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Video: Talking CRISPR challenges with Jennifer Doudna

Jennifer Doudna, winner of the 2018 Kavli Prize in Nanoscience, talks to Scientific American about what it’s like to work in perhaps the ...
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Curing the common cold? Testing on genetically modified mice is first step towards ‘complete protection’

Scientists think they have found a way to stop the common cold and closely related viruses which can cause paralysis. Instead ...
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Viewpoint: Public supports CRISPR, gene drives to battle infectious disease, plant pests—despite activist opposition

Consumers are less wary of biotechnology when they know how it's being deployed ...
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Gene editing used in China in a failed but promising attempt to cure HIV

Scientists in China have used CRISPR gene-editing technology to treat a patient with HIV, but it didn't cure the patient, ...
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Obesity and diabetes cure? CRISPR might be used to ‘silence’ key gene found in unhealthy fat

The gene FABP4 is highly active in adipose tissue and known to be a major contributor to obesity and related ...
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‘More versatile and less error prone’ SATI gene editing could eventually replace CRISPR

[S]cientists at the Salk Institute have developed a potential game changer in this field – a new gene editor called ...
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‘Permanent fix’ for melanoma, blindness, sickle cell? CRISPR gene editing tackles diseases

In the past 12 months, four clinical trials launched in the United States to use CRISPR to treat and potentially cure patients ...
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‘Huge step’ for synthetic biology: CRISPR upgrade allows editing of larger genome fragments ‘with ease’

Imagine a word processor that allowed you to change letters or words but balked when you tried to cut or ...
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How CRISPR could help eradicate chronic pain

The street performer was only 10 years old. He put knives through his arms and walked on hot embers. By ...
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CRISPR creates ‘smart’ hydrogels that could lead to therapies capable of fighting multiple infections, diseases

Is there anything CRISPR can’t do? Scientists have wielded the gene-editing tool to make scores of genetically modified organisms, as ...
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We can identify ‘bad’ genes. Why can’t we use CRISPR gene editing to get rid of them?

Gene therapy 2.0 using CRISPR to knock out harmful genes sounds is a great idea--if and when it works. But ...
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Gaming for catastrophe: Bioterrorism could create a pathogen ‘far worse than nature ever could’

In the darkened ballroom of the Mandarin Oriental Hotel in Washington, D.C., some of the finest minds in government are ...
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Controversial CRISPR-edited sperm experiment seeks to reduce risk for breast, ovarian, prostate cancers

Reproductive biologists at Weill Cornell Medicine in New York City are attempting to use the powerful gene-editing technique called CRISPR ...
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‘Sputnik 2.0’: China wants to lead the world in CRISPR research

China is seeing an explosion in CRISPR-based animal studies and embracing the gene-editing technology with unrivaled zest and zeal—so much ...
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Answering key questions about CRISPR gene therapies

What is gene editing?  Genome editing (also known as gene editing) is a group of technologies that provide scientists with ...
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CRISPR ‘put to the test’ against inherited blindness, blood disease. Next up Duchenne muscular dystrophy, cystic fibrosis

Since its debut in 2012, CRISPR gene editing has held the promise of curing most of the over 6,000 known ...
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‘We simply don’t yet know enough’: International commission urges caution with human germline editing

Using CRISPR in a heritable way raises the stakes exponentially ...
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We’re unlikely to cure Alzheimer’s with CRISPR. But the gene-editing tool could play a crucial role.

Nearly 6 million Americans live with Alzheimer’s disease without solid treatment options ...
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Are you ‘icked out’ by human-monkey chimeras? Here’s why scientists have taken this controversial step

[July 31], news broke that a prominent stem cell researcher is making human-monkey chimeras in a secretive lab in China ...
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CRISPR moves from the lab to human trials, targeting blindness, beta thalassemia and sickle cell anemia

It’s only been seven years since scientists first learned how to precisely and reliably splice the human genome using a ...
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Rushing to revamp international gene-editing rules before ‘crazy people’ start opening embryo-editing clinics

The second-most shocking thing He Jiankui told the international genome editing summit in Hong Kong last November — right after ...
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‘Don’t try this at home’: New California law targets biohacking, do-it-yourself CRISPR

California wants to make it clear that tinkering with your own genes is a “don’t try this at home” sort ...
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Podcast: Has sickle cell disease met its match in CRISPR gene editing?

Dr. Brenda Eustace, director of discovery research at Vertex, joins plant geneticist Kevin Folta to discuss this promising treatment ...
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Why we may never know the fate—good or bad—of China’s controversial CRISPR babies

Since the gene-edited babies known as Lulu and Nana became international news in November 2018, scientific debate and media speculation ...
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Sickle cell disease targeted with CRISPR therapy as ‘the only potential cure’

[F]or the first time, doctors in the United States used the gene editing tool CRISPR to attempt to remedy a ...
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How a one-time CRISPR shot could obliterate lower back pain

CRISPR may be able to block back pain by dampening the immune system’s cytokine signals ...
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Why China’s willingness to push ethical boundaries with CRISPR research ‘could end up benefiting us all’

Today, [China] serves as the global center for CRISPR animal experiments, with its scientists being the first to use the ...
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Why this attempt to cure an inherited form of blindness with CRISPR is so important

The time has come to see if the promises of CRISPR as a therapeutic tool hold true ...