Coronavirus pill? Oral antiviral medication shows promise, slated for human tests

this orally taken coronavirus drug saw success in animal tests md

An oral medicine was able to hinder the coronavirus behind COVID-19 as it attempted to replicate itself in human lung cells in test tubes, scientists reported [April 6]. It also hampered closely related coronaviruses from reproducing in mice for several days and improved their lung functions.

The drug, called EIDD-2801, interferes with a key mechanism that allows the SARS-CoV-2 virus to reproduce in high numbers and cause infections, the researchers explained in the journal Science Translational Medicine. [I]f the effect is similar in people, the drug would be the first pill available to help with the COVID-19 pandemic, which has resulted in more than 1.3 million cases and about 76,400 deaths worldwide. An oral medication would be a boon, because it would be easier to give to more people than an intravenous injection.

Related article:  First gene-edited CRISPR COVID-19 mouse created; Opens door to study infections and develop therapies

… A company that has licensed the drug, Ridgeback Biotherapeutics, has just been granted permission from the U.S. Food and Drug Administration to begin 10 patient trials of the antiviral pill in the next few months.

In addition to planning clinical trials in the U.S., Ridgeback has also asked U.K. authorities to start tests there as well. “We’ve done three to four years of development work in just the past three to four weeks in response to the new pandemic,” [said Wayne Holman, Ridgeback co-founder.]

Read the original post

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Infographic: What are mRNA COVID-19 vaccines and how do they work?

Infographic: What are mRNA COVID-19 vaccines and how do they work?

As of 1 December 2020, thirteen vaccines have reached the final stage of testing: where they are being given to ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
glp menu logo outlined

Newsletter Subscription

Optional. Mail on special occasions.
Send this to a friend