Human Gene Editing
‘Just because we can do it, should we?’ How CRISPR co-creator Jennifer Doudna is furthering the discussion over the ethics of human genome editing
In 2012, Jennifer Doudna, then a relatively unknown biochemist at the University of California Berkeley, published a paper with Emmanuelle Charpentier ...
Podcast: ‘Regenerative’ farming—a green fad; Gene-edited bacteria destroy tumors; Banana-flavored beer
So-called "regenerative" farming is gaining traction as a method of sustainable food production. Does it live up to the hype ...
‘Obesity is way more complex than we thought’: Risk of being overweight likely influenced by what happened in the womb
Obesity can seriously compromise a person’s physical and mental health. It is definedTrusted Source as “abnormal or excessive fat accumulation ...
CRISPR cryptography: Making the world safer from gene-editing research gone awry
Evolution is Kevin Esvelt’s passion: how it works in nature, how we can direct it, and how it can go ...
New treatments for rare, inherited childhood diseases? CRISPR sheep help advance research
A flock of gene-edited sheep has been used by scientists to pinpoint a promising treatment for a lethal inherited brain ...
A CRISPR cure for HIV? Gene-editing technology may be able stop viral replication in its tracks and wipe out infections
In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to ...
‘Near-limitless CRISPR therapies’: This drug delivery breakthrough helps gene editing technology infiltrate cells
A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future ...
Gene therapy approvals now at four with treatments for inherited anemia and degenerative brain condition — but costs are stratospheric. Why?
The FDA recently approved two gene therapies with hefty price tags, the first for an inherited anemia and the second ...
10-year CRISPR anniversary: How gene editing revolutionized medicine, and what lies ahead
Ten years ago, a little-known Science paper authored by Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D., proposed using CRISPR/Cas9 for gene editing ...
‘When we exercise, we’re not just doing it for ourselves’: Why going on a run today could benefit your future grandkids
Exercising now is good for you. But could it also be good for your future children and grandchildren? ...
CRISPR co-creator Emmanuelle Charpentier: ‘Studying microbes can solve some of the biggest problems facing humanity, including how our metabolisms and brains work’
In early September, CRISPR co-creator Emmanuelle Charpentier traveled to Yerevan, Armenia to be one of the main speakers at the ...
New reversible gene-editing technique may be safer and more reliable than standard CRISPR
Chinese researchers say they have developed a new gene-editing tool that is more efficient and safer because it does not ...
Moonshot genomics: How CRISPR is opening the door to reshaping life itself
It’s a moonshot idea. If the genome is a book, gene editing is like copy editing—changing a typo here and ...
Could there ever be a vaccine for breast cancer?
Triple-negative breast cancer, about 10% of all breast cancers, is one of the most aggressive and deadliest forms of this ...
Novel gene therapy study offers hope for definitive colorblindness cure
Researchers from the University College London (UCL) used gene therapy to partly restore the function of the retina's cone receptors ...
Duchenne muscular dystrophy (DMD): Background on the first personalized CRISPR therapy approved for trial
The FDA has given the greenlight to test the first personalized CRISPR therapy, which was developed specifically to treat one ...
$2.8 million Zynteglo gene therapy: Bluebird sets price on one-time beta-thalassemia treatment replacing red blood cell transfusions
Zynteglo has become the first cell-based gene therapy to be approved in the US, getting the nod from the FDA ...
Why resurrecting near-replicas of extinct woolly mammoths might work
Woolly mammoths, the iconic giants of the last ice age, went extinct around 4,000 years ago. But one company is ...
‘Engineering safety’: How we can improve CRISPR for wider use in medicine and agriculture
I run a research lab at the University of Pittsburgh where we focus on developing tools that can control the ...
Do you have high cholesterol? With gene editing, there soon may be a CRISPR cure
A trial testing a new CRISPR-based treatment to lower cholesterol has officially kicked off in New Zealand. If it works ...
Could CRISPR gene editing raise cancer risks?
It was a groundbreaking development a decade ago: CRISPR gene-editing technology that allows the snipping of DNA to remove undesired ...
Viewpoint: Advocacy group opposed to human heritable gene editing claims vast social and political dangers ahead
CRISPR and other methods of gene editing have captured the public imagination, spurring countless lectures, articles, and think pieces about ...
CRISPR vs mRNA: Excision and Moderna battle for genetic therapy for HIV
Moderna and Excision BioTherapeutics are stepping into a battle with HIV, a 41-year epidemic that has confuddled drug developers and ...
The gene-edited CRISPR twins are growing up — raising questions about the ethics of continuing to study them
More than a billion people live in China, but researchers in the country have proposed the creation of a healthcare ...
CRISPR may not always be safe: Study finds gene editing can damage genome and in extreme cases cause cancer
Scientists at Tel Aviv University (TAU) warn that while the CRISPR genome-editing method is very effective, it is not always safe and ...
How one CRISPR-tweaked gene could permanently lower cholesterol
A volunteer in New Zealand has become the first person to undergo DNA editing in order to lower their blood ...
Viewpoint: Shining future promised by gene therapy blocked by researchers who refuse to share data
Transparency in gene therapy research — which can be accomplished without compromising commercial prospects — is vital to success. One ...