Will new European Commission president be unfriendly to biotech?

The Juncker Commission has promised to be “more political” than its predecessor, something GMO backers see as a negative development for the approval of genetically modified crops in Europe.

For GMO backers, more politics is bad news in the face of national bans imposed by some member states in reaction to widespread public opposition to GM crops.  At issue is a legislative proposal by the Commission which aims to break the deadlock on GMO approvals in Europe by formally allowing EU countries to opt-out from the Europe-wide approval system. The proposal, which was backed by the EU’s 28 environment ministers in June 2014, gives back “full responsibility” to member states over the cultivation of GMOs on their territory.

“It seems to us absurd that the EU now introduces new rules that will make it even harder to cultivate GM crops. Is there any need to change the legislation after all? Europe has already the most stringent regulatory system in the world,” Goig said.

What’s particularly puzzling to biotech firms is that politicians may still decide to ban GM crops, in spite of positive scientific assessments by the European Food Safety Authority (EFSA) concluding that they are safe for consumption.

“Our opponents know these products are safe. If it is unsafe, why allow it to be imported?,” Goig asked.

Read the full, original article: GMO lobby sees new Juncker Commission as bad news

Missouri’s right-to-farm amendment could protect farmers from new GMO regulations

Missouri voters and interest groups are locked in a battle over the right to farm, as some farmers say they need to secure that right in response to animal rights advocates and others that want to restrict the way their profession is done.

Missouri voters in August approved a measure that would enshrine the right to farm in the state constitution. However, it passed by such a narrow margin, a recount is now underway. Missouri’s secretary of state is expected to announce the results of the recount.

The idea behind Missouri’s amendment is to add another layer of protection against any future attempts to pass laws regulating anything from the use of genetically modified crops to how livestock are raised. A host of new regulations could put them out of business, supporters say. Missouri Farm Bureau president Blake Hurst agreed.

“We’ve seen animal care amendments across the nation,” he said. “Just recently we’ve seen the GMO initiatives in both Oregon and Hawaii that have actually curtailed farmer seed choices.  We’re hoping to forestall any of that in Missouri.”

Read the full, original article: Missouri battles over amendment granting ‘right to farm’

Ugandan finance minister supports biotech bill

The minister of state for Finance in charge of Planning, Matia Kasaija, has refuted claims  that government has withdrawn the National Biotechnology and Bio safety Bill, 2012 (BSBT). He said government fully supports the Bill. A Bill whose objective includes providing for development and general release of Genetically Modified Organisms (GMOs) in Uganda was tabled in Parliament for the first reading last year by Ajuri county MP Denis Hamson Obua.

Kasaija revealed what he called the government position: “Government has not withdrawn the BSBT 2012 Bill saying the NRM caucus had already discussed and considered the bill, but still wanted the input of other stakeholders, particularly critics.”

Committee chairperson Anthony Semmuli said BSBT Bill, 2012, if passed into law will provide for a regulatory framework to facilitate safe development and application of biotechnology.” He stressed that once passed into law, the Bill would boost food production through the use of improved, drought and disease-resistant seeds and other planting materials. If it is approved by parliament, Uganda would join Rwanda and Kenya, among other countries that have already passed BSBT laws.

Read the full, original article: GMO Bill not withdrawn – Minister

Early autism interventions, before 12 months, appear effective

Early interventions may be effective at treating the symptoms of autism in very young infants, according to a pilot study in children under 18 months.

Children with autism spectrum disorder (ASD) normally start receiving treatment at about 2 years old or older. This is an improvement on 10 years ago, when children with ASD were unlikely to receive treatment until they were 4 years old or more. But Sally Rogers and Sally Ozonoff at the University of California, Davis, have sought to intervene even earlier, in infants as young as 6 months old.

In a pilot study, Rogers and Ozonoff taught the parents of seven infants with symptoms of ASD, aged between 6 and 15 months old, how to overcome developmental delays through interactions during play, bathing and diaper-changing.

Two researchers independently used multiple tests and evaluations to distinguish between infants with symptoms of ASD and those who might just be developing more slowly than average. “These were very symptomatic infants,” says Rogers. “In general these babies did not use their bodies, faces or voices to send and receive messages from their caregivers on what they liked or didn’t like, or wanted more or less of.”

