Klotho: Is prescribing a drug to supercharge the brain a good idea?

merlin f e ff ee bd bd videolarge

One of the most intriguing molecules out there is called Klotho. Identified in 1997, it’s named for the Fate of ancient Greek mythology who spun the thread the life. Mice that have a severely limited amount of Klotho in their body age rapidly and die prematurely. On the other hand, mice that carry more Klotho than normal live longer lives and appear to be resistant in some ways to aging.

Last April, an article appeared in the New York Times, titled “One Day There May Be a Drug to Turbocharge the Brain. Who Should Get it?” Massive contributor and neuroscientist Yewande Pearse and editor Dan Samorodnitsky [discussed] Klotho — what it is, what it does, and whether prescribing a drug to supercharge the brain is a good idea.

[Yewande Pearse:] I think we should be very careful about altering something that does indeed have so many actions and effects. Once Klotho is secreted, it enters the blood stream and goes everywhere, but by taking Klotho orally, I am not sure how can we ensure Klotho is going to the right places in the right quantities in a way that is effective and safe.

Related article:  The genetics of poop and how it can help our health – and threaten our privacy
Follow the latest news and policy debates on agricultural biotech and biomedicine? Subscribe to our newsletter.

As a neuroscience researcher, my priority is safety and the ethics around that. If we can ensure that taking “extra” Klotho is safe and effective then, I don’t think we should be worried [about the ethics of taking it].

Read the original post

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Genetics Unzipped
Infographic: How dangerous COVID mutant strains develop

Infographic: How dangerous COVID mutant strains develop

Sometime in 2019, probably in China, SARS CoV-2 figured out a way to interact with a specific "spike" on the ...
Untitled

Philip Njemanze: Leading African anti-GMO activist claims Gates Foundation destroying Nigeria

Nigerian anti-GMO activist, physician, and inventor pushes anti-gay and anti-GMO ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
glp menu logo outlined

Newsletter Subscription

Optional. Mail on special occasions.
Send this to a friend