Human Gene Editing
At-home biohacking using CRISPR to edit DNA? You can do it with a kit
Genetic engineering using CRISPR from the comfort of home might seem futuristic, but you can do it right now ...
Publicity stunt? Chinese embryo-tinkering scientist supports limitations on gene editing embryos — but refuses to discuss his 2018 CRISPR experiment
He Jiankui refused to answer researchers’ questions about his controversial 2018 experiments at weekend event ...
Million-dollar gene therapies offer salvation for many patients but pose financial challenges for government-funded health care systems
A wave of transformative but hugely expensive treatments is challenging the budgets of health systems in wealthy nations. Now countries ...
What guardrails should be set when using gene editing to improve our species? March global meeting of scientists will address
As the world’s top human genome editing researchers gather in London, the ethical issues posed by pioneering scientific advances will ...
Gene therapy delivered directly to the brain treats extremely rare disease in children
When Rylae-Ann Poulin was a year old, she didn’t crawl or babble like other kids her age. A rare genetic ...
‘Garage scientists’ can biohack their way to the newest health craze — and potentially make bioweapons. Should we be worried?
Anyone who can follow a recipe and has enough money to buy a pipette can modify their DNA at home ...
‘Perfect human’? Genetics researchers ponder ethical consequences of tinkering with human DNA
Researchers are investigating ways to use genome editing to tackle sickle cell anaemia, muscular dystrophy, cancer, diabetes and some forms ...
Zinc fingers: New AI-powered biotech innovation could offer unique advantages over CRISPR when building gene-editing disease therapies
A new study has developed what the researchers call the "world's first" simple, modifiable proteins. Called "zinc fingers," these special ...
CRISPR gene editing can treat heart disease and repair damaged tissue after a heart attack
Every year cardiovascular disease accounts for about 32% of all deaths worldwide. Researchers from the University of Texas Southwestern Medical ...
Viewpoint: Malaria kills half a million people each year. Here’s how CRISPR gene edited mosquitoes could end this scourge
Genetically modified mosquitoes … could CRISPR gene editing end malaria? This article tells the story of Target Malaria, a project ...
Cancer vaccine progress: CRISPR-developed shot stops brain tumors in mice
Cancer of the brain and nervous system accounted for over 250,000 deaths worldwide in 2020 ...
Could a vaccine permanently protect us from heart disease? CRISPR gene editing poised to provide healthcare solutions for most everyone
Last year, Verve Therapeutics started the first human trial of a CRISPR treatment that could benefit most people—a signal that ...
Viewpoint — ‘Bigotry dressed up as biology’: Geneticist Adam Rutherford’s 8 surprising facts about eugenics
Adam Rutherford is a geneticist and the author of Control: The Dark History and Troubling Present of Eugenics where he ...
CRISPR gene editing scientist who illegally manipulated embryos wants to cure genetic diseases. Should the scientific community trust him?
He Jiankui discusses his plans for finding cures for devastating genetic diseases. Should the scientific community trust him? ...
CRISPR gene editing is in clinical trials to treat sickle cell disease, cancer, HIV/AIDS and some rare inherited diseases. Here’s what we can expect going forward
When Jennifer Doudna and Emmanuelle Charpentier revealed that the bacterial Crispr–Cas9 antiviral defence system could be reprogrammed to edit genomic ...
Have gene therapy and gene editing techology progressed enough to deliver life-saving results?
Gene therapy has had a long and bumpy history. Although researchers have made some notable and recent progress, past failures—including some ...
Using cancer cells to kill tumors? Cell therapy engineered to eliminate and prevent brain cancer in advanced mouse model
Researchers took advantage of living tumor cells' unique ability to travel long distances across the brain to return to the ...
‘Zero detectable cancer cells’: Experimental CRISPR tool appears to cure 13-year-old’s ‘incurable’ leukemia
World-first: Experimental CRISPR technology removes detectable cancer cells in 13-year-old. Alyssa received genetically modified cells that could chase and kill ...
Single shot genetic cures are coming. Will insurance companies pay for these multi-million dollar therapies?
Some of Steven Pipe’s hemophilia patients consider themselves cured. In a trial Pipe led from 2018 to 2021, they received ...
CRISPR and gene drives: Revolutionary tool to address pest control or potential weapon of mass destruction?
You’ve probably heard of the gene-editing tool CRISPR, often referred to as “word processing for DNA.” Much of the attention ...
CRISPR gene editing could help cure as many as 7,000 diseases. What’s holding things up?
The parents of a 2-year-old girl write that their daughter “could die within the next year” because a genetic mutation ...
He Jiankui — CRISPR babies mastermind — is out of prison. What’s next for his career?
He Jiankui, the Chinese biophysicist who created the first gene-edited children, had been quiet since completing a three-year prison sentence in April, ...
Single-dose CRISPR gene editing technology helps train patients’ immune systems to fight cancer
For the first time, researchers have used CRISPR technology to substitute genes in patients’ immune cells to treat cancer. Participants ...
Poor cholesterol? A gene-edited solution could lower ‘bad’ LDL and reduce heart disease risk
While a poor diet, stress, lack of exercise, and other lifestyle factors can lead to cholesterol problems, genetic factors also ...
Children born during the great depression aged rapidly later in life. Here’s how trauma can affect you before you’re even born
The worst recession in US history shaped how well people would age — before they were even born. Researchers have ...
Viewpoint: Gene editing is revolutionizing medicine — but it opens a Pandora’s box of ethical questions
Genetic engineering or genetic modification has long been a headline grabber, often framed in a negative light. However we need ...
Viewpoint: ‘What’s the biological equivalent of an atomic bomb’? Here’s how the gene editing revolution could go astray
We now sequence the genes of people, animals, plants and tumors routinely. We’re starting to edit DNA, not only in ...