IL-2 treatment can be — any potential stimulation of effector T-cell responses in a patient who is already undergoing an autoimmune attack could be dangerous. “It’s a robust field, but a challenging field,” says Jeffrey Bluestone, an immunologist at the University of California […] “It’s still unclear that you can get a regulatory T-specific response without any other effects.”

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: Drug companies flock to supercharged T-cells in fight against autoimmune disease

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend