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Adverse reactions in COVID-19 vaccine trial illustrates rocky road to developing therapies for diverse populations

Matthew Herper | STAT&nbsp|&nbsp
Patients in clinical trials are usually faceless. But as the experimental Covid-19 vaccine being developed by Moderna Therapeutics has begun ...
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Viewpoint: We can’t simply test our way out of the coronavirus pandemic

Michael Hochman | STAT&nbsp|&nbsp
In response to calls for Covid-19 testing of the entire U.S. population, several large universities, and even some employers, have ...
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Experimental Parkinson’s treatment draws ethics scrutiny with wealthy donor selected as first patient

Sharon Begley | STAT&nbsp|&nbsp
A secretive experiment revealed [May 12], in which neurosurgeons transplanted brain cells into a patient with Parkinson’s disease, made medical ...
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Pandemic could give a boost to remote-monitoring devices that keep patients out of the doctor’s office

Erin Brodwin | STAT&nbsp|&nbsp
It was a shift that began long before the pandemic: Tech companies, health providers, and patients alike were increasingly looking ...
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‘This is what it feels like to be normal’: Experimental stem cell treatment shows promise against Parkinson’s

Sharon Begley | STAT&nbsp|&nbsp
[Researchers planned] to carry out an experimental transplant surgery unprecedented in the annals of medicine: replacing the dysfunctional brain cells ...
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There will be no vaccine widely available by fall (or anytime soon) even with a miracle breakthrough

Helen Branswell | STAT&nbsp|&nbsp
Vaccines to prevent Covid-19 infection are hurtling through development at speeds never before seen. But mounting promises that some vaccine ...
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What the porn industry can teach us about how to live safely with coronavirus

Usha McFarling | STAT&nbsp|&nbsp
Since the late 1990s, when an outbreak of HIV infections threatened to shutter the multibillion-dollar industry, the mainstream porn community ...
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Is this brain-controlled prosthetic arm—with the sensation of touch—the future of prosthetics?

Shafaq Zia | STAT&nbsp|&nbsp
[T]hree years ago, [electrician Rickard] Normark received a new kind of brain-controlled prosthetic that was surgically attached to the bone, ...
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‘Impenetrable medical jargon’: Why retooling ClinicalTrials.gov should be a priority

Alison Bateman-House, Jamie Webb | STAT&nbsp|&nbsp
Millions of people visit ClinicalTrials.gov each year to find a trial that they or a loved one might be eligible ...
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Viewpoint: US failure to ‘study drugs more quickly’ means more people are dying from coronavirus

Matthew Herper | STAT&nbsp|&nbsp
When medical historians look back at the Covid-19 pandemic, they will reckon with how the United States, with its vast ...
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Using artificial intelligence to identify promising coronavirus treatments

Casey Ross | STAT&nbsp|&nbsp
Treating patients with the never-before-seen Covid-19 is forcing doctors to choose between two equally unpalatable options: try an unproven therapy ...
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Gilead’s remdesivir offers little benefit for coronavirus patients in early trial

Adam Feuerstein, Ed Silverman, Matthew Herper | STAT&nbsp|&nbsp
The antiviral medicine remdesivir from Gilead Sciences failed to speed the improvement of patients with Covid-19 or prevent them from ...
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When will experimental coronavirus drugs will be ready for the clinic?

Matthew Herper | STAT&nbsp|&nbsp
Is there hope that something will be available soon to help us fight this virus, known as SARS-CoV-2? Here’s a ...
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Dark side of CRISPR: Rogue scientists could design something nastier than the coronavirus

Neal Baer | STAT&nbsp|&nbsp
When we’ve emerged on the other side of the pandemic, Covid-19 will someday make a good story. But I worry ...
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Dealing with ‘confusing directives’, US doctors seek coronavirus advice from Chinese counterparts

Sharon Begley | STAT&nbsp|&nbsp
Now, fed up with what they see as inadequate and confusing directives from public health authorities, many physicians are trying ...
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CRISPR pioneer Jennifer Doudna turns lab into coronavirus test center

Matthew Herper | STAT&nbsp|&nbsp
A team of academic and industry researchers led by Jennifer Doudna, the researcher best known for her role in the ...
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Viewpoint: We’re making big decisions on the coronavirus without solid data

John Ioannidis | STAT&nbsp|&nbsp
At a time when everyone needs better information, from disease modelers and governments to people quarantined or just social distancing, ...
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Coronavirus immunotherapy could arrive by early summer. Is ‘record time’ fast enough?

Maggie Fox | STAT&nbsp|&nbsp
Blood-plasma-based cures aren’t just the stuff of movies. There’s plenty of science to back the idea that blood products from ...
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Some countries have done a much better job fighting the coronavirus. Here’s what worked.

Helen Branswell | STAT&nbsp|&nbsp
With Europe and the United States locked in deadly battle with the coronavirus that causes Covid-19, a number of countries ...
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Hunting for DNA signatures in blood could offer early warning system for cancer

Rebecca Robbins | STAT&nbsp|&nbsp
The many companies developing liquid biopsies to try to detect cancer early have so far largely mined the blood in ...
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Viewpoint: Promise of genomics and precision medicine a ‘wave of hype without substance’

Nigel Paneth, Richard Cooper | STAT&nbsp|&nbsp
An undeclared civil war is breaking out in biomedicine. On one side is precision medicine, with its emphasis on tailoring treatments ...
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Viewpoint: Embracing biosimilars will drive down prices, increase access to drugs

Sean McGowan | STAT&nbsp|&nbsp
The biosimilar category holds incredible promise, and the market for these products is on an upward trajectory. But it’s been ...
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There was an opioid epidemic 130 years ago. Can it teach us anything about today’s crisis?

Haider Warraich | STAT&nbsp|&nbsp
The 1890s and 1990s were both characterized by unopposed amplification of the benefits of opioids, the transformation of physicians into ...
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Viewpoint: 4 ways the FDA must evolve to deal with fast-moving technologies and health threats

Ellen Sigal, Mark McClellan | STAT&nbsp|&nbsp
As we look toward the FDA of the 2020s that can achieve further progress in addressing urgent health threats and ...
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Is the quest for profits getting in the way of ending the HIV epidemic?

Douglas Krakower, Julia Marcus, Kenneth Katz | STAT&nbsp|&nbsp
Four decades after the HIV epidemic began, there’s finally hope it might end. Indeed, “Getting to Zero” — meaning zero ...
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Those childhood vaccinations for tetanus and diphtheria should cover you for life, study says

Elizabeth Cooney | STAT&nbsp|&nbsp
People who got all their vaccinations against tetanus and diphtheria in childhood don’t need booster shots to remain protected against ...
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Seeking new momentum in Alzheimer’s research after decades of slow progress

Andrew Joseph | STAT&nbsp|&nbsp
5.8 million Americans have Alzheimer’s, with a new person developing the condition about every minute of every day. There is still ...
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‘A real mystery’: Why hasn’t anyone attempted to make a cloned human baby?

Henry Greely | STAT&nbsp|&nbsp
For nearly seven years, then, the scientific community has had solid proof that human embryos can be cloned. ...  So ...
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