FDA details risk-based cellular therapy and regenerative medicine guidelines

FDA details risk-based cellular therapy and regenerative medicine guidelines

The FDA has issued two final guidances and two draft guidances, all designed to articulate the agency’s approach to developing ...
How epigenetics is linked to drug resistance

How epigenetics is linked to drug resistance

Scientists at Vanderbilt University say they have discovered a nongenetic cause of resistance to cetuximab, a therapeutic that is used ...
Big data meets CRISPR: 'Cloud biology' platform could speed up gene editing crop improvement

Big data meets CRISPR: ‘Cloud biology’ platform could speed up gene editing crop improvement

Benson Hill Biosystems, an agricultural technology company, reports the launch of Edit, which is powered by CropOS™, a computational platform ...
GMO soybean oil causes less obesity in mice than conventional oil

GMO soybean oil causes less obesity in mice than conventional oil

Long-term tests in mice indicate that a genetically modified (GM) brand of soybean oil causes less obesity and insulin resistance ...
Genetic cancer screenings based on family history may not go far enough

Genetic cancer screenings based on family history may not go far enough

Simultaneous sequencing of tumor DNA and normal tissue for a broad panel of cancer-related genes may detect more potentially clinically ...
Why don't two people with the same illness suffer equally? It's genetic

Why don’t two people with the same illness suffer equally? It’s genetic

Ever wonder why your friend, co-worker, or partner doesn’t get as sick as you, even though they caught the same ...
Sunburn savior? High doses of vitamin D may jumpstart skin repair

Sunburn savior? High doses of vitamin D may jumpstart skin repair

Anyone who has ever had bad sunburn understands the agonizing discomfort associated with too much sun exposure and would probably ...
Reversing Huntington's? Brain shown to heal itself after disease source edited out -- in mice

Reversing Huntington’s? Brain shown to heal itself after disease source edited out — in mice

The potential of genome-editing techniques, such as CRISPR/Cas9, to alleviate disease burden has ignited the imagination for thousands of researchers ...
Patients with ALS, other neurological disorders look to gene-silencing drug for hope

Patients with ALS, other neurological disorders look to gene-silencing drug for hope

Two recent mouse studies, led by investigators at the University of Utah and Stanford University, describe how a new antisense ...
Tiny CRISPR-Cas9 injections could treat retinal diseases, with no off-target effects

Tiny CRISPR-Cas9 injections could treat retinal diseases, with no off-target effects

Scientists at the Center for Genome Engineering, within the Institute for Basic Science (IBS) in Korea, in collaboration with ToolGen, ...
Personality genes correlate with psychiatric disorders

Personality genes correlate with psychiatric disorders

Nature vs. nurture has been a long-standing argument between the fields of biology and psychology. However...investigators have identified six loci ...

Scientists discover virus that steals CRISPR machinery from bacteria

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Viruses have often been ...

Genes point to potential treatments for digestive diseases

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Scientists at the University ...
If not anti-science, what’s in the heads and hearts of GMO opponents?

If not anti-science, what’s in the heads and hearts of GMO opponents?

For years, supporters and opponents of genetically-modified organisms (GMOs) have debated questions ranging from the safety of engineered crops, to ...

Sexual reproduction is good for the human genome

Theories on the genetic advantages of sexual reproduction abound within the biological sciences community, but there has been scant evidence ...

Light-activated genes in bacteria engineered with CRISPR-Cas9

Scientists may have taken a step closer to making science fiction a medical reality. Researchers at Duke University have developed ...

Hormone therapeutics boosted by unique cow antibodies

The friendly cow, said to be blown by all the winds that pass, and wet with all the showers, may ...

How oncologists sort through masses of genetic data

Whether they are concerned with a mutation of a single gene, or mutations in a combination of two or more ...

More potential health benefits found from drinking red wine

Researchers at Texas A&M Health Science Center College of Medicine report that a compound found in common foods such as ...

Motion sickness? Genes might be to blame

Breathe deep and look at the horizon. It’s the sagely advice many of us have heard who experience motion sickness, ...

Epigenetic markers predict mortality better than biological age

Chemical changes to DNA that accumulate over a lifetime amount to a kind of biological clock. By analyzing these changes, ...

Gene editing, CRISPR, might provide solution to viral antibiotic resistance

A gene editing system bacteria use to shield themselves from viruses has been used by MIT scientists as a sword to vanquish ...

All tumors should be genotyped. Why aren’t they?

There are huge benefits to genomic tumor assessment, both for better treatment now, and later, if first-line treatments fail. But ...

Stem cell dysfunction may be responsible in some cases of schizophrenia

A gene long associated with schizophrenia and subsequently studied in rodent brain has now been scrutinized in human neurons. These neurons, derived ...

‘Subway’ map tracks journey of engineered stem cells

The differentiation of engineered stem cells may be imagined as a subway journey, where the genetic equivalents of missing a transfer or ...

Scientists apply century-old technique to shrink tumors using bacteria

Inspired by hundred-year-old accounts of how bacterial infections coincided with cancer remissions, scientists have shown that injections of a weakened bacterium — Clostridium ...

Can cancers be categorized more precisely?

Advancing the work of The Cancer Genome Atlas (TCGA), a large team of researchers from multiple institutions performed a comprehensive analysis of ...

Canadian scientists develop new, quicker technique for genomic analysis

Scientists from McGill University and the Génome Québec Innovation Centre say they have achieved a technical advance that could result in speedier ...