low tech

Transforming modern medicine doesn’t have to be high tech or expensive

Henry Miller | 
While intricate high-tech breakthroughs are incredible, it's important to realize the value of low-cost and low-tech ingenuity ...
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CAR-T cell therapy could drive a ‘revolution’ in cancer treatments

Emma Bryce | 
[T]he United States Food and Drug Administration (FDA) made the landmark decision to approve two ‘drugs’ that use CAR-T cell ...
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Esophageal cancer treated with risky modified T-cell therapy in China

Kyree Leary | 
Esophageal cancer is one of the most common forms of cancer in China. Like many other types, cancer of the esophagus ...
gene

Cutting gene therapy side effects by finding a better delivery system to the brain

Mark Derewicz | 
Researchers have found a structure on the small viruses that deliver gene therapy that makes them better at crossing from ...
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Stop AIDS? Gene therapies target ‘almost impossible to cure’ HIV

Jaleesa Baulkman | 
Experts say gene therapy could finally be used to treat HIV and AIDS - after a decade of trying to replicate the ...
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Video: Biohacker documents his own DIY gene therapy

David Grossman | 
DIY gene therapy is far from the mainstream, but the numbers of people who are attempting to genetically engineer their ...
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Gene-editing advances put us at the dawn of a revolution in medicine

Steven Cerier | 
So much of the public's attention is focused on the use of genetic engineering in the crops that our farmers ...
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Incurable arthritic knees? Gene therapy offers new hope

Ricki Lewis | 
Imagine a single injection into the knee vanquishing painful arthritis — forever. Gene therapies aimed at two molecular targets could ...
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Former Novartis chief Joseph Jimenez discusses breakthroughs in gene therapy, future of CRISPR in medicine

Joseph Jimenez, Karen Weintraub | 
Editor's Note: Novartis CEO Joseph Jimenez retired in January after eight years in the top job at one of the ...
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Gene therapy setback? Animal deaths in treating muscular dystrophy spark new concerns over high doses

Antonio Regalado | 
An influential scientist involved in gene therapy’s biggest setback, the death of a study volunteer 19 years ago, has issued a ...
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Search and destroy: CAR-T cell therapy could give patients HIV immunity

Enrique Rivero | 
A UCLA-led research team has created blood-forming stem cells that can carry a gene that allows the body to produce cells ...
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Human muscles from stem cells: Advance could aid research into muscular dystrophy, other diseases

Ricki Lewis | 
Muscle created with stem cells is not quite as strong as the researchers would like. But they think these new ...
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China poised to do gene therapy ‘better and cheaper’ than US

Shuli Ren | 
China wants to go big on biotech and already is marching into experimental gene therapy. … So far, CAR-T has ...
Clinical Research

‘Supercharged’ T-cells show promise against Hodgkin’s lymphoma

Michael Irving | 
Cancer has been winning the arms race against the immune system for too long, but scientists are developing plenty of ...
woman cancer patient

Rural-urban divide: Groundbreaking gene therapies could exacerbate inequality in cancer care

Emily Mullin | 
Two new cancer treatments have shown miraculous cures, but if you happen to live in Arkansas or Montana, or a ...
gene therapy

Report: Price for blindness gene therapy Luxturna is ‘four times too high’ at $850,000

Andrew Joseph | 
The $850,000 list price for a new medicine that treats a genetic form of childhood blindness is about four times too high ...
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Can gene therapy reduce terminal cancers to minor chronic diseases that are ‘no different than high blood pressure’?

Todd Balf | 
On Oct. 15 at 8 a.m., Andy Lindsay stood atop 21,247-foot Mera Peak in Nepal, a wildly improbable place for ...
gene therapy

CAR-T gene therapy treatments may fall short of corrective goals, requiring surgical gene editing

Thomas Reinke | 
For decades, researchers, some physicians, and a few patients have had visions of treatments that would go in and fix ...
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Could we fight HIV with new Car-T therapy?

Sharon Begley | 
The same kind of DNA tinkering that produced the first FDA-approved gene therapy for cancer has shown hints of suppressing and even ...
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Luxturna gene therapy approved for vision loss

Julianna LeMieux | 
The first two novel gene therapies for cancer treatment passed through FDA approval earlier this year, first B-cell acute lymphoblastic leukemia (ALL) followed quickly ...
gene therapy

Should patients—not the FDA— have final say on risky gene therapy treatments?

Dave Roos | 
Working with mice, researchers have used gene therapy to restore sight to the blind, reprogram the body’s own T cells ...
breakthrough

Looking back at 2017’s genetics breakthroughs

Kristen Brown | 
It was a big year for the building blocks of life. Here were the most significant breakthroughs in genetics research ...
gene editing

Should it matter if the public is wary of gene editing and human enhancement?

Grant Jacobs | 
A survey of people in the US and 10 European nations found opposition to some forms of gene editing for ...
GEN

FDA approves first gene therapy for a genetic disease—onetime cure for rare blindness

Linda Loyd | 
The first gene therapy to restore sight to individuals who suffer from a rare inherited genetic blindness was approved by ...
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Italian family’s inability to feel pain spurs research on relief for chronic sufferers

Ricki Lewis | 
The six members of the family barely notice broken bones or severe burns. Researchers have identified the mutation behind their ...
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Hemophilia A gene therapy trial results: ‘This is huge’

James Gallagher | 
British doctors say they have achieved "mind-blowing" results in an attempt to rid people of haemophilia A. Patients are born ...
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Cancer treatment without chemotherapy? CAR T-cells could become the new standard

Victoria Forster | 
Although rare, it is not unheard-of for new treatments to achieve substantial early successes in one or two patients only ...
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