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Does popular antipsychotic drug Abilify cause ‘uncontrollable urges’ to gamble, eat and have sex?

Megan Thielking | 
By the time she stopped taking aripiprazole — an antipsychotic sold under the brand name Abilify — [Denise Miley had] ...
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Video: How does the brain act on what it sees?

Jaclyn Jeffrey-Wilensky | 
What we see often determines how we act: We hit the brakes if a car is stopped ahead of us ...
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Study sparks fresh debate over an old theory on the cause of Alzheimer’s

Damian Garde | 
In the long-running debate over just what causes Alzheimer’s disease, one side looks to have scored a victory with new ...
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Investigational Alzheimer’s drug shows promise

Damian Garde | 
An investigational Alzheimer’s drug significantly slowed patients’ cognitive decline in a large clinical trial, unexpected and unprecedented results that could ...
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Examining the legacy of W. French Anderson—’father of gene therapy’ and convicted child molester

Sharon Begley | 
[Dr. W. French] Anderson has been hailed as the father of gene therapy and was honored at George H.W. Bush’s ...
Reproductive medicine could become entangled in the 'embryos are people' debate

Reproductive medicine could become entangled in the ’embryos are people’ debate

Eric Forman | 
The announcement that Supreme Court Justice Anthony Kennedy will retire at the end of [July] and President Trump’s nomination of ...
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Inside the battle to convince insurers that chronic fatigue syndrome is a legitimate illness

Dave Tuller, Steven Lubet | 
[Reporter Brian Vastag’s career] came to an end in July 2012, when he found himself afflicted by a mysterious and ...
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Duchenne muscular dystrophy gene therapy trial put on hold

Kate Sheridan | 
Sarepta Therapeutics’ clinical trial for a gene therapy to treat Duchenne muscular dystrophy has been paused by the Food and ...
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Video: Inside the quest to truly understand the living cell

Jeffrey Delviscio | 
“I would be happy to have a rudimentary understanding of a single cell.” That doesn’t sound like a shocking statement, ...
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How do we know if probiotics are safe if studies don’t report risks?

Megan Thielking | 
As consumer interest grows in probiotics and other supplements that claim to regulate gut microbes, experts are posing a critical ...
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Drugmakers accused of stalling biosimilars: FDA’s Gottlieb calls tactics ‘a toxin’

Erin Mershon | 
Food and Drug Administration Commissioner Scott Gottlieb on Wednesday [July 18] accused drug makers who manufacture pricey biologic medicines of ...
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FDA releases guidelines to fast-track new generation of fast-acting antidepressants

Megan Thielking | 
As companies race to develop fast-acting antidepressants, they are grappling with how to design clinical trials for a type of ...
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‘Scientific gold rush’ created by quest for universal immunotherapy

Damian Garde | 
The drug industry has made a mint on immunotherapies for cancer, but those game-changing treatments don’t work for most people’s tumors ...
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‘Wake-up call’? CRISPR gene editing may cause ‘genetic havoc’, study suggests

Sharon Begley | 
From the earliest days of the CRISPR-Cas9 era, scientists have known that the first step in how it edits genomes — snipping ...
depression

Patients with suicidal thoughts can be included in depression clinical trials, FDA says

Megan Thielking | 
The Food and Drug Administration is overhauling its guidance for developing treatments for major depressive disorder for the first time ...
cancer

Adaptive Oncogenesis: Alternative to ‘brute force’ cancer cures, which often leave patients severely damaged

James DeGregori | 
In Darwinian evolution, organisms that are well-adapted to their environments flourish and crowd out those that aren’t. My colleagues and ...
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Immunotherapy can provide ‘spectacular results’. But how effective is it for the elderly?

Ankur Parikh | 
Immunotherapy is effective against a variety of cancers, with sometimes spectacular results. But I worry about how effective it is in ...
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Viewpoint: We need better access to genetic tests to fulfill the promise of precision medicine

Chadi Nabhan | 
[E]ven as innovative targeted [cancer] therapies become available, various barriers prevent patients from gaining access to them. One hurdle that ...
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Mixing psychiatry and neurology: This doctor treats patients other doctors have given up on

Eric Boodman | 
[Neuroscientist Alice Flaherty] has been toying with the boundaries of illness itself. She likes seeing patients other doctors have given ...
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Key question facing new gene therapy for blood disorders: How long will it last?

Adam Feurstein | 
New versions of Bluebird Bio’s gene therapy for inherited blood disorders yielded significant benefits for patients, according to updated results from ...
pharma

Biosimilar market creates rift in drug industry known for its solidarity

Erin Mershon | 
The pharmaceutical industry’s massive lobbying operation has a well-earned reputation for maintaining a united front on most of the major ...
all of us

Viewpoint: Why you should give your DNA to NIH’s ‘All of Us’ initiative

Eric Dishman | 
The National Institutes of Health recently launched the All of Us Research Program to create one of the largest, richest public resources for biomedical ...
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First marijuana-based drug gets nod from FDA for 2 forms of epilepsy

Andrew Joseph | 
The Food and Drug Administration on Monday [June 25] approved the country’s first drug derived from marijuana, a medication that ...
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FDA changing policy on how best to spur development of biosimilar drugs that resemble brand-name biologics

Ed Silverman | 
In an unusual step, the Food and Drug Administration withdrew a draft guidance that was issued last fall to help companies develop ...
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Privacy concerns? Genetic testing companies pressed by US lawmakers

Megan Thielking | 
Pressure is growing on direct-to-consumer genealogy and genetic testing companies to be more transparent about their privacy policies, after the ...
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Fighting disease, not making money, focus of new Gates Foundation biotech institute

Helen Branswell | 
There’s a new biotech in town. And it doesn’t care about making money. The Bill and Melinda Gates Foundation has ...
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What we need to know about reports suggesting CRISPR can cause cancer

Sharon Begley | 
STAT’s story about CRISPR-edited cells often lacking a functional gene known to prevent cancer caused a bit of a stir... Cut to ...
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