Rethinking addiction and the brain on drugs

Every day sees a new research article on addiction, be it cocaine, heroin, food or porn. Each one takes a specific angle on how addiction works in the brain. Perhaps it’s a disorder of reward, with drugs hijacking a natural system that is meant to respond to food, sex and friendship.

Possibly addiction is a disorder of learning, where our brains learn bad habits and responses. Maybe we should think of addiction as a combination of an environmental stimulus and vulnerable genes.  Or perhaps it’s an inappropriate response to stress, where bad days trigger a relapse to the cigarette, syringe or bottle.

None of these views are wrong. But none of them are complete, either. Addiction is a disorder of reward, a disorder of learning. It has genetic, epigenetic and environmental influences. It is all of that and more. Addiction is a display of the brain’s astounding ability to change — a feature called plasticity  — and it showcases what we know and don’t yet know about how brains adapt to all that we throw at them.

“A lot of people think addiction is what happens when someone finds a drug to be the most rewarding thing they’ve ever experienced,” says neuroscientist George Koob, director of the National Institute on Alcohol Abuse and Alcoholism in Bethesda, Md. “But drug abuse is not just feeling good about drugs. Your brain is changed when you misuse drugs. It is changed in ways that perpetuate the problem.”

The changes associated with drug use affect how addicts respond to drug cues, like the smell of a cigarette or the sight of a shot of vodka. Drug abuse also changes how other rewards, such as money or food are processed, decreasing their relative value.

Read the full, original story: Addiction showcases the brain’s flexibility

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.noReviewsLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Jul-17-2026-12_42_10-PM
Viewpoint: RFK, Jr. is setting up a panel to compensate people who claim they were injured by a COVID vaccine–no proof needed 
Screenshot-2026-07-01-at-2.49.48-PM
Dr. TikTok and male fertility: Viral claims tout GLP-1 drugs as fertility boosters. What does the science say?
reverse-aging
Rapamycin: Here’s the skinny on the anti-aging pill that increases the lifespan—of mice by 10%
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
vitamin k refuse genai
More and more babies are developing uncontrollable bleeding—linked directly to vaccine deniers' rejection of vitamin K shots
UK scientists support loosening restrictions limiting embryo research
Are we edging closer to precisely, and safely, editing human embryos?
Screenshot-2026-07-17-at-12.55.22-PM
Viewpoint: Is bagged salad a dangerous science experiment? Challenging an online misinformation campaign
ChatGPT-Image-Jun-25-2026-12_23_17-PM
No, Bill Gates did not secretly engineer ticks to promote veganism
ChatGPT-Image-Jul-6-2026-02_25_26-PM
40 million Americans take glucosamine. If you have memory loss, it could accelerate cognitive decline.
Screenshot 2026-07-11 094410
Growing animal muscle and fat cells inside rice grains and calling it beef: One of numerous genetically engineered products shaking up our ecosystem
ma art page image
‘It’s time to have a conversation’: Once adamantly opposed to human gene editing, UK’s The Guardian acknowledges likely benefits
ChatGPT-Image-Jun-17-2026-03_29_08-PM
Viewpoint: What’s the impact of the U.S. abandoning support for global health?
ChatGPT-Image-Jul-9-2026-02_39_22-PM
Viewpoint: Polyphenols or NAD+ supplements to combat aging: No, Gwenyth Paltrow and followers, don’t waste your money.
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.