CRISPR gene editing on the cusp of adding new gene drive tools to control disease-carrying mosquitoes

CRISPR gene editing on the cusp of adding new gene drive tools to control disease-carrying mosquitoes

[D]espite decades of effort, vaccines have, for many [diseases like malaria and dengue], proved tricky to develop. Better, then, to ...
Viewpoint: 'Magic promised by genetically pruning ‘defective’ embryos has fairy-dusted the eyes of even the most intelligent’ — Maybe it’s time to hit the pause button

Viewpoint: ‘Magic promised by genetically pruning ‘defective’ embryos has fairy-dusted the eyes of even the most intelligent’ — Maybe it’s time to hit the pause button

Advances in genetics have been revolutionized in the last few years. First came CRISPR, which can edit single genes, possibly ...
Viewpoint: Patenting human embryo gene editing? Two rival universities push the ethical and legal debate

Viewpoint: Patenting human embryo gene editing? Two rival universities push the ethical and legal debate

Two prominent groups of scientists, and two major American universities, are trying to patent methods for editing human embryos, with ...
Could we cut out cancer genes using CRISPR gene editing?

Could we cut out cancer genes using CRISPR gene editing?

An oncogene is a gene that has the potential to cause cancer. Fusion oncogenes are cancer-causing genes that are made ...
Chronic pain is a pain: How gene editing offers hopeful alternative to addictive opioids

Chronic pain is a pain: How gene editing offers hopeful alternative to addictive opioids

Chronic pain—defined as pain that persists for longer than 12 weeks despite medication or treatment—is estimated to affect some 20 ...
Genomic Cold War? More nations joining the US in using biotechnology to enhance military capabilities

Genomic Cold War? More nations joining the US in using biotechnology to enhance military capabilities

The UK government recently announced an £800 million, taxpayer-funded Advanced Research and Invention Agency (Aria). The brainchild of the British ...
Dangerously high cholesterol? CRISPR gene editing could lower it, tests on monkeys suggest

Dangerously high cholesterol? CRISPR gene editing could lower it, tests on monkeys suggest

A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed ...
‘It would be huge to see my granddaughter’: In an attempt to cure blindness, scientists use CRISPR to edit DNA inside patients' bodies

‘It would be huge to see my granddaughter’: In an attempt to cure blindness, scientists use CRISPR to edit DNA inside patients’ bodies

Carlene Knight would love to do things that most people take for granted, such as read books, drive a car, ...
‘Less water, fertilizer, pesticides and land’? How next-generation soy and corn seeds optimized with CRISPR and AI can increase crop yields while lowering our carbon footprint

‘Less water, fertilizer, pesticides and land’? How next-generation soy and corn seeds optimized with CRISPR and AI can increase crop yields while lowering our carbon footprint

Inari wants to engineer crops that require less water, fertilizer, pesticides and land. The company is focusing on soybeans and ...
The COVID pandemic has changed the future of CRISPR and synthetic biology, says Rahul Dhanda, Sherlock Biosciences CEO

The COVID pandemic has changed the future of CRISPR and synthetic biology, says Rahul Dhanda, Sherlock Biosciences CEO

It’s been a transformative year for synthetic biology and for the world. The COVID-19 pandemic exposed weaknesses in our global ...
Is science finally getting gene therapy right in the effort to fight intractable diseases?

Is science finally getting gene therapy right in the effort to fight intractable diseases?

