The GLP is committed to full transparency. Download and review our Annual Report.

d x

Gene control, delivered directly to the brain , could help cure diseases

A biotech company called Alnylam announced today that a small clinical trial for a genetic therapy based on RNA interference, ...

Certain human diseases may have evolutionary epigenetic origins

Ninety-six percent of a chimpanzee's genome is the same as a human's. It's the other 4 percent, and the vast ...

DNA deletions promote cancer, collateral damage makes it vulnerable

Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that ...
e

Stem cell trial for Autism launches in U.S.

Families with autistic children must navigate a condition where questions outnumber the answers, and therapies remain sparse and largely ineffective ...

What your neural stem cells aren’t telling you

In 2000, a team of neuroscientists put an unusual idea to the test. Stress and depression, they knew, made neurons ...
brainsavant

Newton’s Law: If an apple hits you on the head it can rewire your genetic circuitry, creating a savant

Getting smacked in the head is no picnic, as most football players, hockey players, and boxers would attest. Debilitating side ...

Stem cell research begins for spinal cord injury repair

The state's stem-cell institute has awarded $20 million to UC Irvine researchers, along with a private company, to prepare the ...

How do brain stem cells know when to act?

Working with mice, Johns Hopkins researchers say they have figured out how stem cells found in a part of the ...

Human stem cells found to restore memory

A California biotech company announced that its human stem cells restored memory in rodents bred to have an Alzheimer's-like condition—the ...

Genetics test reveals your cat’s ancestry

Ever wondered whether your feline hails from eastern Asia or the eastern Mediterranean? No need to rack your brain anymore ...

Personalized medicine closer to reality: Using stem cells to study variants of Parkinson’s disease

A nationwide consortium of scientists at 20 institutions, led by a principal faculty member at the Harvard Stem Cell Institute ...

New evidence for stem cells that spur cancer’s growth

For a decade, it’s been one of the most hotly debated questions in cancer: do tumors return despite powerful treatments ...
eb

Parkinson’s, Huntington’s disease research makes advances with stem cells

Two groups of Parkinson's and Huntington's researchers working in 13 labs nationwide have used advanced stem-cell technology to make human ...
breast cancer genes

Vast gene study raises hope for colon cancer drugs

More than 200 researchers investigating colon cancer tumors have found genetic vulnerabilities that could lead to powerful new treatments. The ...

Researchers turn skin cells into brain cells, a promising path to better Parkinson’s treatment

Using adult stem cells, Johns Hopkins researchers and a consortium of colleagues nationwide say they have generated the type of ...

Pediatric tumors traced to stem cells in developing brain

Stem cells that come from a specific part of the developing brain help fuel the growth of brain tumors caused ...

Transgenic technique to ‘eliminate’ a specific neural circuit of the brain in primates

In the brains of humans and non-human primates, over 100 billion nerve cells build up complicated neural circuits and produce ...

Common diabetes drug promotes development of brain stem cells

Researchers at The Hospital for Sick Children (SickKids) have found that metformin, a drug commonly used to treat Type II ...

Stem cell transplantation into mouse cochlea may impact future hearing loss therapies

Researchers in Japan who evaluated the risks and efficacy of transplanting two varieties of stem cells into mouse cochlea have ...

Gene therapy curbs nicotine addiction in mice

Forget patches: gene therapy could suppress cigarette cravings by preventing the brain from receiving nicotine. The treatment is effective in ...

Transgenic technique ‘eliminates’ a specific neural circuit in brain of primates

In the brains of humans and non-human primates, over 100 billion nerve cells build up complicated neural circuits and produce ...

Stress blocks gene that guards brain against depression

Chronic stress appears to block a gene that guards against brain atrophy associated with depression, according to a study in ...

Blood-brain barrier building blocks forged from human stem cells

The blood-brain barrier may be poised to give up some of its secrets as researchers at the University of Wisconsin-Madison ...

A huge step for gene therapy

A new gene therapy from researchers at National Taiwan University Hospital gives hope to children born with an extremely rare ...

Variations in sex steroid gene expression can predict aggressive behaviors

An Indiana University biologist has shown that natural variation in measures of the brain's ability to process steroid hormones predicts ...
f

Is genetic testing for dementia appropriate?

Would you want to know if you had a genetic risk factor forAlzheimer's or dementia? And, if you did know, ...
d e pt o

Do liars really have different brains?

As biology has advanced, it’s become increasingly clear that the environment and yes, even choice, have a remarkable impact on ...
brain alz

How do you live knowing you might have an alzheimer’s gene?

Though as much as 99 percent of all Alzheimer’s cases are not a result of a known genetic mutation, researchers ...