Human Gene Editing/CRISPR
Using gene editing to merge an organism’s chromosomes into ‘one giant molecule’
Complex organisms have complex genomes. While bacteria and archaea keep all of their genes on a single loop of DNA, ...
What is CRISPR? And why should you care?
If you haven’t heard of CRISPR yet, the short explanation goes like this: In the past six years, scientists have ...
Using CRISPR to map human gene functions
UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in ...
How bacterial CRISPR defense systems are defeated by suicidal virus attacks
The natural world abounds with examples of predators that cooperate to take down their prey. And such teamwork also exists ...
Viewpoint: We’re ‘nowhere close’ to being ready to edit human genomes
Genome meddling to cure diseases is often worth the risk, but nothing else is just yet ...
‘Morally permissible’: Genetically altered babies get nod from UK ethics panel
The creation of babies whose DNA has been altered to give them what parents perceive to be the best chances ...
Why does CRISPR randomly fail 15% of the time?
The CRISPR gene editing process is known to fail about 15 percent of the time. These random failures have until ...
‘No reason to panic’: Experts react to study suggesting CRISPR isn’t as precise as we thought
A new study, published in Nature Biotechnology, investigates the use of CRISPR/Cas9 to make simple cuts in DNA in mouse ...
Gene drives could speed up inheritance of certain beneficial traits in mammals, study finds
Researchers have used CRISPR, the genome editing tool, to speed the inheritance of specific genes in mammals for the first ...
Viewpoint: CRISPR gene editing might quell ‘frankenfood’ fears and win consumer support for biotech
The debate surrounding genetically engineered (“GE” or “GMO”) plants and animals has historically been, and still is, extremely divisive. Anti-GMO ...
‘Wake-up call’? CRISPR gene editing may cause ‘genetic havoc’, study suggests
From the earliest days of the CRISPR-Cas9 era, scientists have known that the first step in how it edits genomes — snipping ...
Viewpoint: ‘Worrisome conflicts’ created by lack of diversity in biotech research funding
You exit a cramped, hazy subway car with a throng of professionals. As you emerge blinking into Kendall Square in ...
Will Africa embrace CRISPR gene editing and the next phase of the biotech revolution?
Scientists around the world are increasingly turning to the promise of CRISPR gene editing to tackle any number of problems ...
Editing the brain? CRISPR and gold nanoparticles could make it possible
Add this to the list of possible applications for the seemingly-magical gene editing technology CRISPR: helping people with neurological disorders edit ...
Who will CRISPR benefit? How to prevent this life-saving technology from creating gender and geographical disparities
From cancer to malaria to HIV, CRISPR is set to open up all kinds of dramatic breakthroughs in medicine, as ...
Resurrecting the northern white rhino and other lost species. But at what cost?
Time has been called on the northern white rhinoceros, but this call is already being challenged. When the last male ...
Does CRISPR cause unintended mutations? Not in this monkey study
CRISPR is still new, and no one really knows its potential side effects. Does it cause cancer? How about unintended mutations? To get ...
Predicting the risk of heart disease using CRISPR and stem cells
In our human genome, there are many elusive genetic variants related to medical conditions, but the impact of these variants to ...
Can we treat autism with CRISPR gene editing?
Scientists have figured how to use a form of the powerful gene-editing tool CRISPR to erase genetic traits normally associated ...
Meet Francisco Mojica, the scientist who first discovered CRISPR in a Spanish salt marsh
Professor [Francisco] Mojica grew up near the Mediterranean port of Santa Pola in Spain, a region famous for its salt ...
Fueling CRISPR: The nonprofit dedicated to sharing ‘bits of useful DNA’
When Feng Zhang was a graduate student in the early 2000s, he helped make a groundbreaking discovery: Light-sensitive proteins from ...
With gene drives, we could delete’ an entire invasive species. Should we?
In a windowless London basement, behind three sets of locked steel doors and a wall of glass, thousands of Anopheles gambiae mosquitoes cling ...
Using CRISPR to build a ‘massive library’ of tools to cure genetic disease
In the past few years, [David] Liu’s become one of the most brightly-shining luminaries in the rapidly advancing field of gene ...
Using CRISPR to block production of HIV in infected cells
Contracting HIV is no longer the death sentence that it was in the 1980s and early 90s. The first cases ...
What we need to know about reports suggesting CRISPR can cause cancer
STAT’s story about CRISPR-edited cells often lacking a functional gene known to prevent cancer caused a bit of a stir... Cut to ...
CRISPR legal battle front: UC Berkeley wins pair of patents
There’s been a legal battle going on to determine which of the scientists whose research led to CRISPR’s discovery gets ...
Will CRISPR gene editing disrupt or perpetuate global health and medical social inequalities?
On [June 3 and 4], hundreds of scientists, industry folk, and public health officials from all over the world filled ...
Fears of ‘designer babies’ are surfacing again
"What we're seeing is a fast slide down a very slippery slope toward designer babies," warned Marcy Darnovsky. … What has alarmed ...
