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Gene therapy for Alzheimer’s? Biotech startup suggests new approach, using dementia ‘off switch’

What if there were a single mechanism in the brain that, when faulty, leads to all kinds of dementias? And ...
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Rethinking the brain’s reward system—and what creates human intelligence

In a paper published in Nature ... DeepMind, Alphabet’s AI subsidiary, has once again used lessons from reinforcement learning to ...
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Sperm test could predict odds of fathering child with autism

Some men who have an autistic child carry mutations linked to the condition only in their sperm, according to a ...
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Can we use the brain’s ‘biochemical changes’ to predict—and prevent— suicide?

No field of scientific inquiry can single-handedly untangle a phenomenon as complex as suicide. But [Kees] van Heeringen and many ...
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Brain building block glutamate could be key to treating Alzheimer’s, schizophrenia, depression

Glutamate is often called the “major excitatory neurotransmitter” within the brain. It is the brain’s “go” signal. [Neuroscientist David] Baker ...
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Why we’re seeing more cases of autoimmune disorder PANDAS—if it even exists

In 1998, Susan Swedo, then a pediatrician at the U.S. National Institutes of Health (NIH), first proposed PANDAS to explain ...
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The psychology of risk: ‘Psychopathic traits regularly found in successful people’

One problem with research on psychopathy is that it largely only deals with criminals. [Psychiatrist Randi] Rosenqvist believes it would ...
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‘Mini-computers’ found in our neurons could be key to developing more powerful AI networks

With just their input cables, human neurons can perform difficult logic calculations previously only seen in entire neural networks. To ...
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Always late? Psychologist explains complex reasons behind a trait so annoying to others

Punctual people may believe that late people are passive-aggressive and that their time is more valuable than those who wait for ...
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Autism may share genetic links to schizophrenia, bipolar disorder, depression and other psychiatric disorders

Some of the inherited variants implicated in autism also increase the odds of other conditions, including schizophrenia, bipolar disorder, depression ...
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‘Strange’ twist for viral version of Parkinson’s: It may take decades for disease symptoms to appear

In recent years, a mysterious surge of a Parkinson’s-like disorder spread around the world, causing an estimated 10-15% of the ten million worldwide ...
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Growing tiny brains for research: Should we ‘frantically panic’ that something might go awry?

As mini-brains become more advanced, some researchers are worried they'll develop consciousness ...
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Sex-linked mutations point to need for closer look at causes of autism in women, study suggests

Autism may stem from a different — and larger — set of genetic mutations in women than it does in ...
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Some patients in vegetative states have functioning minds. Keeping them alive may amount to ‘torture’

[Researchers] have convincingly demonstrated that a subset of individuals in persistent vegetative states have meaningfully functioning minds — even as ...
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Can we add ‘cooking’ to the list of things that drove human evolution?

Theories about the driving forces of evolutionary differentiation that separated us from our ape relatives are not lacking. Toolmaking, predisposition to ...
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Age isn’t the thing that saps our memories: ‘Experiencing new things is the best way to keep the mind young’

Twenty-year-olds don’t think, “Oh dear, this must be early-onset Alzheimer’s.” They think, “I’ve got a lot on my plate right ...
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Are we getting closer to understanding how our brains make memories?

How do memories work? That has been a burning question for over a century, since Richard Semon introduced the term ...
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Gene therapy offers hope for untreatable CTE brain disorder

[Researchers from Weill Cornell Medical College] published a new study (“Anti-Phospho-Tau Gene Therapy for Chronic Traumatic Encephalopathy”) in Human Gene Therapy that ...
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Podcast: Recovering memories through song: Could this be a ‘standard of care’ for dementia patients?

PATTI NEIGHMOND, BYLINE: The connection between music and memory was a life-changing experience for Nancy Gustafson, a retired opera singer ...
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‘Chicken or the egg’? We need to rethink our understanding of Alzheimer’s progression, study suggests

To the non-scientist, the argument of what came first, the chicken or the egg may seem a bit esoteric. Yet ...
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Can synthetic biology help deliver an AI brain as smart as the real thing?

To create artificial general intelligence, we need to study the brain ...
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Neuroscience had a ‘transformative’ decade, giving us brain-computer interfaces, new research tools

I rarely use the words transformative or breakthrough for neuroscience findings. The brain is complex, noisy, chaotic, and often unpredictable ...
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Protein tangles may help predict where and how Alzheimer’s will strike the brain

Tangles of a protein found inside the brain cells of people with Alzheimer’s disease can be used to predict future ...
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Infographic: How exercise gives your brain a boost

Why does exercise affect the brain at all? Physical activity improves the function of many organ systems in the body, ...
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Deconstructing the idea that consciousness is a ‘spooky’ illusion

These days it is highly fashionable to label consciousness an ‘illusion’. This in turn fosters the impression, especially among the ...
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Pea-sized mini brains just developed brain waves for the first time

Mini-brains are just the size of a pea but capable of reproducing key brain functions. They are currently a hot research topic because scientists think they ...
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Children showing signs of autism should be treated before diagnosis is confirmed, under new guidelines

Pediatricians should start treating children who show signs of autism even before tests confirm a diagnosis, according to the newest ...
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Video: Neuroscientist Sergiu Pasca on his pioneering efforts to grow brain organoids from stem cells

When [Stanford University brain researcher Sergiu] Pasca started his own lab at the university in 2014, he continued working on ...
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