Experimental treatment to use CRISPR to dramatically lower cholesterol under scrutiny after two patients suffer heart attacks and one dies

Experimental treatment using CRISPR to dramatically lower cholesterol under scrutiny after two patients suffer heart attacks and one dies

Sharon Adarlo&nbsp|&nbsp
Researchers have been able to reduce bad cholesterol in human subjects after injecting them with an experimental gene editing treatment ...
CRISPR gene editing tackles yet another health scourge: High cholesterol

CRISPR gene editing tackles yet another health scourge: High cholesterol

Rob Stein&nbsp|&nbsp
Study shows that gene-editing technology can be used to successfully treat a genetic disorder that increases the risk of heart ...
Catholic ethics raises doubts about our 'superhuman' genetic future

Playing God: Catholic ethical experts caution against ‘superhuman’ genetic future

Quinton Amundson&nbsp|&nbsp
CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats: Ethicists fixate on this innovation creating “superhumans.” ...
First CRISPR medicine: UK approves Casgevy for treating sickle cell disease and beta thalassemia

First CRISPR drug: UK approves Casgevy to prevent pain from sickle cell disease and beta thalassemia

Emily Mullin&nbsp|&nbsp
The gene-editing therapy Casgevy uses Crispr to prevent debilitating pain in patients with sickle cell disease ...
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100,000 Americans, mostly Black, are victims of sickle cell anemia. CRISPR is on the cusp of treating it

Henry Miller&nbsp|&nbsp
Exa-cel, a new gene therapy treatment using CRISPR technology, shows promise in treating SCD by editing the patient's stem cells ...
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First clinical trial of CRISPR cure for HIV is encouraging — but comes with scant details

Kristin Houser&nbsp|&nbsp
California-based biotech company Excision BioTherapeutics has shared data from the first human clinical trial of a CRISPR cure for HIV ...
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Gene therapy treatment restores hearing to five children in China. Will the results last?

Antonio Regalado, Zeyi Yangar&nbsp|&nbsp
After deafness treatment, Yiyi can hear her mother and dance to the music. But why is it so noisy at ...
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Viewpoint: Breaking taboos or pioneering breakthroughs? Weighing ethics of gene editing of human embryos

Isabelle Bartram&nbsp|&nbsp
The German Ethics Council has now also ruled that inheritable genome editing is fundamentally morally permissible ...
Breakthrough CRISPR treatment for sickle cell anemia up for FDA approval

Breakthrough CRISPR treatment for sickle cell anemia up for FDA approval

Heidi Ledford&nbsp|&nbsp
Advisers to the US regulatory agency will examine the safety profile of a CRISPR-based treatment for sickle-cell disease ...
Science vs. equity: The debate over the future of gene editing intensifies

Science vs. equity: Debate over future of gene editing intensifies

Devika Rao&nbsp|&nbsp
Turning to genetic modification could be a solution for a number of genetic diseases including sickle cell anemia, muscular dystrophy ...
A CRISPR gene-editing tool has been added to three people with HIV, the virus that causes AIDs. Is it working?

A CRISPR gene-editing tool has been added to three people with HIV, the virus that causes AIDS. Is it working?

Antonio Regalado&nbsp|&nbsp
CRISPR is being used in an experimental effort to eliminate the virus that causes AIDS. The result is unknown ...
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Antibiotic resistance is rising and seems unstoppable. CRISPR-designed molecules might offer an answer

Nicoletta Lanese&nbsp|&nbsp
Antibiotics drive bacteria toward drug resistance, so scientists are looking to viruses, CRISPR, and designer molecules for better treatments ...
The speed of change spurred by gene editing is outpacing ethical constraints. This could be the consequences

Speed of breakthroughs spurred by gene editing is outpacing ethical constraints. These could be the consequences

Dana Goodyear&nbsp|&nbsp
The Chinese researcher He Jiankui was jailed for creating customized babies. Some observers argue that the real problem wasn’t him—it ...
Biotechnology timeline: Humans have manipulated genes since the 'dawn of civilization'

Biotechnology timeline: Humans have manipulated genes since the ‘dawn of civilization’

Brian Colwell&nbsp|&nbsp
The history of biotechnology shows how humans have been manipulating nature for our benefit for a long time—and how modern ...
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Genes and sexuality: Could epigenetics help us understand the mystery of sexual orientation?

