The Great migrations in the US in the first half of the 20th century show up in our genes

sep c migration
Credit: MPI/Getty Images
[Software engineer Chengzhen Dai] and his advisor, designer and engineer Carlo Ratti, teamed up with population geneticist Alicia Martin of the Broad Institute and other colleagues to test their hypothesis [that geography has played a major role in how ancestry and admixture occurs] using data from National Geographic’s Genographic Project, a now-discontinued effort to sequence genomes from around the world to track migration patterns.

Focusing on the genomes of 32,589 participants who’d provided a postal code, the team compared single-nucleotide polymorphisms (SNPs) in those genomes with the SNPs present in reference genomes curated by the 1000 Genomes Project, a UK-based initiative that compiled genomic data on 2,504 people representing 26 populations worldwide.

Follow the latest news and policy debates on agricultural biotech and biomedicine? Subscribe to our newsletter.

As Dai and his colleagues had predicted, genetic relatedness turned out to correlate with geography, although the drivers of that relationship seemed to vary among demographic groups. Among African-Americans, for example, there was broad genetic relatedness among people living along the East Coast, from Florida to Maine, indicating frequent migration within that area. But the researchers also found evidence of reduced migration through certain regions. Overall, the authors write, the patterns they found are consistent with movement trends during the Great Migration of the early- to mid-20th century, in which millions of African-Americans left the South for cities in other areas of the country.

Related article:  Fear and anxiety may not be as separate as we have come to believe

Read the original post

Outbreak Daily Digest
Biotech Facts & Fallacies
Genetics Unzipped
Infographic: How dangerous COVID mutant strains develop

Infographic: How dangerous COVID mutant strains develop

Sometime in 2019, probably in China, SARS CoV-2 figured out a way to interact with a specific "spike" on the ...

Philip Njemanze: Leading African anti-GMO activist claims Gates Foundation destroying Nigeria

Nigerian anti-GMO activist, physician, and inventor pushes anti-gay and anti-GMO ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
glp menu logo outlined

Newsletter Subscription

Optional. Mail on special occasions.
Send this to a friend