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Geopolitics of gene editing

For a handful of countries, gene editing is key to their future power ...
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Does a future with genetic enhancements undermine ‘the idea that we are all equal’?

Sex is how humans propagate. But developments in genetic engineering might change this one day. “We are, in the future, ...
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Searching for a CRISPR antidote in case gene editing is used as a weapon

[W]hat’s to stop a madman, terrorist, or state from employing CRISPR to cause harm?... In her book A Crack in Creation, ...
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With a simple tweak, CRISPR’s genetic scissors get an accuracy boost

Without ensuring high levels of accuracy, any proposed CRISPR gene therapy becomes a genetic crapshoot. Now, a team from Duke ...
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Japanese researchers gain approval for ‘basic research’ on gene-edited human embryos

A government research panel specializing in life ethics approved the modification of genes from fertilized human eggs for basic research ...
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‘Countries have been invaded for far less’: Why the genetic arms race could start a war

Imagine you are the leader of a society that has chosen to opt out of the genetic arms race by ...
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Could we be designing babies from a menu of genetic options in 2045?

The year is 2045. The genomes of four billion humans have been sequenced, creating a huge pool of genetic information ...
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Off-target RNA mutations: Why this ‘more precise genome-editing’ technique needs improvement

Base editors designed to convert one DNA nucleotide to another may also perform large numbers of unwanted edits to RNA, ...
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Why we lose when Hollywood distorts CRISPR gene editing in the name of entertainment

Adding misinformation to a climate of fear and distrust plants more seeds of suspicion in the public mind ...
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CRISPR ‘moving out of the lab’ in first US cancer trial

We've finally reached the moment when CRISPR is moving out of the lab and into the clinic around the world ...
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Families plagued by inherited diseases push back against ban on gene-edited embryos

In 2012, scientists showed that CRISPR, an ancient bacterial immune system, can edit DNA. ... Barely three years after, leaders in ...
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Viewpoint: He Jiankui’s CRISPR babies experiment was ‘even worse than I first thought’

When He Jiankui announced the birth of twin girls whose DNA he had modified when they were embryos using the CRISPR ...
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Stanford investigation clears faculty members that knew about CRISPR baby scandal

A Stanford investigation has cleared three prominent faculty members of helping with a controversial gene-editing experiment led by disgraced Chinese ...
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3 promising CRISPR therapies, including one targeting Duchenne Muscular Dystrophy

With dozens of efforts in the making, from premature aging to obesity and developmental brain disorders, here are the frontrunners ...
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Transparency and trust: Is there room for ‘the people’ in the human gene editing debate?

How does excluding the people service the WHO's stated goals of transparency and trust? ...
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Can light-activated CRISPR lead to new treatments for cancer, diabetes?

Engineers are making their mark on biotech’s hottest commodity. Chinese scientists [April 3] reported that they can control the gene editing tool CRISPR-Cas9 with ...
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Viewpoint: Gene-edited kids are no riskier than the non-edited variety

"The introduction of genetic modifications into future generations could have permanent and possibly harmful effects on the species," a group ...
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CRISPR’s challenge: It’s still easier to subtract genes than it is to add them

Almost always, building something is harder than tearing it down. Similarly, knocking in genes poses a greater challenge than knocking ...
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Why Nobel laureate David Baltimore doesn’t support moratorium on CRISPR babies

Some scientists have recently proposed a temporary moratorium on editing that would result in babies that carry heritable changes. … Science ...
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Video: CRISPR pioneer Jennifer Doudna explains Cas-9 gene editing

Prof Jennifer Doudna, one the pioneers of Crispr-Cas9 gene editing, explains how this revolutionary discovery enables precise changes to our ...
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Viewpoint: No, we don’t need a moratorium on germline gene editing

Should researchers put the brakes on genetically engineering babies? Leading scientists and ethicists recently called for a moratorium on clinical applications of germline ...
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Can the RNA editing race challenge the potential of CRISPR’s DNA editing?

RNA, a short-lived cousin to its better-known partner DNA, is the blueprint for protein production in cells. [Biotech entrepreneur Joshua] ...
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Genetically engineered humans: How do we decide when it’s ethical to create them?

Bioethicist Matthew Liao is open to genetic engineering in theory, but he says he was rather horrified to learn that ...
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Is society ready for the changes CRISPR can bring?

Crispr works in almost every animal that scientists have tried, from silkworms to monkeys, and in just about every cell ...
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Gene-editing rock stars: Geneticists set record with 13,200 CRISPR edits of single cell, opening door to ‘radical redesign’ of species

Since its invention, CRISPR has let scientists introduce DNA changes at specific locations in a genome. Often these precise changes ...
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We need a ‘global registry’ of all human gene-editing research, World Health Organization panel says

An influential committee of the World Health Organization said on [March 19] that it would be “irresponsible” to try to ...
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The promise of genetic engineering in medicine could be threatened by ‘bad press’

Because the disorder is caused by a single mutation in a single gene, sickle cell disease has long been seen ...
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When targeting diseases, how worried should we be about CRISPR’s potential for gene-editing errors?

Of all the big, world-remaking bets on the genome-editing tool known as Crispr, perhaps none is more tantalizing than its ...