Biotechnology is vital to Africa’s strategic interests

Global food politics is riddled with paradoxes. While threats to global food security are becoming increasingly evident, efforts to stall the adoption of new technologies appear to intensify.

There is a clear disconnect between comfort with familiar agricultural practices and the food challenges that lie ahead. Though food is recognized as a national security issue, it has yet to acquire the strategic importance it deserves, especially in African countries. The lack of strategic thinking underlies many of the poor decisions that many African countries make regarding agricultural biotechnology.

The world food outlook for 2013 has been the subject of grim forecasts based on evidence of drought in the United States and other regions of the world. But amid these concerns countries such as Kenya have taken the unusual decision to ban the importation of genetically modified (GM) food pending further information on their safety.

 

View the original article here: Commentary – Biotechnology and Africa’s strategic interests

Cheerios removes app during fury of anti-GMO backlash

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Cheerios just faced a humiliating public relations failure thanks to the undiscriminating nature of free speech through social media.

Just a few days ago, Cheerios (General Mills) released an app on Facebook asking ‘fans’ to gratefully show what Cheerios means to them. Users could write their own sentiments by placing Cheerios’ iconic black font over a yellow template, complete with little cheerios for periods and dots.

The app was yanked after only one day when their Facebook page (and photo album associated with the app) was flooded with a torrent of anti-GMO messages from angry consumers.

View the original article here: Activist Post: Cheerios Removes App During Fury of Anti-GMO Backlash

Darwin and eugenics

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My last few posts on eugenics has generated a debate that others might find interesting. Eugenics is the attempt to breed humans using Darwinian principles. But many Darwinists today try to disassociate Darwin with the social applications of his theory, especially because of the Nazi experience. This is part 1 of the ongoing debate over Darwin and eugenics. More is coming later. Thank you, dear readers, for caring about what Darwin really thought and the implications this has for us today. Ideas have consequences.

View the original article here: Debate Over Darwin and Eugenics Continues: Part 1 – Christian Post (blog)

Genome sequencing for babies brings knowledge and conflicts

Genome sequencing deciphers an individual’s entire genetic code. The price of doing this has been dropping quickly, raising the possibility that sequencing can become more common than ever before. That includes the possibility of sequencing all babies when they’re born. This raises serious ethical questions about the potential harm knowledge can bring.

View the original article here: Genome Sequencing For Babies Brings Knowledge And Conflicts

Genomics revolution: UK could miss the boat, scientists warn

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The UK has a huge opportunity to lead the world in disease discovery, treatments and cures. But support from the NHS and better data collection is needed if Britain is not to lose out in the coming genomics revolution, leading scientists believe.

View the original article here: Genomics revolution: UK could miss the boat, scientists warn

Mixed views on Myriad after Supreme Court agrees to rehear case

NEW YORK – Wall Street analysts took a mixed view of Myriad Genetics today following the announcement on Friday by the US Supreme Court that it would review a lawsuit challenging the company’s patents related to the BRCA1 and BRCA2 genes.

View the original article here: Analysts Provide Mixed Views on Myriad After Supreme Court Agrees to Rehear Patent Case

Genetic screening: Do you really want to know what might eventually kill you?

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Americans spend more than $5 billion annually on genetic testing for everything from Alzheimer’s to breast cancer to Huntington’s disease, and the list is growing. What are the consequences for carrying a gene for an incurable disease? That knowledge, some scientists say, could ruin the life you have now.

Additional Resources:

  • “Genome Sequencing For Babies Brings Knowledge And Conflicts,” WNYC

View the original article here: A need to know the worst news you will ever hear

Groundbreaking stem cell surgery earns backlash

Tommie Prins, 32, from Milnerton, told the Cape Argus last week he was “honoured” to be the first known patient to receive the transplant in South Africa. He had been paralysed while on a holiday on the Garden Route six years ago, when he plunged into the ocean, hit a sandbank and broke his neck. Now, since operations at Melomed Private Hospital by Franschhoek-based neurosurgeon Adriaan Liebenberg on October 10 and 24, an extraordinary recovery had begun.

The doctor who performed groundbreaking stem-cell transplants on a quadriplegic patient has been slammed by two professional bodies.

View the original article here: Stem cell surgery dispute

Anti-GMO hoax targets Kaiser-Permanente health group

Last night, a large number of web sites proudly announced that the Kaiser-Permanente health group had advised its subscribers to avoid GMO foods. We first became aware of this when the somewhat flakey web site Fooducate  posted this announcement. The article, and hundred like it on other “natural foods websites” all posted a fuzzy low resolution scan of what purported to be a bulletin from Kaiser advising against the use of GMO foods.

