The GLP is committed to full transparency. Download and review our 2019 Annual Report

Viewpoint: Moving forward with human gene editing requires scientists to ‘educate, engage, and empower’ the public, policymakers

, | | November 8, 2019

This article or excerpt is included in the GLP’s daily curated selection of ideologically diverse news, opinion and analysis of biotechnology innovation.

Researchers have long struggled to draw a line around ethical genome editing. While modifications to somatic cells only affect a single individual, engineering germline cells (such as eggs, sperm, or embryos) ensures that a specific trait will be transmitted to future generations. Although many scientists contend that somatic genome editing could dramatically advance human health, the ethics of germline modification remain controversial.

Worries of the ethical implications of deliberately editing out entire traits and concerns over the destruction of human embryos for research purposes have stigmatized germline genome editing. Moreover, the threat of unintended consequences and “off-target” effects emphasize the risk posed by CRISPR-driven research on germline cells and human embryos. But over the past decade, advances in research methods and laboratory techniques and an increased understanding of the human genome have attracted greater attention to the therapeutic potential of CRISPR gene editing.

Related article:  Geneticist Alison Van Eenennaam explains how the CRISPR gene editing 'revolution' can improve our food

Since a robust understanding of the science behind CRISPR must still be developed, the most important responsibility that scientists have is to educate, engage, and empower the public and policymakers. Only then will all stakeholders be able to take part in discussions about the ethics of heritable genome editing.

Read full, original post: Is there a responsible way forward for gene editing?

News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.

Send this to a friend