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Why did 5 leukemia patients die in 2016 CAR-T trial?

Roni Dengler | Science | 
More than a year after five leukemia patients died from an experimental treatment involving genetically engineered immune cells, its developer ...
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How choosing genetically similar partners shapes our genomes

Ann Gibbons | Science | 
Chances are, you’re going to marry someone a lot like you. Similar intelligence, similar height, similar body weight. A new ...
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Checkpoint inhibitors fight cancer–but can have nasty side effects

Jennifer Couzin-Frankel | Science | 
Yale University immunologist Kevan Herold spoke about a few of his newest diabetes patients to an unlikely audience: oncologists and ...
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Dog genome project: How your breed originated

Elizabeth Pennisi | Science | 
From the 80-kilogram Great Dane to the 1-kilogram tiny teacup poodle, there seems to be a dog for everyone. Now, ...
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Cost effective? What DNA screening might catch that we are not likely to find

Bijal Trivedi | Science | 
Known broadly as the MyCode Community Health Initiative and run by the Danville-based Geisinger Health System, the effort has so ...
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Ancient incompatibility: Why human females and Neanderthal males had difficulty conceiving

Ann Gibbons | Science | 
After years of sequencing the genomes of female Neandertals, researchers have finally got their first good look at the Y ...
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Neanderthal-human mating reintroduced lost African genes, for better and worse

Ann Gibbons | Science | 
When Neandertals mated with modern humans, they shared more than an intimate moment and their own DNA. They also gave ...
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Ancient ‘Tianyuan man’ is full-fledged Homo sapiens

Ann Gibbons | Science | 
When scientists excavated a 40,000-year-old skeleton in China in 2003, they thought they had discovered the offspring of a Neandertal and ...
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What do your Neanderthal genes do?

Ann Gibbons | Science | 
By sequencing a remarkably complete genome from a 50,000-year-old bone fragment of a female Neandertal found in Vindija Cave in ...
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Video: Evolution at work–RNA in New York City mice has changed so they can eat fast food

Science | 
With all its hustle, bustle, concrete, and congestion, they say New York City changes people. And that may be true, ...
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Antibiotic use on farms could be cut by up to 80 percent globally, study finds

Almost 80% of all antibiotics in the United States aren’t taken by people. They’re given to cows, pigs, and chickens ...
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Why New Guinea islanders are among the most genetically diverse people in the world

Ann Gibbons | Science | 
If you travel the meandering Sepik River of New Guinea, it quickly becomes apparent that from one bend to the ...
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Multiple sclerosis added to list of diseases exacerbated by gut microbes

Giorgia Gugliemi | Science | 
The trillions of bacteria that live in our intestines, known collectively as the gut microbiome, have been linked to maladies ...
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Activist witch hunt? PETA targets Yale postdoc researcher known for progressive research on bird stress

David Grimm | Science | 
It started in May with a web post by People for the Ethical Treatment of Animals (PETA). “Tell Yale University to Stop ...
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Drug that reverses diabetes and obesity in mice may strengthen brittle bones

Emma Yasinski | Science | 
A drug that can reverse diabetes and obesity in mice may have an unexpected benefit: strengthening bones. Experiments with a ...
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‘Breakthrough’ treatment for PTSD? FDA approves ecstasy drug trial

Kai Kupferschmidt | Science | 
One of the main targets in the war on drugs could well become a drug to treat the scars of ...
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Heart attack risk could be significantly reduced with simple anti-inflammatory medication

Jennifer Couzin-Frankel | Science | 
A clinical trial of more than 10,000 heart attack patients supports a novel way to protect them from a stroke ...
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Americans shedding their skepticism of human genome editing

Jon Cohen | Science | 
Earlier surveys of Americans (here and here) have found a reluctance to support human genome editing...But the new survey, conducted by social ...
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Could vitamin B3 supplements prevent birth defects?

Gretchen Vogel | Science | 
An extra dose of vitamin B3 might help prevent certain kinds of complex birth defects, according to a new study ...
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End of allergies? Researchers identify cells that trigger reactions

Mitch Leslie | Science | 
Allergies stem from mistaken identity, when some of our immune cells respond to benign substances—known as allergens—that include pollen, mold ...
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Plant breeders call for sharing university seed patents to spur crop research, innovation

Virginia Gewin | Science | 
Universities need to get better at sharing patented seeds and other products of publicly-funded agricultural science if the United States ...
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Antisocial bees could aid the study of autism in humans

Elizabeth Pennisi | Science | 
A new study reveals that [antisocial bees] share a genetic profile with people who have autism spectrum disorders, which can ...
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Zika tragedy reanimates ethical and medical debate about vaccines for pregnant women

Jon Cohen | Science | 
Ever since the shocking realization in 1961 that the morning sickness pill thalidomide caused shortened limbs in babies, doctors have ...
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Who invented CRISPR gene editing: Broad Institute v University of California patent battle intensifies

Jon Cohen | Science | 
The University of California (UC) has fired another legal salvo in the prolonged patent battle over CRISPR, the revolutionary gene-editing ...
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Chemist Derek Lowe: Panera Bread spreads misinformation on chemicals and food—yet again

Derek Lowe | Science | 
[Editor's note: Derek Lowe is a Duke University-trained organic chemist.] [S]everal people alerted me to one of the latest ads ...
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Dog-human bonding: Genetic mutations for Williams syndrome may explain canine friendliness

Elizabeth Pennisi | Science | 
Using clues from humans with a genetic disorder that makes them unusually friendly, [researchers Monique Udell and Bridgett vonHoldt] found ...
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Surviving the cure: Stem cell transplant that saved a patient’s life now poses mortal threat

Jon Cohen | Science | 
A few months before completing medical school in 2003, Lukas Wartman was diagnosed with acute lymphoblastic leukemia (ALL), a blood ...
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Ray of life: Did sunlight kickstart Earth’s biological transformation?

Roland Pease | Science | 
A new study suggests that the iron-and-sulfur clusters at the heart of many life-critical enzymes could have been floating around ...
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