There are two problems with the announcement:

  • The science is complete nonsense.
  • Kaiser didn’t say anything of the sort.

View the original article here: Huge GMO hoax targets Kaiser-Permanente

Kenya’s ban on GM foods is a big blow to biotech research

Research institutions, Universities and consumers are biggest losers in a new directive by the Government to ban trade and importation of genetically modified foods (GMOs), experts say.

Moi, Kenyatta, Jomo Kenyatta University of Agriculture and Technology (JKUAT) and Nairobi universities have been laying foundation for biotechnology studies. For instance, Kenyatta University had review existing biochemistry and biotechnology programs to take advantage of recent legislation passed by the Government in support of GMOs.

Read the original article here: Big blow to biotechnology research as Kenya bans GM foods

Childhood trauma leaves mark on DNA of some victims

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma. In individuals with a genetic predisposition, trauma causes long-term changes in DNA methylation leading to a lasting dysregulation of the stress hormone system. As a result, those affected find themselves less able to cope with stressful situations throughout their lives, frequently leading to depression, post-traumatic stress disorder or anxiety disorders in adulthood.
 
Doctors and scientists hope these discoveries will yield new treatment strategies tailored to individual patients, as well as increased public awareness of the importance of protecting children from trauma and its consequences.

Supreme Court to decide whether human genes can be patented

The U.S. Supreme Court agreed to hear, for a second time, a lawsuit challenging patents held by Myriad Genetics on human genes implicated in breast cancer.

The court, in an order today, said it would consider only the question of whether human genes can be patented, meaning it plans to dive straight into one of the most contentious — and elusive — questions in patent law, which is the difference between an invention and a natural phenomena. Opponents of the patents say they prevent researchers from even examining naturally occurring genetic material that companies have patented. Supporters say the law allows patents on any process that isolates a valuable substance, even if it’s naturally occurring, citing industrial processes to create useful products out of hydrocarbons and plant material.

View the original article here: Supreme Court To Decide If Human Genes Can Be Patented In Myriad Case

India: The growing doubt over GM crops

[T]he central character of Indian agriculture, the farmer, is a pitiable picture, with the burdens of ever increasing cost of cultivation, over-dependence on industry for agricultural inputs and lack of adequate government policy support. Unfortunately for the Indian farmer, real long term sustainable solutions are a blur because the agro input industry and their cronies in the government use every opportunity to push through false solutions that are only profitable to the companies and not the farmer. One such delusional solution is the herbicide tolerant (HT) genetically modified (GM) crops marketed by multinational biotech seed companies as a one-stop shop for weed management. On the contrary, herbicide-tolerant genetically modified crops are disastrous for India’s socioeconomic framework.

View the original article here: The growing doubt over GM crops

Dr. Oz “denigrates” organic consumers

In Time magazine, Dr. Mehmet Oz, who once told millions of viewers, “I want you to eat organic foods” and “your kids deserve better than to be part of a national chemistry experiment,” has seemingly changed his tune and turned the decision to buy organic foods into a political and class issue. 

Not only did Dr. Oz write that conventional foods are nutritionally equal to organic foods (he never mentions pesticide contamination), he calls organic foods “elitist.”  Suddenly, a middle-class mother who decides to pay extra for a safe haven from pesticide contamination is called “snooty” and a “food snob” by the very same celebrity physician who once urged her to protect her children from agricultural chemicals by choosing organic. 

View the original article here: Organic: Food Justice for the 99% (Response to Time Magazine/Dr. Oz denigration of organic consumers)

Are genetically modified crops finally on their way out of India?

Predictably, the recommendation by an experts’ panel appointed by the Supreme Court  – that trials of genetically modified (GM) crops should be halted for 10 years – has stirred a hornet’s nest. Such a moratorium would include ongoing trials and the court rejected it.

This follows on the heels of the Parliamentary Standing Committee on Agriculture’s 492-page report published in August which asked for the banning of GM food crops in the country. The Supreme Court set up the expert panel shorty after the report was published. The Court is set to let its ruling known, very soon.

View the original article here: Are genetically modified crops finally on their way out of India?

India’s GM food hypocrisy

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India has enjoyed signal successes with genetic engineering in agriculture. But today the nation’s relationship with this critical biotechnology is in total disarray, the victim of activists’ scaremongering and government pandering. Perhaps reason will win out in the face of such absurdities, and officials will come to their senses. Until then, the irony of India’s fear and ignorance driven approach to genetic engineering is that the only Frankenstein’s monster it has spawned is bureaucracy run amok.

