8-7-2018 shutterstock_693879967-e1519405090166

Viewpoint: Why we shouldn’t be deterred by CRISPR’s ‘rollercoaster year’

Despite spooking investors, new insights into DNA repair and the CRISPR gene-editing system are part and parcel of its progress ...
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Rekindling the debate over using CRISPR to edit human embryos

Facing criticism from fellow scientists, the researcher behind the world’s largest effort to edit human embryos with CRISPR is vowing ...
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When is it ok to edit the genome of a human embryo? Americans have mixed opinions

We’ve reached the point in scientific and technological advancement that editing our own genomes, or those of humans not yet ...
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CRISPR may help pave the way to cross-species organ transplants

Modern transplant technology is already pretty miraculous. Doctors can transfer anything from faces to hands to genitals between patients, keep ...
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Using gene editing to merge an organism’s chromosomes into ‘one giant molecule’

Complex organisms have complex genomes. While bacteria and archaea keep all of their genes on a single loop of DNA, ...
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What is CRISPR? And why should you care?

If you haven’t heard of CRISPR yet, the short explanation goes like this: In the past six years, scientists have ...
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Using CRISPR to map human gene functions

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in ...
7-23-2018 Twilley-phages

How bacterial CRISPR defense systems are defeated by suicidal virus attacks

The natural world abounds with examples of predators that cooperate to take down their prey. And such teamwork also exists ...
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Viewpoint: We’re ‘nowhere close’ to being ready to edit human genomes

Genome meddling to cure diseases is often worth the risk, but nothing else is just yet ...
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‘Morally permissible’: Genetically altered babies get nod from UK ethics panel

The creation of babies whose DNA has been altered to give them what parents perceive to be the best chances ...
7-16-2018 crispr_mutations_copy_1024

Why does CRISPR randomly fail 15% of the time?

The CRISPR gene editing process is known to fail about 15 percent of the time. These random failures have until ...
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‘No reason to panic’: Experts react to study suggesting CRISPR isn’t as precise as we thought

A new study, published in Nature Biotechnology, investigates the use of CRISPR/Cas9 to make simple cuts in DNA in mouse ...
Gene drives could speed up inheritance of certain beneficial traits in mammals, study finds

Gene drives could speed up inheritance of certain beneficial traits in mammals, study finds

Researchers have used CRISPR, the genome editing tool, to speed the inheritance of specific genes in mammals for the first ...
Viewpoint: CRISPR gene editing might quell 'frankenfood' fears and win consumer support for biotech

Viewpoint: CRISPR gene editing might quell ‘frankenfood’ fears and win consumer support for biotech

The debate surrounding genetically engineered (“GE” or “GMO”) plants and animals has historically been, and still is, extremely divisive. Anti-GMO ...
'Wake-up call'? CRISPR gene editing may cause 'genetic havoc', study suggests

‘Wake-up call’? CRISPR gene editing may cause ‘genetic havoc’, study suggests

From the earliest days of the CRISPR-Cas9 era, scientists have known that the first step in how it edits genomes — snipping ...
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Viewpoint: ‘Worrisome conflicts’ created by lack of diversity in biotech research funding

You exit a cramped, hazy subway car with a throng of professionals. As you emerge blinking into Kendall Square in ...
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Will Africa embrace CRISPR gene editing and the next phase of the biotech revolution?

Scientists around the world are increasingly turning to the promise of CRISPR gene editing to tackle any number of problems ...
6-28-2018 shutterstock_698068696-750x500

Editing the brain? CRISPR and gold nanoparticles could make it possible

Add this to the list of possible applications for the seemingly-magical gene editing technology CRISPR: helping people with neurological disorders edit ...
Who will CRISPR benefit? How to prevent this life-saving technology from creating gender and geographical disparities

Who will CRISPR benefit? How to prevent this life-saving technology from creating gender and geographical disparities

From cancer to malaria to HIV, CRISPR is set to open up all kinds of dramatic breakthroughs in medicine, as ...
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Resurrecting the northern white rhino and other lost species. But at what cost?

Time has been called on the northern white rhinoceros, but this call is already being challenged. When the last male ...
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Does CRISPR cause unintended mutations? Not in this monkey study

CRISPR is still new, and no one really knows its potential side effects. Does it cause cancer? How about unintended mutations? To get ...
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Predicting the risk of heart disease using CRISPR and stem cells

In our human genome, there are many elusive genetic variants related to medical conditions, but the impact of these variants to ...
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Can we treat autism with CRISPR gene editing?

Scientists have figured how to use a form of the powerful gene-editing tool CRISPR to erase genetic traits normally associated ...
6-20-2018 francis-mojica

Meet Francisco Mojica, the scientist who first discovered CRISPR in a Spanish salt marsh

Professor [Francisco] Mojica grew up near the Mediterranean port of Santa Pola in Spain, a region famous for its salt ...
6-18-2018 Addgene-scientists-negotiating-work-life-balance

Fueling CRISPR: The nonprofit dedicated to sharing ‘bits of useful DNA’

When Feng Zhang was a graduate student in the early 2000s, he helped make a groundbreaking discovery: Light-sensitive proteins from ...
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With gene drives, we could delete’ an entire invasive species. Should we?

In a windowless London basement, behind three sets of locked steel doors and a wall of glass, thousands of Anopheles gambiae mosquitoes cling ...
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Using CRISPR to build a ‘massive library’ of tools to cure genetic disease

In the past few years, [David] Liu’s become one of the most brightly-shining luminaries in the rapidly advancing field of gene ...
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Using CRISPR to block production of HIV in infected cells

Contracting HIV is no longer the death sentence that it was in the 1980s and early 90s. The first cases ...