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Understanding how ketamine helps the brain deal with depression

Ruairi Mackenzie | 
The promise of ketamine, an anesthetic drug primarily used at sub-anesthetic doses to either manage severe pain or send recreational ...
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Can virtual reality treat depression symptoms through ‘pleasant scenarios’?

Megan Thielking | 
Michelle Craske is asking patients to dive into coral reefs, ride on bullet trains rushing past pine trees, and cheer ...
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Searching for genetic links to suicidal thoughts and behavior

Rona Strawbridge | 
New genetic research could help identify those most at risk of suicide ...
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This funny-looking helmet could treat depression by ‘rewiring’ the brain

James Hamblin | 
[Recent] weeks have been frenetic for Bre Hushaw, who is now known to millions of people as the girl in ...
4-18-2019 a doctor explains how prescribing ketamine for depression works

Ketamine for depression—what we know about how it changes the brain

Simon Makin | 
The FDA's approval [of ketamine for depression] marks the first genuinely new type of psychiatric drug—for any condition—to be brought ...
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Why esketamine will force doctors to rethink office visits for depressed patients

Amitha Kalaichandran | 
The Food and Drug Administration approved esketamine (Spravato) for treatment-resistant depression to be administered under physician supervision. It’s a derivative of ...
4-4-2019 ct hlth dna tests antidepressants

Can genetic testing pinpoint the right antidepressant, or is it just ‘a shot in the dark’?

Ilana Marcus | 
For patients who weren’t responding well after trying one or two different antidepressants, [physician Jeremy Bruce] started sending samples of ...
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Exercise can fight depression, but it doesn’t work for everyone

Jill Adams | 
Is there evidence to support the idea that exercise can have an effect on depression? And if so, how much ...
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Viewpoint: Esketamine promises to boost depression treatments—but we don’t know enough about long-term effects

Laura Sanders | 
With great fanfare, a new antidepressant entered the U.S. market in March [2019], the first fundamentally new medicine for depression ...
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Vulnerability to mental illness may have given humans an evolutionary advantage

Dana Smith | 
Nearly one in five Americans currently suffers from a mental illness, and roughly half of us will be diagnosed with ...
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Why psychiatrists should stop ‘looking the other way’ when confronted with faked mental illness

Jacob Appel | 
The act of feigning illness for personal gain, or malingering, is far more widespread than the public might suspect ...
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‘Game-changing’ drug first ever postpartum depression medication approved by FDA

Adam Feuerstein | 
The Food and Drug Administration on [March 19] approved brexanolone, the first drug specifically targeted to treat postpartum depression — ...
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‘Good Reasons for Bad Feelings’: Understanding evolution’s role in anxiety, depression and making us human

Adrian Woolfson | 
[In] the thought-provoking Good Reasons for Bad Feelings, [evolutionary] psychiatrist Randolph Nesse offers insights that radically reframe psychiatric conditions. In his ...
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‘Suicide’ headaches? Magic mushrooms or LSD could offer relief

David Warmflash | 
Hallucinogenic drugs, particularly lysergic acid diethylamide (LSD) and psilocybin, are classified as Schedule 1, but scientists and physicians believe they ...
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Esketamine touted as ‘game changer’ for depression—but who gets to use it?

Ed Cara | 
[Recently,] the Food and Drug Administration approved Johnson & Johnson’s Spravato, the nasal spray version of a ketamine-like sedative, for ...
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Esketamine nasal spray, touted as biggest advance in years for treating depression, gets FDA approval

Carolyn Johnson, Laurie McGinley | 
The Food and Drug Administration approved a novel antidepressant late Tuesday [March 5] for people with depression that does not ...
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70% of teens see mental health, depression as a ‘major struggle’ for their generation in Pew survey

Amanda Mull | 
In the past decade, young people in the United States have borne the brunt of some of the most highly ...
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Nearly half of major depression episodes could be prevented, studies show

Ricardo Muñoz | 
While there are many effective treatments for depression, including medications and psychological therapies, the rate of depression is not going ...
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Brain implants could soon join fight against severe depression

Laura Sanders | 
With powerful computational methods, scientists have recently zeroed in on some key features of depressed brains. Those hallmarks include certain ...
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Fighting depression: Nasal-based ketamine spray clears key FDA hurdle

Ed Cara | 
One of the largest hurdles to ketamine becoming a mainstream depression treatment may have just been cleared. On [February 12], ...
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Early diagnosis of children with anxiety, depression key to better treatment

Sujata Gupta | 
Researchers wanted to see if the movements during a scary situation differed between children diagnosed with depression or anxiety and ...
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Is depression affected by bacteria in the gut?

Jane Recker | 
The human microbiome—a collection of bacteria, archaea, fungi and viruses commingling in the gut and intestines—has been linked to a ...
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Autism and depression: Study shows why ‘gold standard treatment’ sometimes fails

Kristen Hovet | 
The 'gold standard' therapy does not always work and can lead to a worsening of symptoms ...
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Treating depression with brain-stimulating implants

Ed Cara | 
[A] new study out of the University of California, San Francisco, published [November 29] in Current Biology, seems to offer an intriguing ...
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You sound down: Using AI to spot depression in a person’s voice

Randy Rieland | 
[T]he notion that artificial intelligence could help predict if a person is suffering from depression is potentially a big step ...
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The stuff that ‘makes magic mushrooms so magic’ moves closer to FDA approval for treating depression

Ed Cara | 
The active ingredient that makes magic mushrooms so magic—the psychedelic drug psilocybin—is one step closer to becoming a legal treatment for ...
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