10-9-2018 5bbcac0ba4cb621aba692be3-960-720

Treating genetic disorders before birth? CRISPR cures mouse disease in the womb

Nearly 40 years after surgeons first operated on fetuses to cure devastating abnormalities, researchers have taken the first step toward curing genetic ...
Japan poised to permit gene editing on human embryos by 2019

Japan poised to permit gene editing on human embryos by 2019

Japan has issued draft guidelines that allow the use of gene-editing tools in human embryos. The proposal was released by ...
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Mosquito massacre: Can we safely tackle malaria with a CRISPR gene drive?

CRISPR-Cas9 gene editing quickly decimated two caged populations of malaria-bearing mosquitoes (Anopheles gambiae) in a recent study, introducing a new ...
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Creating a safer CRISPR by targeting RNA instead of DNA

Researchers at the prestigious Salk Institute are reporting that they have managed to map the molecular structure of a CRISPR enzyme that could ...
9-16-2018 F1.large

This natural defense strategy could help some genes fend off CRISPR edits

Sowbugs, armadillos, hedgehogs… and DNA? The same strategy that some animals use to avoid being attacked — roll into a ...
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Viewpoint: What was right and what was wrong with the CRISPR patent decision

The CRISPR patent dispute between the University of California, Berkeley, and the Broad Institute is finally over. … In plain English: Broad researcher ...
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UC Berkeley loses another round in legal dispute with Broad Institute over CRISPR patents

A federal appeals court has rejected arguments that UC Berkeley has exclusive rights to patents for the powerful CRISPR gene-editing ...
9-6-2018 DNA-crispr-cas9-video-real-time_1024

Why some researchers have urged caution with CRISPR gene editing

Despite all the excitement surrounding CRISPR editing, researchers have urged caution about moving too fast. Two recent studies have raised ...
9-6-2018 juan_hunter (1)

In-body gene editing successful in first trial, targeting Hunter syndrome

A therapy that edits genes directly in the human body might be safe, suggest early findings from the first trial ...
CRISPR treatment for dogs with muscular dystrophy could one day lead to a cure for humans

CRISPR treatment for dogs with muscular dystrophy could one day lead to a cure for humans

Dogs suffering from muscular dystrophy are having their genomes edited with CRISPR, and the results are “mind-blowing.” Researchers from Texas ...
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Measuring the risks, potential of CRISPR

The gene editing technology CRISPR has prompted both breathless predictions of medical breakthroughs and warnings of apocalypse. Yale Insights asked ...
8-26-2018 Jennifer Doudna

CRISPR co-creator Jennifer Doudna: Clinical human gene editing 5 to 10 years away

A pioneer of the Crispr gene-editing technology that’s taken Wall Street by storm says the field is probably five to 10 years ...
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Video: Why gene editing could change the path of human evolution

Most people think the genetics revolution is primarily about healthcare. But what's really at play is the evolutionary trajectory of ...
Base Editing: New CRISPR technique could improve ability to safely edit human embryos

Base Editing: New CRISPR technique could improve ability to safely edit human embryos

A new CRISPR technique could prevent humans from passing on a potentially life-threatening disorder, according to Chinese researchers. An estimated ...
8-14-2018 cancer1517756693

A more modest goal for CRISPR: Making chemotherapy ‘a bit less terrible’ for patients

Ambitious efforts to prevent or beat cancer are important, but we can’t overlook or undervalue the incremental breakthroughs that could ...
8-12-2018 Astronaut_working_on_Mars

Genetically modified astronauts? Why humans may need to be redesigned for deep-space missions

NASA is now preparing for a human mission to Mars, but if our descendants ever shrug off their terrestrial bonds, ...
8-7-2018 shutterstock_693879967-e1519405090166

Viewpoint: Why we shouldn’t be deterred by CRISPR’s ‘rollercoaster year’

Despite spooking investors, new insights into DNA repair and the CRISPR gene-editing system are part and parcel of its progress ...
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Rekindling the debate over using CRISPR to edit human embryos

Facing criticism from fellow scientists, the researcher behind the world’s largest effort to edit human embryos with CRISPR is vowing ...
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When is it ok to edit the genome of a human embryo? Americans have mixed opinions

We’ve reached the point in scientific and technological advancement that editing our own genomes, or those of humans not yet ...
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CRISPR may help pave the way to cross-species organ transplants

Modern transplant technology is already pretty miraculous. Doctors can transfer anything from faces to hands to genitals between patients, keep ...
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Using gene editing to merge an organism’s chromosomes into ‘one giant molecule’

Complex organisms have complex genomes. While bacteria and archaea keep all of their genes on a single loop of DNA, ...
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What is CRISPR? And why should you care?

If you haven’t heard of CRISPR yet, the short explanation goes like this: In the past six years, scientists have ...
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Using CRISPR to map human gene functions

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in ...
7-23-2018 Twilley-phages

How bacterial CRISPR defense systems are defeated by suicidal virus attacks

The natural world abounds with examples of predators that cooperate to take down their prey. And such teamwork also exists ...
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Viewpoint: We’re ‘nowhere close’ to being ready to edit human genomes

Genome meddling to cure diseases is often worth the risk, but nothing else is just yet ...
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‘Morally permissible’: Genetically altered babies get nod from UK ethics panel

The creation of babies whose DNA has been altered to give them what parents perceive to be the best chances ...
7-16-2018 crispr_mutations_copy_1024

Why does CRISPR randomly fail 15% of the time?

The CRISPR gene editing process is known to fail about 15 percent of the time. These random failures have until ...
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‘No reason to panic’: Experts react to study suggesting CRISPR isn’t as precise as we thought

A new study, published in Nature Biotechnology, investigates the use of CRISPR/Cas9 to make simple cuts in DNA in mouse ...