Benjamin Oldroyd&nbsp|&nbsp
Reports of genes that “cause” human homosexuality (and many other human behaviours) have failed to stand up to scrutiny – ...
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Treating mental health disorders: Is CRISPR a long-hoped-for silver bullet?

Sam Moxon&nbsp|&nbsp
“I was born with the murder gene.” That’s the chilling statement in a true-life story featured in Esquire years ago ...
What makes an embryo an embryo? Lab-grown synthetic fertilized eggs scramble conventional science

What makes an embryo an embryo? Synthetic fertilized eggs scramble conventional science

Megan Molteni&nbsp|&nbsp
The mainstreaming of IVF, or in vitro fertilization, has familiarized new generations of people with what the earliest stages of ...
A gene therapy treatment for rare SMA syndrome costs $2 million dollars. What happens if it doesn’t cure the disease?

A gene therapy treatment for rare SMA syndrome costs $2 million dollars. What happens if it doesn’t cure the disease?

Deena Beasley&nbsp|&nbsp
Spinal muscular atrophy, a rare inherited disorder which is the leading genetic cause of death in infancy globally ...
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Lab-grown babies: Synthetic eggs and sperm get closer to reality

Willow Shah-Neville&nbsp|&nbsp
The technique used to potentially develop lab-grown babies could hold the power to provide a novel treatment option for human ...
‘Humanity enters an age of controlling destiny’—Chinese scientist He Jiankui’s roadmap for transforming the future of human evolution

Humanity enters an age of controlling destiny: Chinese scientist He Jiankui’s roadmap for transforming future of human evolution

Dana Goodyear&nbsp|&nbsp
The Chinese researcher He Jiankui was jailed for creating customized babies. Some observers argue that the real problem wasn’t him—it ...
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We could use CRISPR to cure mental illness. Should we?

Grace Spencer&nbsp|&nbsp
Would you want to be cured of a disorder that most people consider debilitating if given the opportunity? Cancer? Sure ...
mRNA technology revolution: Battling sickle cell, aging and other tough-to-tackle diseases will soon be easier and cheaper

mRNA technology revolution: Battling sickle cell, aging and other tough-to-tackle diseases will soon be easier and cheaper

Michael Le Page&nbsp|&nbsp
A technique for delivering mRNAs to blood stem cells should enable better and cheaper treatments for conditions from sickle cell ...
Training our taste buds: How genes and diet shape our food preferences

Training our taste buds: How genes and diet shape our food preferences

Monica Dus&nbsp|&nbsp
Have you ever wondered why only hummingbirds sip nectar from feeders? Unlike sparrows, finches and most other birds, hummingbirds can taste ...
China’s He Jiankui’s new gene editing experiment: CRISPR baby scientist aims to prevent Alzheimer’s with similar — but safer — experiment

He Jiankui’s new gene editing experiment: China’s CRISPR baby scientist aims to prevent Alzheimer’s with similar — but safer — experiment

Dong Lyu, John Liu&nbsp|&nbsp
The Chinese scientist who was at the center of global condemnation for altering babies’ genes wants to use a similar ...
Biotechnology giant: Is China now the world leader in human and agricultural genetic engineering?

Biotechnology giant: Does China now lead the world in human and agricultural genetic engineering?

Willow Shah-Neville&nbsp|&nbsp
For many people, when they hear China and genetic engineering in the same sentence, it is often synonymous with scandal, ...
‘Making a new person from skin or blood cells’ but no egg and sperm?’ Scientists debate ethics of ‘synthetic human reproduction

Making a new person from skin or blood cells — but no egg and sperm?’ Scientists debate ethics of ‘synthetic human reproduction’

Karen Weintraub&nbsp|&nbsp
Called in vitro gametogenesis, or IVG, it promises to someday provide a cure for many types of infertility ...
Editing out diseases in the womb is a Holy Grail of the near future. But protecting embryos from unwanted damage during the process is proving a challenging hurdle

Editing out diseases in the womb is a holy grail on the horizon — but protecting embryos from unwanted damage is proving a challenging hurdle

Megan Craig&nbsp|&nbsp
Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA ...
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