Six of the infants began to show accelerated development by 18 months of age, and by the time they were 3 years old, their development was in the normal range, says Rogers. In contrast, four infants who qualified for the study but whose parents chose not to participate continued to show a worsening of ASD symptoms.

Read the full, original story: Early autism intervention speeds infant development

Maui locals sue in attempt to stop anti-GMO voter initiative

A group of Maui County residents and organizations are suing in an attempt to stop a county voter initiative to ban GMO farming from appearing on the November ballot.

The Molokai Chamber of Commerce and a group called Citizens Against the Maui County Farming Ban filed the lawsuit in 2nd Circuit Court along with seven individuals.

The defendants include Maui County Clerk Danny Mateo and Hawaii Office of Elections Chief Scott Nago. Rex Quidilla, spokesman for the state Office of Elections, said the agency had no comment on pending litigation. Mateo could not be reached for comment.

Citizens Against the Maui County Farming Ban has been flooding the airwaves to convince voters to reject the ban. Now, their lawsuit alleges the title of the initiative — “Genetically Engineered Organisms” — is “deceptive and misleading, and if allowed to remain, would prevent the electorate from casting informed ballots.”

Read the full, original article: Lawsuit seeks to remove GMO voter initiative from Maui County Ballot

Eye disease patient to be first treated with adult stem cells

A Japanese patient with a debilitating eye disease is about to become the first person to be treated with induced pluripotent stem cells, which have generated enthusiastic expectations and earned their inventor a Nobel Prize.

A health-ministry committee has vetted researchers’ safety tests and cleared the team to begin the experimental procedure.

Masayo Takahashi, an ophthalmologist at the RIKEN Center for Developmental Biology (CDB) in Kobe, has been using induced pluripotent stem (iPS) cells to prepare a treatment for age-related macular degeneration. Unlike embryonic stem cells, iPS cells are produced from adult cells, so they can be genetically tailored to each recipient. They are capable of becoming any cell type in the body, and have the potential to treat a wide range of diseases. The CDB trial will be the first opportunity for the technology to prove its clinical value.

Takahashi took skin cells from people with the disease and converted them to iPS cells. She then coaxed these cells to become retinal pigment epithelium cells, and then to grow into thin sheets that can be transplanted to the damaged retina.

Read the full, original story: Next-generation stem cells cleared for human trial

Modern foods genetically modified for centuries

For the health-conscious, the prevailing wisdom is that natural food is the best food. But no matter what studies of GMOs say, one scientific fact is inescapable: basically none of our dietary staples are natural.

Some 10,000 years ago, our ancestors picked tiny berries, collected bitter plants and hunted sinewy game, because these are the foods that occurred naturally in the wild. Then came agriculture, and with it the eventual realization that farmers could selectively breed animals and plants to be bigger, hardier and easier to manage. Here are just a few of the modern supermarket offerings that we have been genetically modifying for centuries:

Grapefruit

Compared to other foods, grapefruits are relatively new and somewhat bizarre. Created sometime in the 18th century, a grapefruit is a hybrid of an orange and a pummelo. The pink variety came from a color mutation discovered in the early 20th century. Around that time, technology also brought a new, faster way for mutations to occur: deliberate radiation exposure.

By bombarding plants with x-rays, gamma rays and fast neutrons, scientists were able to create thousands of new plant varieties. Two of those are the Star Ruby and Rio Red grapefruit, with modified genes for enhanced color.

Read the full, original article: Sorry hipsters, that organic kale is a genetically modified food 

Addiction: How our genes program our preferences and habits

addiction

It has long since been established that alcohol addiction has a genetic component. For those with one parent who exhibits alcoholism, their risk of a similar condition is about 25 percent.

A new look into a broad panel of genes potentially associated with stress-induced alcoholism has identified 11 genes that are highly predictive of addiction.

“This powerful panel of just 11 genes successfully identified who has problems with alcohol abuse and who does not in tests in three patient populations on two continents, in two ethnicities and in both genders,” said Alexander B. Niculescu, M.D., PhD, the principal investigator and associate professor of psychiatry and medical neuroscience man-drinking-alcoholat the Indiana University School of Medicine.

