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Why 2018 might not be a banner year for CRISPR gene editing in humans

Emily Mullin | MIT Technology Review | 
Ever since scientists first used CRISPR-Cas9 to edit living human cells in 2013, they’ve been saying that the possibilities for ...
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Will new wave of gene-edited crops ease public fear of GMO food?

Antonio Regalado | MIT Technology Review | 
To many scientists, the potential of gene editing seems nearly limitless, offering a new way to rapidly create plants that ...
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California cherry farmers look to ‘gene drive’ technology to kill invasive fruit flies

Antonio Regalado | MIT Technology Review | 
Since it first appeared in Northern California in 2008, the spotted-wing drosophila, a type of fruit fly native to Asia, ...
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‘Semi-synthetic’ organism expands DNA base alphabet

Antonio Regalado | MIT Technology Review | 
Every living thing on Earth stores the instructions for life as DNA, using the four genetic bases A, G, C, ...
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Why life-saving gene therapy isn’t available yet to children who need it most

Emily Mullin | MIT Technology Review | 
[The first patient to permanently edit his DNA,] Brian Madeux, 44, of Arizona, is part of a clinical trial testing ...
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How gene therapy could help fight methamphetamine addiction

Emily Mullin | MIT Technology Review | 
Gene therapy, which modifies a person’s DNA, has long been thought of as a way to treat genetic diseases—and, more recently, ...
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CRISPR 2.0 ‘base editing’ arrives and it’s an even more remarkable disease-fighting tool

Emilly Mullin | MIT Technology Review | 
You’ve probably heard of the molecular scalpel CRISPR-Cas9, which can edit or delete whole genes. Now, scientists have developed a ...
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Why personal genetics company Helix sparks intense criticism

Antonio Regalado | MIT Technology Review | 
It can’t be good when America’s most famous cardiologist, one with 114,000 Twitter followers, posts to social media that your ...
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Non-browning genetically engineered ‘Arctic apples’ now on sale–without GMO label

Andrew Rosenblum | MIT Technology Review | 
[Arctic] apples are genetically altered to suppress browning and may be offered for sale as bagged slices in up to ...
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Inserting CRISPR machinery into human cells to fight Huntington’s and Lou Gehrig’s

Emily Mullin | MIT Technology Review | 
The gene-editing tool CRISPR is based on a natural defense system embedded in bacterial cells that recognizes and destroys invading ...
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Has the evolution of artificial intelligence reached its limits?

James Somers | MIT Technology Review | 
But the peculiar thing about deep learning is just how old its key ideas are. Hinton’s breakthrough paper...was published in ...
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Synthetic bionics: E. coli pills could boost body’s ability to absorb ammonia in the gut

Antonio Regalado | MIT Technology Review | 
Synlogic of Cambridge, Massachusetts, the company behind the unusual study, is testing what it calls “synthetic biotics,” or bacteria engineered ...
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CRISPR ear injections repair genetic hearing loss in mice

Antonio Regalado | MIT Technology Review | 
We all know that CRISPR is the next big thing in gene-editing treatments. But how do you get the versatile genetic scissors ...
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Edible ‘CRISPR pill’ could make harmful bacteria self-destruct

Emily Mullin | MIT Technology Review | 
As resistance to antibiotics grows in the U.S., researchers are looking for new ways to fight germs like Clostridium difficile, a ...
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Human embryoids push bioethical boundaries

Antonio Regalado | MIT Technology Review | 
Scientists are using stem cells to create clumps of cells that increasingly resemble bits of brain, lungs, or intestine. […] ...
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$500K gene therapy treatment? Some see a bargain

Emily Mullin | MIT Technology Review | 
The idea behind gene therapy is that genetic material is used as a “living drug” to treat disease. Scientists have been ...
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Mini ‘brains’ aid study of dementia and mental illness

Russ Juskalian | MIT Technology Review | 
[A] brain organoid begins as a single skin cell taken from an adult. With the right biochemical prodding, that cell ...
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Calculating odds of destroying humanity with genetic engineering

MIT Technology Review | 
How likely is it that humanity will destroy itself? Various scientists have studied this probability, and the basic calculation is ...
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Muscular dystrophy ‘death sentence’ targeted by gene therapy trials

Antonio Regalado | MIT Technology Review | 
[T]hree U.S. teams say they are ready to try to treat Duchenne [Muscular Dystrophy] with gene therapy. The first study ...
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How GM seeds can ‘push’ photosynthesis to improve yields, battle impact of climate change

To feed a growing population, the United Nations projects, worldwide agricultural yields must increase by 50 percent between now and ...
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5 companies leading the personal genomics revolution

Emily Mullin | MIT Technology Review | 
As gene sequencing technology gets faster and cheaper, companies are finding more ways to commercialize DNA, from offering disease-specific genetic ...
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Hacking frontier? Corrupted DNA used to seize control of computer

Antonio Regalado | MIT Technology Review | 
In what appears to be the first successful hack of a software program using DNA, researchers say malware they incorporated ...
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US first: CRISPR-edited human embryos

Steve Connor | MIT Technology Review | 
The first known attempt at creating genetically modified human embryos in the United States has been carried out by a ...
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What’s next in consumer genetics? Helix’s ‘app store for your genome’

Emily Mullin | MIT Technology Review | 
A Silicon Valley startup called Helix is betting on the notion that not only do people want to learn more ...
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How connecting our brain to a computer could restore lost sight or hearing

Adam Piore | MIT Technology Review | 
Matt Angle’s claim might have sounded eccentric before: for years, he insisted that the key to solving one of neuroscience’s ...
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US biotech seed patents linked to increasing corn yields

MIT Technology Review | 
[Mariam Barry at ENSTA ParisTech in France and colleagues] have studied the yield of hybrid corn in the U.S. since 1985 ...
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Darwin Life: ‘Three-parent babies’ as a cure for age-related infertility

Emily Mullin | MIT Technology Review | 
John Zhang, a U.S. fertility doctor has started a company [called Darwin Life] with a provocative vision for older women: become ...
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China syndrome: Genome sequencing gives parents a glimpse of their babies’ genetic risks—for a price

A Boston-based DNA sequencing company is offering to decode the complete genomes of newborns in China, leading some to ask ...
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