CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to ...
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Endometriosis relief: Breakthrough treatment for severe cases on the horizon using epigenetics

[Scientists from Michigan State University] pharmacologically inhibited P300, a protein implicated in the dysregulation of endometrial epithelial cells, which normally ...
Epigenetics finding completely upends our understanding of drug addiction

Epigenetics finding completely upends our understanding of drug addiction

I was taught to scoff at Jean-Baptiste Lamarck and his theory that traits acquired through life experience could be passed on to ...
Brain aging and dementia remain a mystery. This epigenetic model may help unravel it

Brain aging and dementia remain a mystery. This epigenetic model may help unravel it

People age at different rates, with some individuals developing both characteristics and diseases related to aging earlier in life than ...
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‘Disease-cancelling technology’: New drugs may act more like noise-control headphones

Rather than focusing on the DNA and proteins involved in a disease, Immuneering focuses on disease-associated gene signaling and expression ...
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High-yielding plants that survive temperature swings may be our next weapon against climate change

Sally Mackenzie spent her childhood summers walking through the vast fields of bright, red, ripe tomato crops: They grow best ...
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Childhood trauma: The kids are not alright, and part of the explanation may be linked to epigenetics

The old adage about kids being resilient and able to bounce back from early traumas isn't necessarily borne out by ...
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Epigenetics mystery: Can environment-induced changes be passed on?

Israeli researchers have discovered that laboratory worms transfer information about their parents’ physical environment through small RNA molecules that occur ...
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Podcast: Rebel Cell: Cancer, evolution and the science of life

Geneticist Dr Kat Arney brings you exclusive excerpts from her new book Rebel Cell, exploring where cancer came from, where ...
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Podcast: The surprising science of epigenetics—How a family of ‘Mickey Mouse mice’ overturned our understanding of heredity

Kat Arney takes a look at the world of epigenetics, finding out if more than DNA passes on to the ...
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How old is that child? ‘Epigenetic clocks’ could help fight child labor, trafficking and improve age records on immigrant children

Epigenetic clocks are a new type of biological test currently capturing the attention of the scientific community, private companies and ...
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Can we ‘program’ people through epigenetics to enjoy exercise?

Some people wake early every morning to run, bike, swim, or lift. For others, finding the motivation to work out ...
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‘Elixir of life’: Can epigenetic reprogramming help us live longer and healthier?

[Juan Carlos]  Izpisúa Belmonte can rejuvenate aging, dying animals. He can rewind time. But just as quickly as he blows ...
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Video: What does it mean to ‘turn on’ a gene?

In the murky darkness, blue and green blobs are dancing. Sometimes they keep decorous distances from each other, but other ...
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Epigenetics could alter the way we breed crops for drought and climate change

New techniques allow researchers to change the way crops behave and handle adverse conditions--without actually altering the plants' underlying DNA ...
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Can frequent exercise epigenetically slow the aging process?

Research under way in Melbourne is showing that exercise can, literally, make your body younger. … [Researcher Sarah] Voisin tells ...
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New techniques could transform epigenetics research, ameliorating diseases

Epigenetics, the study of mechanisms by which genes are turned on or off without altering their genetic code or DNA ...
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How a father’s stresses alter sperm and can ‘leave his children scarred’

A stressed-out and traumatized father can leave scars in his children. New research suggests this happens because sperm “learn” paternal ...
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Epigenetic clues could assist crime investigations by revealing age range, lifestyle habits of suspects

[The] field of forensic epigenetics [uses] the markers that sit on top of DNA and modify it’s expression, rather than the ...
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How can seemingly-unique animals be genetically the same?

More and more, biologists are discovering that organisms thought to be different species are, in fact, but one. A recent ...
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Relationship between genes and obesity could be altered by what we eat

A correlation between obesity and genetics has been found to be modified by diet, according to a scientific paper in ...
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Viewpoint: Here’s why the controversial field of epigenetics is ‘so alluring’

I think of stories I’ve been told about my grandmother in 1945 Japan. … It feels plausible, and poetic, to ...
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Is epigenetics the ‘secret superpower’ of invasive species?

Due to the small numbers that are introduced, invasive species experience a genetic bottleneck that results in low levels of ...
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Hatchery-raised vs wild-born coho salmon: Containment sites may alter epigenome, hurting survival in the wild

[Biologist Louis Bernatchez of Quebec’s Laval University] and his colleagues set out to search for evidence of a different kind of hatchery adaptation, ...
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Adding 24 new mutations to breast cancer risk calculations

Twenty-four previously unknown mutations that raise a woman's risk of developing breast cancer have been identified by scientists. The 'ground-breaking' findings [February ...
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Epigenetics of exercise: Our muscles appear to have ‘molecular memory’

Our muscles may actually possess a molecular memory in the form of epigenetic marks on our DNA. According to a ...
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