Additional Resources:

 View the original article here: India’s GM Food Hypocrisy

[If the WSJ pay-wall stops you, you can also read the article here and here.]

Defeated anti-GMO coalition resurrected as GMO Inside

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goldfishDefeated at the polls in California, anti-GM forces behind Proposition 37 have resurrected their campaign under the moniker GMO Inside. And they’ve come out guns blazing, backing a lawsuit that claims Goldfish crackers shouldn’t be labeled as “natural” because they contain genetically engineered soybean oil.

GMO Inside appears to be a rebranding of the coalition that lost 52-47% in November. The GMO Inside’s steering committee include many of the same organizations behind the California initiative: Green America, Food Democracy Now!, Nature’s Path, Nutiva and even the scientifically discredited Institute for Responsible Technology.

All of the same campaign elements of the original effort appear intact. They are demanding that all raw or processed foods offered for sale to consumers be labeled if its genetic material has been altered in a laboratory process and the banning of advertising of any transgenic food as “natural”. They are promoting the new effort on Facebook and Twitter.

Their first post-defeat initiative was an attack on Thanksgiving—a news release warning consumers to screen their turkey spread to make certain that genetically modified foods would not be “an unwelcome and hidden guest at your Thanksgiving celebration.” What if you had already bought a food with GM ingredients, which is almost a certainty? “[Y]ou can print GMO’ labels, place them on food, photograph and upload the photo to social media to warn family and friends,” suggested GMO Inside

The campaign strikes the same strident chords that turned off many California voters. Alisa Gravitz, CEO of Green America, which is the point NGO on the new effort, blamed their defeat on “corporate America” and accused corporations for using consumers as “lab rats” for genetically engineered foods.

The new website slams specific companies and products as being “suspect for GMOs” and provides lists of supposedly known non-GMO alternatives. Rick Keller, an agriculture reporter, notes that GMO Inside echoes the “don’t let a friend drive drunk” campaign by telling the public to warn their friends and families of GMO ingredient products—don’t let friends eat GMOs. “The suggestion is to use social media to post product pictures of those thought to have GMO ingredients,” he writes.

gmoTheir first viral attack came last week against Cheerios, which has a long-running Facebook promotion. General Mills launched a new “app” on their page allowing fans to post their thoughts about the cereal, which like most cereals contains genetically modified ingredents. GMO Inside jumped on the opportunity, launching a counter campaign urging anti-GMO activists to post negative comments on the company page—which is now filled with anti-GMO diatribes.

GMO opponents have also doubled down on their favorite weapon: litigation. This time they are targeting Pepperidge Farm, Inc., owned by Campbell Soup. A class action, filed in federal court in Colorado, alleges that Pepperidge Farm “has mistakenly or misleadingly represented that its Cheddar Goldfish crackers … are ‘Natural,’ when in fact, they are not, because they contain Genetically Modified Organisms … in the form of soy and/or soy derivatives.”  

The California initiative would have banned bioengineered foods from being labeled as natural, but the language of Prop 37 was so sloppy that almost all foods made with soy oil—perhaps the most popular oil used in the food industry—would have been prevented from using the word.

A hidden battle here, as an editorial in the Los Angeles Times notes, is over the word “natural.” Ben & Jerry’s ice cream, a GMO opponent and a favorite of anti-GMO activists, was forced to drop the world “natural” from its label because its ice cream contained, among other things, partially hydrogenated soybean oil, which is made through a chemical process and has been implicated as an artery-clogging ingredient to be avoided. In contrast, there is no evidence that genetically engineered foods pose any harm to human health and there has not been one reputable study that suggests any harm is likely.

The U.S. Food and Drug Administration has never defined the term “natural” and has only stepped in when it’s used to describe products containing artificial coloring, flavoring or “synthetic substances.” Although it did not refer to Prop 37 directly, the FDA has said that a labeling policy like the initiative would be “inherently misleading.”

