Over the next decade, CRISPR and other forms of gene editing could help people with rare disorders — and millions more with heart disease, diabetes, and chronic pain

Over the next decade, CRISPR and other forms of gene editing could help people with rare disorders — and millions more with heart disease, diabetes, and chronic pain

In the next decade, Crispr-Cas9 and other new gene-editing techniques may protect the health [of] millions of people with a ...
Is embryo gene editing a technology we can afford — ethically and morally? Hank Greely address the future in ‘CRISPR People’

Is embryo gene editing a technology we can afford — ethically and morally? Hank Greely address the future in ‘CRISPR People’

The following is an excerpt from Hank Greely’s book CRISPR People. I see no inherent or unmanageable ethical barriers to ...
‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size

‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size

If I had to pick one country that might be the epitome of the ‘Wild West’ of reproductive and genetic ...
Video: Viewpoint — The upside is immense but ‘threats from CRISPR gene editing are too big to ignore’

Video: Viewpoint — The upside is immense but ‘threats from CRISPR gene editing are too big to ignore’

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary technology that gives scientists the ability to alter DNA. On ...
The age of genetically-enhanced children is approaching. Novelist Kazuo Ishiguro imagines a have-and-have not future, and it’s not pleasant

The age of genetically-enhanced children is approaching. Novelist Kazuo Ishiguro imagines a have-and-have not future, and it’s not pleasant

Biotech interventions to help sick children—like gene therapy—are approached with supreme caution. If a treatment has a reasonable chance of ...
400,000 people – that’s how many die from malaria each year. Here’s how gene editing and gene drives could prevent those deaths

400,000 people – that’s how many die from malaria each year. Here’s how gene editing and gene drives could prevent those deaths

The estimated number of malaria deaths stood at 409,000 in 2019. There is an urgent need to find new ways ...
CRISPR can alter an embryo's genes forever. What happens when there are ‘mistakes’?

CRISPR can alter an embryo’s genes forever. What happens when there are ‘mistakes’?

[He Jiankui] made the first genetically modified babies in the history of humankind. After 3.7 billion years of continuous, undisturbed ...
Podcast: Ezra Klein and Walter Isaacson discuss how CRISPR is poised to redirect the future course of evolution

Podcast: Ezra Klein and Walter Isaacson discuss how CRISPR is poised to redirect the future course of evolution

When future generations look back on this moment in history, will they remember the daily political fights — or will ...
How does CRISPR’s ‘on-off switch’ work? How will it revolutionize genetic research and the development of therapies?

How does CRISPR’s ‘on-off switch’ work? How will it revolutionize genetic research and the development of therapies?

[R]esearchers have published perhaps the greatest advance since 2013 – a way to use CRISPR as an on-off switch for ...
CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to ...
An ‘off button’ for pain? CRISPR could stop the opioid crisis by tackling chronic pain at the source

An ‘off button’ for pain? CRISPR could stop the opioid crisis by tackling chronic pain at the source

[In 2006, researchers found a family in Pakistan with] mutations in a gene called SCN9A. Two other families in northern ...
Here’s the skinny on the CRISPR patent saga between the Broad Institute and the CVC group

Here’s the skinny on the CRISPR patent saga between the Broad Institute and the CVC group

CRISPR was first reported by Jennifer Doudna and Emmanuelle Charpentier in 2012, as an outgrowth of their work on bacterial ...
CRISPR gene editing roils public discussion over ‘what it means to be disabled’

CRISPR gene editing roils public discussion over ‘what it means to be disabled’

The gene-editing technology CRISPR promises enormous potential as a therapeutic for curing illnesses, including potentially devising new vaccines.  But the ...
Quickly-advancing human embryo research raises prickly ethical questions

Quickly-advancing human embryo research raises prickly ethical questions

Nature published two peer-reviewed papers about generating in vitro, with slightly different methods, “blastoids” or “human blastocyst-like structures”... Notably, none ...
Who will win the battle over CRISPR-Cas 9 patent rights?

Who will win the battle over CRISPR-Cas 9 patent rights?

History is full of cases in which several researchers have found the same or similar inventions almost simultaneously. This is ...
‘What we have right now does not work’: Gene editing aims to relieve chronic pain

‘What we have right now does not work’: Gene editing aims to relieve chronic pain

In experiments on laboratory mice, researchers found that temporarily repressing a gene involved in sensing pain increases pain tolerance, lowers ...
Critics say gene drives could lead to species extinction. Scientists have developed a brake system

Critics say gene drives could lead to species extinction. Scientists have developed a brake system

By exerting control over the degree of spread, those who unleash gene drives may realize the benefits promised by gene ...
‘Scorching ethical debate’: Designer babies are already here. The future looks even more revolutionary — and contentious

‘Scorching ethical debate’: Designer babies are already here. The future looks even more revolutionary — and contentious

In one sense, genetically modifying a child with particular traits is already done on a fairly large scale. Couples with ...
Jennifer Doudna on how CRISPR is moving out of the lab to transform medicine and revolutionize disease treatments

Jennifer Doudna on how CRISPR is moving out of the lab to transform medicine and revolutionize disease treatments

In 2021, we will see increased use of CRISPR-Cas enzymes to underpin a new generation of cost-effective, individualised therapies. With ...
‘Gene editing is part of the solution’: With other sustainable farming tools, it will help us beat climate change

‘Gene editing is part of the solution’: With other sustainable farming tools, it will help us beat climate change

Despite changes in temperature, humidity and fertilizer application, [plants of the future] must be able to produce optimally. In addition, ...
The downside of ‘improving’ humanity: How CRISPR could edit out ‘abnormal genes’ — and human diversity

The downside of ‘improving’ humanity: How CRISPR could edit out ‘abnormal genes’ — and human diversity

CRISPR has many functions; one of these is that it can be used to treat disease. Yet the far-reaching, more ...
screen shot at am

Could there ever be a vaccine for breast cancer?

Triple-negative breast cancer, about 10% of all breast cancers, is one of the most aggressive and deadliest forms of this ...
Can CRISPR tame avian flu and prevent the next pandemic?

Can CRISPR tame avian flu and prevent the next pandemic?

Now that the COVID-19 vaccine rollout is picking up steam, it’s tempting to hope that the world can soon move ...
antibiotics

Using CRISPR to fight antibiotic-resistant ‘superbugs’

The superbugs are winning the antibiotics wars. CRISPR could turn the tide ...
Plant breeding efforts strained by climate change and booming food demand. Is CRISPR the answer?

Plant breeding efforts strained by climate change and booming food demand. Is CRISPR the answer?

Human population growth has increased the demand for food crops, animal feed, biofuel and biomaterials, all the while climate change ...
What’s in the biomedical pipeline for CRISPR gene editing?

What’s in the biomedical pipeline for CRISPR gene editing?

One great attraction of Crispr, says Niren Murthy, a bioengineer at Berkeley, is that it could be a one-shot affair ...
What CRISPR can do for the world

What CRISPR can do for the world

What might CRISPR do to the diversity of our species? If we are no longer subject to a natural lottery ...
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