Upchuck factor: Alcoholism targeted with novel gene therapy

Upchuck factor: Alcoholism targeted with novel gene therapy

Researchers are exploring the use of a naturally occurring mutation that causes people to get sick after drinking alcohol. The ...
David Gorski: Rigvir 'virotherapy' another unproven alternative medicine cancer therapy

David Gorski: Rigvir ‘virotherapy’ another unproven alternative medicine cancer therapy

[Editor's note: Dr. David Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute.] [Cancer ...
Podcast: Exploring the consequences of gene editing's links to 'eugenics'

Podcast: Exploring the consequences of gene editing’s links to ‘eugenics’

[Editor's note: Paul Knoepfler, a UC-Davis biology professor and researcher, is interviewed by Guy Raz for NPR's Ted Radio Hour.] ...
First-ever gene-altering leukemia treatment approved by the FDA, uses patient cells to fight cancer

First-ever gene-altering leukemia treatment approved by the FDA, uses patient cells to fight cancer

The Food and Drug Administration on Wednesday approved the first-ever treatment that genetically alters a patient’s own cells to fight cancer, a milestone ...
Muscular dystrophy 'death sentence' targeted by gene therapy trials

Muscular dystrophy ‘death sentence’ targeted by gene therapy trials

[T]hree U.S. teams say they are ready to try to treat Duchenne [Muscular Dystrophy] with gene therapy. The first study ...
'Genome cloaking' could protect genetic privacy in medical tests

‘Genome cloaking’ could protect genetic privacy in medical tests

It is now possible to scour complete human genomes for the presence of disease-associated genes without revealing any genetic information ...
RNA editing could help slow progression of symptoms of ALS and Huntington's

RNA editing could help slow progression of symptoms of ALS and Huntington’s

The most common gene editing technique, CRISPR-Cas9, only modifies DNA. That's helpful in most cases, but it means that you can't ...
Three-person IVF as an infertility solution has a long way to go

Three-person IVF as an infertility solution has a long way to go

The procedure is typically targeted at parents who want to avoid passing a potentially fatal mitochondrial disease to their child ...
Could vitamin B3 supplements prevent birth defects?

Could vitamin B3 supplements prevent birth defects?

An extra dose of vitamin B3 might help prevent certain kinds of complex birth defects, according to a new study ...
Could gene editing have saved Charlie Gard?

Could gene editing have saved Charlie Gard?

The British infant died of a mitochondrial disease as news broke that US scientists had successfully edited a human embryo ...
Anti-aging hormone boosts cognitive abilities in mice – could humans be next?

Anti-aging hormone boosts cognitive abilities in mice – could humans be next?

[Klotho is] a naturally occurring hormone in the body. More than two decades ago, Japanese researchers discovered that this hormone ...
Why use gene editing on human embryos when other options are available?

Why use gene editing on human embryos when other options are available?

Researchers in the U.S. and South Korea have shown that gene editing can correct a genetic disorder in an embryo. Using CRISPR-Cas9, ...
CRISPR revolution: How scientists are turning gene-editing hype into food and medical breakthroughs

CRISPR revolution: How scientists are turning gene-editing hype into food and medical breakthroughs

The powerful gene-editing tool is becoming ubiquitous, appearing in the media with ever increasing frequency. But it's more than just ...
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We each have 3 billion base pairs in our genome. Artificial intelligence can help us sort it out.

Genes carry the information that make you you. So it's fitting that, when sequenced and stored in a computer, your ...
Are obesity, diabetes and other diseases treatable using gene-therapy skin grafts?

Are obesity, diabetes and other diseases treatable using gene-therapy skin grafts?

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how ...
Pioneering gene therapy restores vision to people with rare retinal blindness

Pioneering gene therapy restores vision to people with rare retinal blindness

Spark Therapeutics is moving forward with its treatment for a type of inherited retinal dystrophy. In the wake of the ...
Muscular dystrophy in dogs reversed with gene therapy--are children next?

Muscular dystrophy in dogs reversed with gene therapy–are children next?

Duchenne muscular dystrophy (DMD) is the most common and, sadly, the most severe form of the debilitating genetic disorder. Now ...
Beneficial 'natural' gene mutation could be effective in treating sickle cell

Beneficial ‘natural’ gene mutation could be effective in treating sickle cell

Sickle cell disease (SCD) patients have a genetic defect that leads them to produce hemoglobin S, or sickle hemoglobin, instead of ...
Gene therapy leukemia treatments approval expected by end of 2017

Gene therapy leukemia treatments approval expected by end of 2017

The approval of gene therapy for leukemia, expected in the next few months, will open the door to a radically ...
Do your kids have 'soccer genes'? The pseudoscience of many genetic tests

Do your kids have ‘soccer genes’? The pseudoscience of many genetic tests

[A] growing number of scientists [are] pushing back against wild claims in the consumer genetics market, which is flush with tests promising ...
Unwanted genes: Why can't we just edit them out of our lives?

Unwanted genes: Why can’t we just edit them out of our lives?

Gene therapy 2.0 using CRISPR to knock out harmful genes sounds is a great idea--if and when it works. But ...
First US gene therapy nears: CAR-T leukemia treatment gets nod from FDA panel

First US gene therapy nears: CAR-T leukemia treatment gets nod from FDA panel

Novartis AG's pioneering new cancer drug won enthusiastic support from a federal advisory panel on [July 12], paving the way for ...
'Molecular scalpel': Gene-editing technique promises greater precision

‘Molecular scalpel’: Gene-editing technique promises greater precision

A scientific team from in the Novo Nordisk Foundation Center for Protein Research (NNF-CPR), at the University of Copenhagen, has ...
NY Times' Carl Zimmer: CRISPR gene editing vital but offers ethical challenges

NY Times’ Carl Zimmer: CRISPR gene editing vital but offers ethical challenges

[Editor's Note: Carl Zimmer is a columnist at the New York Times, where his column "Matter" appears each week. He ...
Ectogenesis: Artificial placenta could aid premature babies, rekindle abortion debate

Ectogenesis: Artificial placenta could aid premature babies, rekindle abortion debate

Survival rates are likely to be improved for infants born prematurely, and those requiring invasive treatments -- including surgery, cell ...
CRISPR's high costs may limit development of gene therapy drugs

CRISPR’s high costs may limit development of gene therapy drugs

The ruckus over the CRISPR gene-editing system hides a dark reality: its high cost may make it unaffordable and questions ...
Bladder control: Is there a genetic treatment for urinary incontinence?

Bladder control: Is there a genetic treatment for urinary incontinence?

Treatment options for urinary incontinence may be revealed through a genome-wide association study searching for genes that may contribute to ...
HIV fix: Can gene editing work alongside the virus to provide a cure?

HIV fix: Can gene editing work alongside the virus to provide a cure?

HIV is no longer a death sentence in much of the developed world. But effective treatment in developing nations needs ...