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3 promising CRISPR therapies, including one targeting Duchenne Muscular Dystrophy

With dozens of efforts in the making, from premature aging to obesity and developmental brain disorders, here are the frontrunners ...
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Transparency and trust: Is there room for ‘the people’ in the human gene editing debate?

How does excluding the people service the WHO's stated goals of transparency and trust? ...
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Can light-activated CRISPR lead to new treatments for cancer, diabetes?

Engineers are making their mark on biotech’s hottest commodity. Chinese scientists [April 3] reported that they can control the gene editing tool CRISPR-Cas9 with ...
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Viewpoint: Gene-edited kids are no riskier than the non-edited variety

"The introduction of genetic modifications into future generations could have permanent and possibly harmful effects on the species," a group ...
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CRISPR’s challenge: It’s still easier to subtract genes than it is to add them

Almost always, building something is harder than tearing it down. Similarly, knocking in genes poses a greater challenge than knocking ...
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Why Nobel laureate David Baltimore doesn’t support moratorium on CRISPR babies

Some scientists have recently proposed a temporary moratorium on editing that would result in babies that carry heritable changes. … Science ...
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Video: CRISPR pioneer Jennifer Doudna explains Cas-9 gene editing

Prof Jennifer Doudna, one the pioneers of Crispr-Cas9 gene editing, explains how this revolutionary discovery enables precise changes to our ...
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Viewpoint: No, we don’t need a moratorium on germline gene editing

Should researchers put the brakes on genetically engineering babies? Leading scientists and ethicists recently called for a moratorium on clinical applications of germline ...
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Can the RNA editing race challenge the potential of CRISPR’s DNA editing?

RNA, a short-lived cousin to its better-known partner DNA, is the blueprint for protein production in cells. [Biotech entrepreneur Joshua] ...
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Genetically engineered humans: How do we decide when it’s ethical to create them?

Bioethicist Matthew Liao is open to genetic engineering in theory, but he says he was rather horrified to learn that ...
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Is society ready for the changes CRISPR can bring?

Crispr works in almost every animal that scientists have tried, from silkworms to monkeys, and in just about every cell ...
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Gene-editing rock stars: Geneticists set record with 13,200 CRISPR edits of single cell, opening door to ‘radical redesign’ of species

Since its invention, CRISPR has let scientists introduce DNA changes at specific locations in a genome. Often these precise changes ...
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We need a ‘global registry’ of all human gene-editing research, World Health Organization panel says

An influential committee of the World Health Organization said on [March 19] that it would be “irresponsible” to try to ...
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The promise of genetic engineering in medicine could be threatened by ‘bad press’

Because the disorder is caused by a single mutation in a single gene, sickle cell disease has long been seen ...
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When targeting diseases, how worried should we be about CRISPR’s potential for gene-editing errors?

Of all the big, world-remaking bets on the genome-editing tool known as Crispr, perhaps none is more tantalizing than its ...
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Viewpoint: Call for moratorium on heritable gene editing reminds us of gene therapy’s troubled early days

A group of influential scientists have urged that clinical use of CRISPR be put on hold in the wake of ...
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Top CRISPR researchers want global moratorium on heritable gene editing

After the first International Summit on Human Gene Editing in December 2015, a statement was released. The organizers were unanimous ...
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China tightens gene-editing regulations in wake of CRISPR baby scandal

China’s health ministry has issued draft regulations that will restrict the use of gene editing in humans, just three months ...
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Among questions lingering after CRISPR-babies controversy: When will it happen again?

In the three months since He Jiankui announced the birth of twin girls with edited genomes, the questions facing the ...
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CRISPR’s lengthy patent legal battle could finally end—in a tie

Like a couple of heavyweight boxers who just keep slugging it out, the University of California Berkeley (UCB) and the ...
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Gene editing police? World Health Organization may take on the job

Who’s going to police CRISPR? That was the cry of many scientists after news broke at the end of last ...
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‘Genetic crapshoot’: Two studies suggest clinical use of CRISPR hampered by off-target editing

The version of CRISPR whose selling point has been its precision suffers, ironically, from the same shortcoming that has dogged ...
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UN: ‘Unintended consequences’ of CRISPR gene editing among top 5 ’emerging’ environmental concerns

Genetic engineering, the consequences of thawing permafrost soils and the fragmentation of animal and human habitats through gigantic construction projects ...
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Can vaccines be supercharged by CRISPR, creating ‘one-and-done’ virus protection?

Vaccines are risky or ineffective in people with compromised immune systems, they don’t even exist for several viral diseases, and ...
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Lassa epidemic: Nigeria uses CRISPR to get early jump on viral outbreaks

An epidemic of Lassa fever in Nigeria that has killed 69 people this year is on track to be the ...
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Gene from controversial CRISPR baby experiment could deliver new stroke treatment

A widely criticized experiment last year saw a researcher in China delete a gene in twin girls at the embryonic ...
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Why gene editing isn’t ready for treating human disease: It’s not ‘efficient enough’

Gene editing will likely always come with a bit of risk; when you're cutting and pasting DNA in millions of ...
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‘First ever’ human CRISPR trial targets rare beta thalassemia blood disorder

CRISPR, the groundbreaking and controversial gene-editing technique, has been used in a patient with a debilitating blood disease, scientists revealed ...