Human kidneys grown in pig embryos? Xenotransplantation strides into the future

Human kidneys grown in pig embryos? Xenotransplantation strides into the future

Amanda Heidt | 
Scientists introduced human stem cells into pig embryos engineered to lack a kidney, stem cells then differentiated and grew into ...
Could a cup of yogurt replace a colonoscopy? Engineered bacteria can detect and deliver treatment for some pre-cancerous colorectal polyps

Could a cup of yogurt replace a colonoscopy? Engineered bacteria can detect and deliver treatment for some pre-cancerous colorectal polyps

Angus Chen | 
A cup of yogurt — containing engineered bacteria that can detect and deliver a treatment for colorectal polyps or cancer ...
Xenotransplantation breakthrough: Brain dead patients Two brain-dead patients with genetically altered transplanted pig kidneys are still functioning

Genetically-modified pig kidney transplants into live patients may be next in wake of successful transplants into brain-dead patients

Roni Caryn Rabin | 
Researchers at the University of Alabama at Birmingham published a peer-reviewed study showing that modified pig kidneys performed complex life-sustaining ...
mRNA technology revolution: Battling sickle cell, aging and other tough-to-tackle diseases will soon be easier and cheaper

mRNA technology revolution: Battling sickle cell, aging and other tough-to-tackle diseases will soon be easier and cheaper

Michael Le Page | 
A technique for delivering mRNAs to blood stem cells should enable better and cheaper treatments for conditions from sickle cell ...
'We believe we have developed the first technology to design an organism that can’t be infected by any known virus'

Viewpoint: ‘We believe we have developed the first organism that can’t be infected by any known virus’

David Zarley | 
Researchers at George Chuch’s Harvard lab have genetically engineered a bacteria, E. coli, to be totally immune to viruses ...
Next up on the gene-edited pig heart transplant list? Babies

Next up on the gene-edited pig heart transplant list? Babies

Jessica Hamzelou | 
The company eGenesis has started transplanting gene-edited pigs’ hearts into infant baboons—and humans may be next ...
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Inhalable CRISPR-based treatment for cystic fibrosis, lung disease on the horizon

Anne Trafton | 
A nanoparticle developed by MIT chemical engineer Daniel Anderson and colleagues can deliver messenger RNA encoding CRISPR gene-editing proteins to ...
group of dead adult mosquitoes scattered uniformly throught the field of view during a vector control study

Unleashing the swarm: Battling the global mosquito menace and defending public health

Jon Entine, Sam Moxon | 
The Greek Ministry of Health has issued a stark warning: rapidly multiplying, stealthily infiltrating and carrying a deadly payload of ...
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How does chronic stress worsen gut inflammation and cause bowel diseases?

Saima Sidik | 
Signals originating in the brain make their way to gut nerve cells, leading to a release of inflammatory chemicals ...
Forgotten by science: Four decades ago, medical researchers launched studies on rural Colombian families with fatal Huntington’s disease. They are just now following up

Forgotten by science: Four decades ago, medical researchers launched studies on rural Colombian families with fatal Huntington’s disease. They are just now following up

Jennie Smith | 
Huntington’s is a hereditary neurodegenerative disease caused by excess repetitions of three building blocks of DNA ...
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RSV vaccine breakthrough prevents respiratory infections that pose serious hazards to older adults

Henry Miller | 
It is not every day that drug development results in a breakthrough with the potential to eliminate an often serious ...
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Race for a cure: ‘After decades of neglect, stigma and underfunding, sickle cell is getting the red carpet treatment in science.’ Here’s what that means

Carolyn Johnson | 
The first gene therapies for sickle cell, including one based on the buzzy, Nobel Prize-winning technique called CRISPR ...
What we know about the debilitating persistence of long COVID?

What do we know about the debilitating persistence of long COVID?

