In an unprecedented move hoping to quell criticism, FDA releases documents detailing messy internal debate over Biogen's dementia drug Aduhelm

In an unprecedented move hoping to quell criticism, FDA releases documents detailing messy internal debate over Biogen’s dementia drug Aduhelm

[A] series of documents [were released June 22] by the FDA to explain its decision to use a truncated pathway, ...
Tough time recovering from jet lag? US government-university partnership developing implantable ‘living pharmacy’ to control our circadian clocks

Tough time recovering from jet lag? US government-university partnership developing implantable ‘living pharmacy’ to control our circadian clocks

A Northwestern University-led team of researchers has signed a cooperative agreement with the Defense Advanced Research Projects Agency (DARPA) to develop a ...
Beyond dopamine: The science behind how and why the brain works to make us happy

Beyond dopamine: The science behind how and why the brain works to make us happy

[Dopamine is] one of the many, many chemicals (aka neurotransmitters) found in the human brain, where it has many functions ...
6 eyewitnesses identified a Texas man as a murderer. It took forensic DNA to prove they were wrong — sparking conversation on how to prevent ‘lineup bias’

6 eyewitnesses identified a Texas man as a murderer. It took forensic DNA to prove they were wrong — sparking conversation on how to prevent ‘lineup bias’

On the strength of six eyewitnesses’ lineup identifications, Lydell Grant was sentenced to life in prison in 2012 for the murder ...
Brainless hydras can tell us a lot about the significance of sleep

Brainless hydras can tell us a lot about the significance of sleep

It does not have a brain, or even much of a nervous system.  And yet, new research shows, it sleeps ...
‘Mixed-handers’ make up less than 1% of the world’s population — except in the NBA where 1 in 12 stars play and write with different hands. What’s going on?

‘Mixed-handers’ make up less than 1% of the world’s population — except in the NBA where 1 in 12 stars play and write with different hands. What’s going on?

LeBron James writes with his left hand, eats with his left hand and uses his dominant left hand for almost ...
Is machine-based mind control on the near horizon?

Is machine-based mind control on the near horizon?

Laser beams, ultrasound, electromagnetic pulses, mild alternating and direct current stimulation and other methods now allow access to, and manipulation ...
Symptoms tell us only so much about the roots of depression. Here’s a new set of tools that could unlock the physiology of the brain, leading to cutting-edge therapies

Symptoms tell us only so much about the roots of depression. Here’s a new set of tools that could unlock the physiology of the brain, leading to cutting-edge therapies

[W]hat actually causes depression? Is there a tiny but important area of the brain that researchers should focus on? And ...
Video: An extra thumb? Here’s a real life demonstration of how it could change how we live

Video: An extra thumb? Here’s a real life demonstration of how it could change how we live

A thorough research carried out by the University College London (UCL) in collaboration with Dani Clode Design, wanted to see ...
FDA approves first Alzheimer’s drug in nearly 20 years — but some experts say there’s not enough evidence it actually works

FDA approves first Alzheimer’s drug in nearly 20 years — but some experts say there’s not enough evidence it actually works

[On June 7, the FDA approved Alzheimer’s drug aducanumab,] the first drug cleared that is designed to alter the course ...
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Viewpoint: Zombie pseudoscience — Evolution and intelligence studies are still shadowed by a focus on brain size

Phrenology is the detailed study of cranial sizes and shapes as a proxy for brain size and shape... Phrenology has ...
‘Magic mushroom’ migraine relief? Single dose of psilocybin shows significant impact in reducing intractable headaches

‘Magic mushroom’ migraine relief? Single dose of psilocybin shows significant impact in reducing intractable headaches

Migraine treatments can be either preventive or abortive, and they range from prescription drugs, to over-the-counter medications like Advil Migraine, ...
Do people with artificial limbs come to see their prostheses as a natural part of the body — or just a tool?

Do people with artificial limbs come to see their prostheses as a natural part of the body — or just a tool?