 Should the FDA change course based on the simple idea of a “right to know,” as anti-GMO activists contend? Biofortied, the most prominent blog in the Green Genes” movement that promotes the sustainable qualities of genetically modified crops and foods, has deconstructed that perspective. Safety, contends Rob Hebert, has always been the main labeling concern of the FDA. The agency determined it had no reason to single out bioengineered foods for special labeling because recombinant DNA techniques were really just extensions of traditional methods for developing new plant varieties–such as hybridization–which had not received special attention in the past. Curiosity alone shouldn’t be enough to spur new FDA labeling requirements, he wrote:

First, it places an enormous financial burden on industries that would have to investigate, document, and label the “level” of bioengineering that went into their product; second, it may mislead consumers into thinking that bioengineered crops are somehow less safe than their conventional counterparts; third, it places a burden on the FDA itself which must then divert efforts from safety labeling issues to consumer curiosity labeling issues; and fourth, it places no end on the information that consumers could require manufacturers to disclose

Additional Resources:

GMO Inside News Release

• Natural Products Insider

• Don’t Be a Lab Rat

Goldfish Suit

Sarah Fecht is a writer and editor at the Genetic Literacy Project.

Jon Entine is executive director of the Genetic Literacy Project and senior fellow at the Center for Health & Risk Communication at George Mason University.

Embryos for sale

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For those who have struggled with the emotional, physical, and monetary stresses of trying unsuccessfully to start a family by using other people’s eggs or sperm, there is another option: embryo donation. According to Jessica Cussins, some doctors may be crossing cross ethical lines.

Read more

Disease tracking direct-to-consumer genome sequencing breaks $1000 barrier ($695)

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Whole genome sequencing, (also known as full genome sequencing, complete genome sequencing, or entire genome sequencing), is a laboratory process that maps a person’s complete genetic code. Because the data that is produced can be staggeringly large—there are approximately six billion base pairs in each human genome—genomic data crunching requires a large amount of computing power and storage capacity and can cost tens of thousands of dollars (down from more than a billion dollars a decade ago).

That’s why it’s been used mostly for research. But rapid developments in sequencing technology in recent years have brought down the cost dramatically, and that technology is now being introduced to consumers. The new focus is what is called exome sequencing, which is the subset of our DNA that codes for proteins.

In a riveting article last month in Time, Bonnie Rochman tells the story of Adam Foye, an 11 year old boy whose symptoms match up with centronuclear myopathy (CNM), a rare muscle disease, but genetic testing shows no signs of abnormalities in any gene linked to CNM. The hope is that through exome sequencing, the genetic mutations causing his condition can be identified opening the door to a possible treatment.

The research on Adam is being coordinated through Boston Children’s Hospital, but soon consumers will have tools at their own disposal. Gene By Gene, better known as the parent company of the popular genetic genealogy provider Family Tree DNA, has launched a new division, DNA DTC, to offer what it claims is “highly reliable and competitively priced genomic testing solutions.” Although it also offers whole genome sequencing, it’s key product is “utilizing next generation sequencing including the entire exome (at 80x coverage)” for an introductory price of $695 at 80x coverage. It will also sequence whole genomes for $5,495.

Why is this a breakthrough? Dan Vorhaus, an expert in genetics and the law and author of Genomics Law Report, notes that this is a significant extension of the “direct-to-consumer” genetic testing market. According to Vorhaus: “23andMe, the acknowledged market leader in DTC genetic testing, employs the same DTC model, but it’s exome pilot product ($999) continues to remain closed to new customers and the company does not (yet) offer a whole genome sequencing service. Thus, DNA DTC appears to be the only company currently offering a truly DTC whole exome or whole genome product.”

DNA DTC is unique in its offering because it is only selling the raw data rather than an interpretation of the data, specifically noting, “data analysis not included.” Genome analysis is complicated though there is disagreement about how expensive it will be as the process becomes increasingly automated.

FDADNA DTC certainly has its eye on the Food and Drug Administration. As Vorhaus notes, “while the FDA has indicated at intervals in the past few years that it intends to more closely scrutinize the DTC genetic testing industry, the FDA has never suggested – nor do I think it likely – that the agency intends to turn its regulatory gaze upon providers of raw genetic or genomic data.”

Vorhaus does raise concerns that DNA DTC, based on its privacy policy, is technically entitled to share its customers’ genomic information without specific and informed consent, but it’s likely that represents an unintentional ambiguity in the wording, and the company says it has no plans to market the data.

While 23andMe is holding back its product, seeking premarket approval from the FDA to provide interpretation of sequenced data, DNA DTC is blazing ahead, going direct to the consumer with a raw product—with the expectation, it’s assumed, that third parties will emerge to offer analysis at a reasonable price. How big is the market? It’s too early to say.

As Vorhaus notes, it’s a sign of healthy innovation in a still very young business—five years old this month—and an indication of how vital the industry can be if regulators give it room to breathe.

Jon Entine, executive director of the Genetic Literacy Project, is senior fellow at the Center for Health & Risk Communication and at STATS at George Mason University.

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