Dave Davies | 
Millions of Americans who contracted the disease continue to suffer from symptoms associated with long COVID ...
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Viewpoint: ‘Imposing impoverishment’ — How European leadership has failed by promoting ideological solutions to sustainability challenges in farming

David Zaruk | 
It is hard to find anyone with anything positive to say about 2022: economic, social, ethical, political, geopolitical success stories ...
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Personalized pancreatic cancer vaccine that uses mRNA technology to fight tumors show promise

Brenda Goodman | 
Pancreatic cancer is one of the most lethal malignancies, fatal in 88% of patients. It is also one of the ...
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Podcast: UK baby born from three ‘parents’ stirs hope and concerns

Darren Griffin, Madeleine Finlay | 
The pioneering IVF procedure known as mitochondrial donation therapy (MDT) could prevent children from being born with devastating mitochondrial diseases ...
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GLP podcast & video: Harmful chemicals in fish? How your genes affect the drugs you take; 3 pesticide myths debunked

Cameron English, Liza Dunn | 
Are you getting a potentially toxic dose of chemicals every time you eat fish? A new study has raised this ...
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GLP podcast and video: ChatGPT more empathetic than doctors? How ideology corrupts science; Testing drugs on mini-organs, not animals

Cameron English, Liza Dunn | 
Is ChatGPT more empathetic than your doctor? A recent study seems to suggest so. An emerging consensus of scientists is ...
Precision medicine and pharmacogenetics: Here's why certain drugs work better for some people than others

Precision medicine and pharmacogenetics: Here’s why certain drugs work better for some people than others

Catherine Ho | 
UCSF soon will start a genetic testing program for patients, believed to be the first of its kind in California ...
Pharmacy shelves are bare of many critical drugs. Reciprocity between the US and other countries could help address that 

Pharmacy shelves are bare of many critical drugs. Reciprocity between the US and other countries could help address that 

Henry Miller | 
Dr. Deborah Greenhouse, a pediatrician in South Carolina, tweeted on February 1,  OK pediatricians, I'm starting a new contest: Who ...
Pregnancy and COVID: Babies exposed to mild coronavirus cases in utero undergo normal brain development

Pregnancy and COVID: Babies exposed to mild coronavirus cases in utero undergo normal brain development

Stephanie Soucheray | 
The infants of mothers who had asymptomatic or mild COVID-19 infections during pregnancy showed no neurodevelopment delays compared to peers with no ...
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Vaccines for heart disease and cancer? Moderna says immunization against the world’s deadliest diseases could be here by 2030

Lisa O’Mary | 
Vaccines for the world’s most deadly diseases, like cancer and heart disease, will likely be ready by 2030 and could ...
Better than obesity drugs? Here’s how this flowering shrub can naturally block fat absorption

Better than obesity drugs? Here’s how this flowering shrub can naturally block fat absorption

RMIT, Shu Shu Zheng | 
Antioxidants in the roselle plant have anti-obesity properties that could help in food alternatives to current weight management medications, according ...
Challenging taboos: How the genetics of race impact breast cancer

Challenging taboos: How genetics of ‘race’ impact breast cancer treatments

Angus Chen | 
Cinicians know the odds tend to be stacked against Black breast cancer patients. They have more dangerous and aggressive subtypes ...
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Video: From scorpion-venom cabbage to human breast milk from cows, here are 9 of the most unique genetically-engineered products likely to come to market

In this video are some of the strangest genetically modified products. We know that these products aren’t handcrafted by Mother ...
Psychedelics pioneer Roland Griffiths learns how to die

Psychedelics pioneer Roland Griffiths learns how to die

David Marchese | 
As the founding director of the Johns Hopkins Center for Psychedelic and Consciousness Research, Dr. Roland Griffiths has been a ...
Why did Ellie in the Last of Us not succumb to Cordy, the zombie virus? Stem cells might explain it, and that could yield real-life vaccines

Why did Ellie in the Last of Us not succumb to Cordy, the zombie virus? Stem cells might explain it, and that could yield real-life vaccines

Carly Lewis, Ricki Lewis | 
It’s unsettling to watch The Last of Us, in which parasitic fungi turn humanity into flesh-eating zombies, just as the ...
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