[How do] humans’ wealth of sensory inputs—including the touch and visual perception involved in manipulating a tool—modify the sense of ...
Brain scans show how LSD works to unlock the brain and treat depression

Brain scans show how LSD works to unlock the brain and treat depression

By comparing scans of the brain on LSD versus placebo… researchers found that the drug reduced the amount of energy ...
Evolution of creativity: An emerging theory of why Neanderthals succumbed to more ‘advanced’ Homo sapiens

Evolution of creativity: An emerging theory of why Neanderthals succumbed to more ‘advanced’ Homo sapiens

Theories regarding the extinction of the Neanderthals range from climate change or the homo sapiens outpacing them in terms of ...
Can you stall Alzheimer’s and memory loss? Nutrient-dense Mediterranean diet could help, mounting evidence suggests

Can you stall Alzheimer’s and memory loss? Nutrient-dense Mediterranean diet could help, mounting evidence suggests

Meals inspired by traditional foods from the sunny Mediterranean, a new study found, may lower your risk for dementia by ...
Are human brains the evolved pinnacle of problem-solving evolution? The reality may be more mundane

Are human brains the evolved pinnacle of problem-solving evolution? The reality may be more mundane

People often assume that evolution has progressed in an upward trajectory, from simple organisms to more complex ones. Because humans ...
‘Mindwriting’: Paralyzed clinical trial patient with brain implant able to ‘type’ words by thinking about writing by hand

‘Mindwriting’: Paralyzed clinical trial patient with brain implant able to ‘type’ words by thinking about writing by hand

Call it “mindwriting.” The combination of mental effort and state-of-the-art technology have allowed a man with spinal injury and immobilized ...
Reach for ice cream when you’re feeling down? Sugar-laden, high-fat foods are comforting, but least likely to benefit mental health

Reach for ice cream when you’re feeling down? Sugar-laden, high-fat foods are comforting, but least likely to benefit mental health

[O]ver the years, a growing body of research has provided intriguing hints about the ways in which foods may affect ...
Were self awareness and the ability to plan what set us apart from Neanderthals?

Were self awareness and the ability to plan what set us apart from Neanderthals?

We bear a trace of Neandertal legacy in our genome, a bequest from ancestral interbreeding. But some experts argue that, ...
‘Game-changing failure’: Trials of two Huntington’s disease-fighting gene therapy drugs halted, in ‘crushing blow’ to sufferers

‘Game-changing failure’: Trials of two Huntington’s disease-fighting gene therapy drugs halted, in ‘crushing blow’ to sufferers

Researchers had hoped that [a new treatment in trials] —known as antisense oligonucleotides (ASOs)—would be a game changer for [Huntington’s ...
BMI and anorexia: We can now predict which children are most likely to develop an eating disorder

BMI and anorexia: We can now predict which children are most likely to develop an eating disorder

Could there be a way to tell years in advance which girls are more likely to develop eating disorders?  New ...
Mapping overthinking: Athletes who ‘choke’ under pressure activate areas of the brain involved in long-term thinking

Mapping overthinking: Athletes who ‘choke’ under pressure activate areas of the brain involved in long-term thinking

Are penalty shots a soccer player’s dream or nightmare? Penalties can go either way, which makes them exciting to watch, ...
‘The most terrifying thing’: For an unlucky few, even mild COVID can lead to psychosis. We still don’t know why

‘The most terrifying thing’: For an unlucky few, even mild COVID can lead to psychosis. We still don’t know why

[I]n mid-December, after a mild case of Covid-19, [49-year-old former marine Ivan Agerton] was seized by a kind of psychosis ...
Dunbar’s number: Is the human brain’s capacity for friends really limited to 150?

Dunbar’s number: Is the human brain’s capacity for friends really limited to 150?

It's called Dunbar's number: an influential and oft-repeated theory suggesting the average person can only maintain about 150 stable social ...
Viewpoint: ‘Dump Dimorphism’ — Challenging orthodoxy, neuroscientists claim 30 years of studies show ‘no meaningful male-female brain differences’

Viewpoint: ‘Dump Dimorphism’ — Challenging orthodoxy, neuroscientists claim 30 years of studies show ‘no meaningful male-female brain differences’

Everyone knows the difference between male and female brains. One is chatty and a little nervous, but never forgets and takes ...
Brain size v body size: ‘There is no single evolutionary path to a bigger brain’

Brain size v body size: ‘There is no single evolutionary path to a bigger brain’

Over nearly 200 million years of mammal evolution… researchers have shown that brain size is actually secondary to body size ...
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