Over time, researchers have devised a number of ways to manipulate the genetic activity within cells, often by giving them ...
Biofuels, bioplastics and bioremediation: How CRISPR-designed technologies can protect the environment

Biofuels, bioplastics and bioremediation: How CRISPR-designed technologies can protect the environment

Nowadays, scientists can use CRISPR design technologies to protect the environment. Remember, the environment is at the mercy of human ...
Over the next decade, CRISPR and other forms of gene editing could help people with rare disorders — and millions more with heart disease, diabetes, and chronic pain

Over the next decade, CRISPR and other forms of gene editing could help people with rare disorders — and millions more with heart disease, diabetes, and chronic pain

In the next decade, Crispr-Cas9 and other new gene-editing techniques may protect the health [of] millions of people with a ...
Is embryo gene editing a technology we can afford — ethically and morally? Hank Greely address the future in ‘CRISPR People’

Is embryo gene editing a technology we can afford — ethically and morally? Hank Greely address the future in ‘CRISPR People’

The following is an excerpt from Hank Greely’s book CRISPR People. I see no inherent or unmanageable ethical barriers to ...
‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size

‘Wild West of CRISPR’? Ukraine clinic promises to gene edit graying hair, skin quality and breast size

If I had to pick one country that might be the epitome of the ‘Wild West’ of reproductive and genetic ...
Video: Viewpoint — The upside is immense but ‘threats from CRISPR gene editing are too big to ignore’

Video: Viewpoint — The upside is immense but ‘threats from CRISPR gene editing are too big to ignore’

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary technology that gives scientists the ability to alter DNA. On ...
The age of genetically-enhanced children is approaching. Novelist Kazuo Ishiguro imagines a have-and-have not future, and it’s not pleasant

The age of genetically-enhanced children is approaching. Novelist Kazuo Ishiguro imagines a have-and-have not future, and it’s not pleasant

Biotech interventions to help sick children—like gene therapy—are approached with supreme caution. If a treatment has a reasonable chance of ...
400,000 people – that’s how many die from malaria each year. Here’s how gene editing and gene drives could prevent those deaths

400,000 people – that’s how many die from malaria each year. Here’s how gene editing and gene drives could prevent those deaths

The estimated number of malaria deaths stood at 409,000 in 2019. There is an urgent need to find new ways ...
CRISPR can alter an embryo's genes forever. What happens when there are ‘mistakes’?

CRISPR can alter an embryo’s genes forever. What happens when there are ‘mistakes’?

[He Jiankui] made the first genetically modified babies in the history of humankind. After 3.7 billion years of continuous, undisturbed ...
Podcast: Ezra Klein and Walter Isaacson discuss how CRISPR is poised to redirect the future course of evolution

Podcast: Ezra Klein and Walter Isaacson discuss how CRISPR is poised to redirect the future course of evolution

When future generations look back on this moment in history, will they remember the daily political fights — or will ...
How does CRISPR’s ‘on-off switch’ work? How will it revolutionize genetic research and the development of therapies?

How does CRISPR’s ‘on-off switch’ work? How will it revolutionize genetic research and the development of therapies?

[R]esearchers have published perhaps the greatest advance since 2013 – a way to use CRISPR as an on-off switch for ...
CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

CRISPRoff: Gene editing epigenetic method allows researchers to turn most genes in the human genome on and off without altering DNA sequences

Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing scientists to make targeted changes to ...
An ‘off button’ for pain? CRISPR could stop the opioid crisis by tackling chronic pain at the source

An ‘off button’ for pain? CRISPR could stop the opioid crisis by tackling chronic pain at the source

[In 2006, researchers found a family in Pakistan with] mutations in a gene called SCN9A. Two other families in northern ...
Here’s the skinny on the CRISPR patent saga between the Broad Institute and the CVC group

Here’s the skinny on the CRISPR patent saga between the Broad Institute and the CVC group

CRISPR was first reported by Jennifer Doudna and Emmanuelle Charpentier in 2012, as an outgrowth of their work on bacterial ...
CRISPR gene editing roils public discussion over ‘what it means to be disabled’

CRISPR gene editing roils public discussion over ‘what it means to be disabled’

The gene-editing technology CRISPR promises enormous potential as a therapeutic for curing illnesses, including potentially devising new vaccines.  But the ...
Quickly-advancing human embryo research raises prickly ethical questions

Quickly-advancing human embryo research raises prickly ethical questions

Nature published two peer-reviewed papers about generating in vitro, with slightly different methods, “blastoids” or “human blastocyst-like structures”... Notably, none ...
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