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GLP podcast: Assessing the Cass report; Fetal genome surgery could treat disease during pregnancy; How ‘body-tracking data’ threatens privacy

Cameron English, Liza Dunn | 
The recently released Cass report has intensified an already ferocious debate over gender-affirming care for children. What are the key ...
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AI and CRISPR converge: Artificial intelligence generates gene editing blueprints to solve host of previously untreatable diseases

Cade Metz | 
Generative A.I. technologies can write poetry and computer programs or create images of teddy bears and videos of cartoon characters that look like something from a ...
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Companies race to achieve pig kidney transplants. Who will be first to convince the world their technologies are safest?

Lisa Jarvis | 
Xenotransplantation, the futuristic sounding field of animal-to-human organ transplants, is suddenly a lot closer to reality. The first two gene-edited ...
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‘Go for it’: Dozens of people on the brink of death put faith in controversial ‘in vivo’ CRISPR gene therapy treatments

Betsy McKay | 
Regulators last year approved the world’s first medicine using Crispr, the Nobel Prize-winning tool for modifying genes ...
Saving human lives: Using gene therapy to cure diseases in the womb

Saving human lives: Using gene therapy and fetal surgery to cure diseases in the womb

Megan Molteni | 
The convergence of these technologies into a whole new field of medicine dedicated to curing diseases before birth: fetal genome ...
What did pre-Christian Chinese Emperor Wu look like? Genetic analysis creates 3D face reconstruction

What did sixth-century Chinese Emperor Wu look like? Genetic analysis creates 3D face reconstruction

Hui Qiao, Kongyang Zhu, Panxin Du | 
A team of researchers has successfully generated a genome of the Chinese Emperor Wu (Wudi) of the Xianbei-led Northern Zhou ...
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Viewpoint: Scientific community puts pressure on Germany to repeal law blocking reproductive technology and research on embryos

Isabelle Bartram | 
The scientific community is launching a renewed attack on the controversial law of the German Embryo Protection Act ...
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Infographic: Could gut bacteria help us diagnose and treat diseases? This is on the horizon thanks to CRISPR gene editing

Humans are never alone. Even in a room devoid of other people, they are always in the company of billions ...
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Viewpoint: Using CRISPR to cure diseases is an ethical tightrope — Here’s a Jewish perspective

Lucas Besterman | 
CRISPR has the potential to treat or even cure a gamut of inherited diseases which have long evaded researchers ...
Viewpoint: Hunting cloned sheep? What weird things might happen as our bio-engineering skills improve

Viewpoint: Hunting cloned sheep? What weird things might happen as our bio-engineering skills improve?

Pete Shanks | 
Some people — not just Montanans — pay to indulge in “captive hunting,” and large sheep make excellent targets ...
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‘Miracle’ sickle cell cure limits ability to have children: What are the options?

Gerry Smith | 
When Celenise Mahmood first learned about two new gene therapies that could cure sickle cell disease, she felt a wave ...
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Leading ways CRISPR is being honed to cure and prevent disease

Robert Smith | 
Talented researchers are exploring ways of using CRISPR to edit genes by cutting and pasting any desired DNA sequence ...
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GLP podcast: RFK Jr. recycles ‘gay frogs’ pesticide conspiracy; GMO v organic debate is over; Scientist behind gene-edited twins back in the lab

Cameron English, Liza Dunn | 
RFK, Jr. has resurrected the long-debunked speculation that atrazine, a low-toxicity weedkiller, causes sexual dysphoria in frogs—and humans. The oft-reported ...
Challenging bioethical taboos: Chinese scientist He Jiankui who modified the genes of human embryos to protect them from HIV reopens his lab

Challenging bioethical taboos: Chinese scientist He Jiankui who modified the genes of human embryos to protect them from HIV reopens his lab

Chinese researcher He Jiankui revealed to the Mainichi Shimbun that he has resumed research on human embryo genome editing ...
World’s first genetically engineered pig kidney transplant into a living patient is a major step in addressing global organ shortage

World’s first genetically engineered pig kidney transplant into living patient is major step towards addressing global organ shortage

A biotechnology company developing human-compatible engineered organs announced the first ever transplantation ...
Making human eggs out of skin cells could change everything for infertile mothers or same sex parents. Here’s where the technology is today

Making human eggs out of skin cells could change everything for infertile mothers or same sex parents. Here’s where the technology is today

Ian Sample | 
New procedure could overcome common forms of infertility and help people have children who share their DNA ...
The ‘weird, wild, wonderful, and downright unsettling’ ways researchers are using mini organs

The ‘weird, wild, wonderful, and downright unsettling’ ways researchers are using mini organs

Cassandra Willyard | 
Scientists are using organoids to screen drug candidates, grow viruses, build biocomputers, and much, much more ...
CRISPR co-creator Jennifer Doudna on how gene editing can tackle antibiotic resistance crisis

CRISPR co-creator Jennifer Doudna on how gene editing can tackle antibiotic resistance crisis

Understanding how CRISPR could be used to tackle antibiotic resistance, we need to understand how that resistance arises in the ...
What do Muslim leaders have to say about ethics of germline editing to prevent diseases?

What do Muslim leaders have to say about ethics of germline editing to prevent diseases?

Dr Sayyed Mohamed Muhsin and Dr Alexis Heng Boon Chin give ethical analysis of germline genome editing based on Islamic ...
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‘People are going to be better-looking, healthier and smarter – what’s not to like?’ What are the pitfalls of selecting embryos for intelligence?

Sienna Rodgers | 
The second age of eugenics: Would you select an embryo according to its chances of higher intelligence? And is that ...
Gene therapy has restored hearing for a second child. Here’s why some deaf people adamantly oppose treatment

Gene therapy has restored hearing for a second child. Here’s why some deaf people adamantly oppose treatment

Tom Avril | 
Children's Hospital of Philadelphia surgeon John Germiller was among the world's first to successfully treat a deaf child with gene ...
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Unique use of CRISPR gene editing is paving the way to treat cancer

Christy Brownlee | 
New gene-editing approach to studying immune gene function could improve treatments for cancer, other diseases ...
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Probiotics are ‘enticing target’ for gene editing — but is CRISPR up for the challenge?

Ricki Lewis | 
Every morning I pop a Pearl probiotic. I try hard not to drop it, for the tiny, slippery yellow sphere ...
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100,000 Americans are waiting for transplants. Could pig-grown organs close this gap?

Jen Christensen | 
The need for more transplant organs is immense and some scientists think animal organs might be a good way to ...
Acne treatment of the future: Gene-editing the bacteria that lives on your skin

Acne treatment of the future: Gene-editing the bacteria that lives on your skin

An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to ...
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‘There is no sound I don’t like’ — In gene editing breakthrough, Lilly’s 30-day gene therapy restores hearing of 11-year old boy, with more deafness treatments on the way

Gina Kolata | 
The genetic treatment targeted a particular kind of congenital deafness and will soon be tried in children who are younger ...
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$3 million barrier to sickle cell gene therapy: How prohibitive costs could limit practical benefits of newly-approved drugs

Katie Hasson | 
In a much-anticipated move, the Federal Drug Administration (FDA) has approved two new gene therapies for sickle cell disease ...
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