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Beneficial ‘natural’ gene mutation could be effective in treating sickle cell

Alice Melao | 
Sickle cell disease (SCD) patients have a genetic defect that leads them to produce hemoglobin S, or sickle hemoglobin, instead of ...
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Gene therapy leukemia treatments approval expected by end of 2017

Denise Grady | 
The approval of gene therapy for leukemia, expected in the next few months, will open the door to a radically ...
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Do your kids have ‘soccer genes’? The pseudoscience of many genetic tests

Kristen Brown | 
[A] growing number of scientists [are] pushing back against wild claims in the consumer genetics market, which is flush with tests promising ...
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First US gene therapy nears: CAR-T leukemia treatment gets nod from FDA panel

Toni Clarke | 
Novartis AG's pioneering new cancer drug won enthusiastic support from a federal advisory panel on [July 12], paving the way for ...
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‘Molecular scalpel’: Gene-editing technique promises greater precision

Ana Hernando | 
A scientific team from in the Novo Nordisk Foundation Center for Protein Research (NNF-CPR), at the University of Copenhagen, has ...
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NY Times’ Carl Zimmer: CRISPR gene editing vital but offers ethical challenges

Carl Zimmer | 
[Editor's Note: Carl Zimmer is a columnist at the New York Times, where his column "Matter" appears each week. He ...
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CRISPR’s high costs may limit development of gene therapy drugs

Jim Kozubek | 
The ruckus over the CRISPR gene-editing system hides a dark reality: its high cost may make it unaffordable and questions ...
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Bladder control: Is there a genetic treatment for urinary incontinence?

Ricki Lewis | 
Treatment options for urinary incontinence may be revealed through a genome-wide association study searching for genes that may contribute to ...
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HIV fix: Can gene editing work alongside the virus to provide a cure?

David Warmflash | 
HIV is no longer a death sentence in much of the developed world. But effective treatment in developing nations needs ...
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Reversing Huntington’s? Brain shown to heal itself after disease source edited out — in mice

The potential of genome-editing techniques, such as CRISPR/Cas9, to alleviate disease burden has ignited the imagination for thousands of researchers ...
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Downside to editing out ‘bad genes’: We might need them later

Moises Velasquez-Manoff | 
[With CRISPR, couples] may soon be able to edit [genes linked to genetic disorders] right out of their own sperm, ...
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Darwin Life: ‘Three-parent babies’ as a cure for age-related infertility

Emily Mullin | 
John Zhang, a U.S. fertility doctor has started a company [called Darwin Life] with a provocative vision for older women: become ...
Which patients to choose for experimental CAR-T cancer therapy?

Which patients to choose for experimental CAR-T cancer therapy?

Jennifer Couzin-Frankel | 
A transformative cancer therapy based on modified immune cells has lured doctors, companies, and patients alike, but many are hitting ...
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CRISPR study reporting ‘off-target mutations’ draws skepticism from other researchers

Ian Haydon | 
A new study found an alarming number of “off-target mutations” in mice that had their genes edited with CRISPR. But ...
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Read ELP’s Nicholas Staropoli Reddit Science ‘Ask Me Anything’ on Epigenetics: Hype and Health

Nicholas Staropoli | 
Editor’s Note: On Friday, June 2nd from 1pm–3pm EDT, ELP director Nicholas Staropoli hosted a Reddit-science Ask-Me-Anything (AMA) about the hype surrounding ...
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Age-related macular degeneration may be treatable using viral injection gene therapy

Dom Galeon | 
[R]esearchers from Johns Hopkins Medicine were looking for ways to treat a particular type of age-related macular degeneration (AMD) known as a wet ...
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Is gene therapy research for single-gene diseases at risk under Trumpcare?

Ricki Lewis | 
[When] the House of Representatives passed the American Health Care Act of 2017,...DNA Science addressed the possibility of the AHCA forcing ...
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Hemophilia cure? First attempt at in vivo human genome editing

Abby Olena | 
Researchers have edited the human genome before, but always in cells outside the body. Now, biotech company Sangamo Therapeutics is ...
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Pope Francis backs gene editing to treat human diseases, but cautions against ‘throwaway culture’

Felix Codilla III | 
Pope Francis praised scientists searching for treatments for genetic diseases but cautioned against the use of human embryos in their ...
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Video: Micro-bubbles and stem cell gene therapy heal bone fractures in pigs

Robert Service | 
It takes more than a cast and a little time to heal many broken bones....Now, researchers have combined ultrasound, stem ...
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Gene therapy breakthrough for age-related macular degeneration

Diana Kwon | 
Wet age-related macular degeneration (AMD) occurs when blood vessels grow and leak fluid into the macula, the central portion of ...
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CRISPR may open door to personalized treatment of cancer

Diana Gitig | 
One thing cells must do in order to become cancerous is to overthrow the normal checks on their growth. As ...
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Eric Lander and Eric Schmidt: Science’s Miracle Machine — government investment in basic research — in danger

Eric Lander, Eric Schmidt | 
[Editor's note: Eric S. Lander is president and founding director of the Broad Institute of MIT and Harvard University. Eric E ...
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Bubble boy hope: Strimvelis gene therapy revises genetic make-up, offers rare immune deficiency cure

Emily Mullin | 
A child in Europe has become the second individual ever to receive a commercial gene therapy, according to GlaxoSmithKline. The ...
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Are 3-parent babies products of eugenics or the desire to save lives?

Jill Neimark | 
The most astonishing gene therapy news this year has been the crafting of three-parent babies. The in-vitro fertilization practice, known ...
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Restoring sight: CRISPR could reprogram cells to treat retinitis pigmentosa

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at ...
Does gene editing change who we are as 'humans'?

Does gene editing change who we are as ‘humans’?

Edd Gent | 
DNA-based technology’s entry into the mainstream has been picking up lately.... But rapid advances mean it is becoming increasingly feasible ...
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