Unwanted genes: Why can't we just edit them out of our lives?

Unwanted genes: Why can’t we just edit them out of our lives?

Gene therapy 2.0 using CRISPR to knock out harmful genes sounds is a great idea--if and when it works. But ...
First US gene therapy nears: CAR-T leukemia treatment gets nod from FDA panel

First US gene therapy nears: CAR-T leukemia treatment gets nod from FDA panel

Novartis AG's pioneering new cancer drug won enthusiastic support from a federal advisory panel on [July 12], paving the way for ...
'Molecular scalpel': Gene-editing technique promises greater precision

‘Molecular scalpel’: Gene-editing technique promises greater precision

A scientific team from in the Novo Nordisk Foundation Center for Protein Research (NNF-CPR), at the University of Copenhagen, has ...
NY Times' Carl Zimmer: CRISPR gene editing vital but offers ethical challenges

NY Times’ Carl Zimmer: CRISPR gene editing vital but offers ethical challenges

[Editor's Note: Carl Zimmer is a columnist at the New York Times, where his column "Matter" appears each week. He ...
Ectogenesis: Artificial placenta could aid premature babies, rekindle abortion debate

Ectogenesis: Artificial placenta could aid premature babies, rekindle abortion debate

Survival rates are likely to be improved for infants born prematurely, and those requiring invasive treatments -- including surgery, cell ...
CRISPR's high costs may limit development of gene therapy drugs

CRISPR’s high costs may limit development of gene therapy drugs

The ruckus over the CRISPR gene-editing system hides a dark reality: its high cost may make it unaffordable and questions ...
Bladder control: Is there a genetic treatment for urinary incontinence?

Bladder control: Is there a genetic treatment for urinary incontinence?

Treatment options for urinary incontinence may be revealed through a genome-wide association study searching for genes that may contribute to ...
HIV fix: Can gene editing work alongside the virus to provide a cure?

HIV fix: Can gene editing work alongside the virus to provide a cure?

HIV is no longer a death sentence in much of the developed world. But effective treatment in developing nations needs ...
Blood disease that plagued Europe's royal families might be treatable using gene editing

Blood disease that plagued Europe’s royal families might be treatable using gene editing

Researchers are hoping to use gene editing to create more effective and less expensive treatment options--compared to gene therapy--for people ...
Reversing Huntington's? Brain shown to heal itself after disease source edited out -- in mice

Reversing Huntington’s? Brain shown to heal itself after disease source edited out — in mice

The potential of genome-editing techniques, such as CRISPR/Cas9, to alleviate disease burden has ignited the imagination for thousands of researchers ...
Downside to editing out 'bad genes': We might need them later

Downside to editing out ‘bad genes’: We might need them later

[With CRISPR, couples] may soon be able to edit [genes linked to genetic disorders] right out of their own sperm, ...
Darwin Life: 'Three-parent babies' as a cure for age-related infertility

Darwin Life: ‘Three-parent babies’ as a cure for age-related infertility

John Zhang, a U.S. fertility doctor has started a company [called Darwin Life] with a provocative vision for older women: become ...
Which patients to choose for experimental CAR-T cancer therapy?

Which patients to choose for experimental CAR-T cancer therapy?

A transformative cancer therapy based on modified immune cells has lured doctors, companies, and patients alike, but many are hitting ...
CRISPR study reporting 'off-target mutations' draws skepticism from other researchers

CRISPR study reporting ‘off-target mutations’ draws skepticism from other researchers

A new study found an alarming number of “off-target mutations” in mice that had their genes edited with CRISPR. But ...
Read ELP’s Nicholas Staropoli Reddit Science ‘Ask Me Anything’ on Epigenetics: Hype and Health

Read ELP’s Nicholas Staropoli Reddit Science ‘Ask Me Anything’ on Epigenetics: Hype and Health

Editor’s Note: On Friday, June 2nd from 1pm–3pm EDT, ELP director Nicholas Staropoli hosted a Reddit-science Ask-Me-Anything (AMA) about the hype surrounding ...
Age-related macular degeneration may be treatable using viral injection gene therapy

Age-related macular degeneration may be treatable using viral injection gene therapy

[R]esearchers from Johns Hopkins Medicine were looking for ways to treat a particular type of age-related macular degeneration (AMD) known as a wet ...
Is gene therapy research for single-gene diseases at risk under Trumpcare?

Is gene therapy research for single-gene diseases at risk under Trumpcare?

[When] the House of Representatives passed the American Health Care Act of 2017,...DNA Science addressed the possibility of the AHCA forcing ...
Hemophilia cure? First attempt at in vivo human genome editing

Hemophilia cure? First attempt at in vivo human genome editing

Researchers have edited the human genome before, but always in cells outside the body. Now, biotech company Sangamo Therapeutics is ...
Pope Francis backs gene editing to treat human diseases, but cautions against 'throwaway culture'

Pope Francis backs gene editing to treat human diseases, but cautions against ‘throwaway culture’

Pope Francis praised scientists searching for treatments for genetic diseases but cautioned against the use of human embryos in their ...
Video: Micro-bubbles and stem cell gene therapy heal bone fractures in pigs

Video: Micro-bubbles and stem cell gene therapy heal bone fractures in pigs

It takes more than a cast and a little time to heal many broken bones....Now, researchers have combined ultrasound, stem ...
Gene therapy breakthrough for age-related macular degeneration

Gene therapy breakthrough for age-related macular degeneration

Wet age-related macular degeneration (AMD) occurs when blood vessels grow and leak fluid into the macula, the central portion of ...
CRISPR may open door to personalized treatment of cancer

CRISPR may open door to personalized treatment of cancer

One thing cells must do in order to become cancerous is to overthrow the normal checks on their growth. As ...
Eric Lander and Eric Schmidt: Science's Miracle Machine — government investment in basic research — in danger

Eric Lander and Eric Schmidt: Science’s Miracle Machine — government investment in basic research — in danger

[Editor's note: Eric S. Lander is president and founding director of the Broad Institute of MIT and Harvard University. Eric E ...
Bubble boy hope: Strimvelis gene therapy revises genetic make-up, offers rare immune deficiency cure

Bubble boy hope: Strimvelis gene therapy revises genetic make-up, offers rare immune deficiency cure

A child in Europe has become the second individual ever to receive a commercial gene therapy, according to GlaxoSmithKline. The ...
Are 3-parent babies products of eugenics or the desire to save lives?

Are 3-parent babies products of eugenics or the desire to save lives?

These days, using the tiniest surgical and biological scissors, we can snip away bad genes and insert good ones.thanks ...
Restoring sight: CRISPR could reprogram cells to treat retinitis pigmentosa

Restoring sight: CRISPR could reprogram cells to treat retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at ...
Does gene editing change who we are as 'humans'?

Does gene editing change who we are as ‘humans’?

DNA-based technology’s entry into the mainstream has been picking up lately.... But rapid advances mean it is becoming increasingly feasible ...
Knowledge without context: Downside of direct-to-consumer genetic tests

Knowledge without context: Downside of direct-to-consumer genetic tests

Direct-to-consumer genetic tests are growing in popularity. They can tell us a lot about our personal building blocks. But there ...