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Paying for pricey gene therapy without insurance: Amish community faces challenge

Eric Boodman | STAT | 
[A]t $850,000 a person, Luxturna was more budget-busting than just about any other drug. [Company] Spark had proposed a few different ways of helping ...
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Autism test that appears to work for monkeys may open research doors for humans

Andrew Joseph | STAT | 
Researchers have been left empty-handed so far in their quest to uncover some measurable biological signal that could be used ...
GENOME master

Can we recode the human genome to resist viruses?

Sharon Begley | STAT | 
[T]wo years in, an ambitious project to synthesize genomes — including human ones — is moving on from its shaky ...
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CRISPR patent dispute is back in court. What should we expect?

Sharon Begley | STAT | 
It’s baaaaack, that reputation-shredding, stock-moving fight to the death over key CRISPR patents. On [April 30] in Washington, D.C., the ...
brca genetic testing

23andMe founder Anne Wojcicki: No need for experts to interpret direct-to-consumer breast and ovarian cancer tests

Anne Wojcicki | STAT | 
My company, 23andMe, recently received FDA authorization for the first ever direct-to-consumer genetic test for an inherited risk for cancer. Specifically, it tests for ...
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Video: How genetics is revolutionizing medicine and disease research

Sharon Begley | STAT | 
This three-part series of documentary shorts, produced by Retro Report in partnership with STAT, looks back at the roots of three of ...
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Highly anticipated Luxturna gene therapy for blindness costs $850,000

Eric Boodman | STAT | 
The trouble had started over a decade ago, when the Hogans noticed something wasn’t right with their son Jack...When they ...
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Viewpoint: GlaxoSmithKline abandonment of rare disease gene-therapy drug program because it’s not a money generator hurts children

Maria Kefalis | STAT | 
When GlaxoSmithKline, long a global leader in the effort to pioneer gene replacement therapies, announced it would halt its drug ...
crispr

CRISPR update calms fears about off-target editing effects

Sharon Begley | STAT | 
The fear that CRISPR-based genome repair for preventing or treating genetic diseases will be derailed by “editing gone wild” has ...
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Reconstructing genome of ancient bird opens door to reviving lost species

Sharon Begley | STAT | 
Scientists at Harvard University have assembled the first nearly complete genome of the little bush moa, a flightless bird that ...
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Promiscuous bacterial ‘sex’ plays role in antibiotic resistance

T. Schindler | STAT | 
Bacteria and fungi created natural antibiotics eons before drug companies turned them into medicines. To counter these natural microbe killers, ...
crispr

CRISPR as a ‘medical sleuth’: Gene-editing tool could detect Zika, Ebola and cancer

Sharon Begley | STAT | 
Some of the world’s leading CRISPR labs have, independently, tweaked CRISPR — adding bursts of light here and rings of ...
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Harnessing bacteria like E. coli to dispense medicines shows promise, but hurdles remain

Drew Smith | STAT | 
We’ve already seen the first cellular medicines, human immune cells genetically reprogrammed to attack cancer cells. Now the first bacterial medicines ...
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Precision CRISPR repairs blindness in mice, could herald human treatments

Sharon Begley | STAT | 
In genome-editing, the challenge for CRISPR-wielding scientists is to edit only one of the two copies, or alleles, of every ...
Lupus

This may explain why women are more likely to develop lupus

Andrew Joseph | STAT | 
Every year, 16,000 cases of lupus are reported in the United States — 9 out of 10 of them in women. Scientists ...
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Broken barrier: Monkeys are first primates to be cloned

Sharon Begley | STAT | 
There have been mice and cows and pigs and camels, bunnies and bantengs and ferrets and dogs, but ever since ...
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Are ‘incredible genes’ protecting President Trump’s health?

Sharon Begley | STAT | 
Unless someone swipes one of President Trump’s used forks from the Mar-a-Lago dining room and sends it to 23andMe for ...
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Why this winter’s flu is wreaking so much havoc

Helen Branswell | STAT | 
To put it flatly, H3N2 is the problem child of seasonal flu. It causes more deaths than the other influenza ...
gene therapy

Report: Price for blindness gene therapy Luxturna is ‘four times too high’ at $850,000

Andrew Joseph | STAT | 
The $850,000 list price for a new medicine that treats a genetic form of childhood blindness is about four times too high ...
crispr

CRISPR setback? Our immune system may attack the treatment used with the popular gene editor

Andrew Joseph | STAT | 
A new paper points to a previously unknown hurdle for scientists racing to develop therapies using the revolutionary genome-editing tool ...
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Birth defects in Brazil linked to Zika, not insecticides or vaccines

Helen Branswell | STAT | 
In the fall and early winter of 2015, a startling number of infants in northeastern Brazil were born with abnormally small ...
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Mars missions: What would long-term space travel do to the brain?

Sharon Begley | STAT | 
In a NASA-funded study published on [November 1], Dr. Donna Roberts of the Medical University of South Carolina and her ...
bigstock sperm injection

IVF ethics: What if your only viable embryo has a genetic disease?

Andrew Joseph | STAT | 
[A]n emerging ethical morass in the field of reproductive medicine: what to do when patients seeking to get pregnant select ...
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Controversial DNA test company Proove Biosciences forced to restructure

Charles Piller | STAT | 
Proove Biosciences, a formerly high-flying genetic testing firm whose science and business practices have been challenged by experts and former employees, has ...
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Zika vaccine now seen as unlikely, as project dropped

Helen Branswell | STAT | 
Vaccine giant Sanofi Pasteur has quietly pulled the plug on its Zika vaccine project, a move that underscores how difficult ...
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‘Futuristic star’: The scientist growing transplantable human organs in pigs

Usha McFarling | STAT | 
Juan Carlos Izpisua Belmonte had spent years probing the inner workings of embryos, ferreting out the genes that give a ...
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White supremacists flock to genetic tests to confirm their ‘purity’—but most find they have mixed racial ancestries

Eric Boodman | STAT | 
With the rise of spit-in-a-cup genetic testing, there’s a trend of white nationalists using these services to prove their racial ...
Thomas van Ardenne

Having trouble conceiving? A new genetic test might help

Rebecca Robbins | STAT | 
More than 50 doctors have already ordered [the Fertilome test] for hundreds of women seeking scientific guidance on questions such as whether ...
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