The authors rightly point out that this latest research isn’t the final conclusion, nor is it exhaustive, but the level of correlation they were able to reliably ascertain with these 11 genes is very promising.

Which leads me to the next question:

Are we destined to be our genes?

So if an individual is found to have the genetic predisposition across these 11 genes and their 66 associated single-nucleotide polymorphisms (SNP variations) that were found to be correlated with addiction, is he or she destined to be or remain addicted? Newer research along the behavioral front seems to indicate that such views are unwarranted, and that we have tremendous control over our genetic destiny. Prefrontal-cortex-by-National-Institute-of-Mental-Health

Rajita Sinha at Yale School of Medicine and her colleagues used functional magnetic resonance imaging (fMRI) on test subjects and found that greater sustained activation in the medial prefrontal cortex was associated with longer durations between ceasing drug use and relapse.

This latest set of genetic finding (the 11 genes and their variants) is extremely promising across the neurobiological research. Sinha herself (following the fMRI study results) opined that “the jury’s still out on what kinds of neurobiological predictors show the best sensitivity and specificity…. We get our glucose levels checked, we get our insulin levels checked. Are there ways of thinking about neurobiological markers and metrics as predictors of behavior?”

The genetic study results add more evidence to buttress this avenue of study. Along similar lines of research, where the brain and behavior and genetics converge, Diana Martinez of Columbia University Medical Center has found with her team that individuals with greater dopamine release in their brain and higher concentrations of a particular dopamine receptor (D2) were more likely to successfully complete cocaine addiction treatment and remain drug-free 6 months later that those with lower levels of dopamine and D2 receptor density. aslide24

Martinez and her team are attempting to see if they can increase D2 receptor concentrations and/or dopamine levels by using gene therapy in mice.

A strand of engineered DNA is inserted via a viral vector and delivered inside of certain cell nuclei. Within the nuclei, these DNA are used to create dopamine receptor (D2) protein. In a small study with these altered mice, those with the increased density of D2 receptors self-administered fewer doses of cocaine than unaltered mice, suggesting further evidence strengthening the dopamine pathway linkage.

Indeed, executive function (self-control) regions as well as the cortico-limbic-stratial axis seems to be inextricably linked in the genetics of addiction, and it could very well be that the 11 genes recently identified are cross-linked with these different brain functions.

Individuals who present with the genetics associated with greater predisposition to addiction, reduced activity in the medial prefrontal cortex and/or fewer dopamine receptors could be identified and receive earlier, targeted therapy to increase their odds of extinguishing their habits or addictions and reducing relapse rates. Behavioral therapy and even simply seeing how one’s brain activates in response to seeing addiction cues (tested using cigarette images) have both been shown effective in reducing alcohol, cigarette, and drug consumption, and reduced cravings. In fact, there is currently a study recruiting to collect more data on just this phenomenon.

Ben Locwin, PhD, MBA is a contributor to the Genetic Literacy Project and is an author of a wide variety of scientific articles for books and magazines. He is also a researcher and consultant for a variety of industries including behavioral and psychological, food and nutrition, pharmaceutical, and academic.

Replication errors a boon for flu virus’ quick mutations

Scientists have demonstrated that the influenza A virus makes use of its error-prone genetic replication to increase diversity, thereby facilitating viral survival under different selection pressures. This research has been published in Nature Communications.

“Influenza virus relies on its own enzymes (RNA polymerase) to copy its genetic information during multiplication. The RNA polymerase is error-prone and makes random errors (mutations) during genome replication,” explained lead author Dr. Yen Hui-ling, assistant professor of School of Public Health at the University of Hong Kong (HKU).

Replication errors lead to the generation of a progeny viral population with minor genetic differences from each other. This genetic diversity is also termed “quasispecies” and it is believed to be an important strategy for RNA viruses to survive under selection pressures, such as host immune responses. However, it has been challenging to provide experimental proof for the role of “quasispecies” in RNA virus survival. This concept was first experimentally demonstrated using poliovirus but has not been studied for influenza virus to date.

Read the full, original story: How influenza uses random errors to survive

How will evolution and technology interact in the future of the human species?

Will our bodies evolve to eliminate age-related diseases or will we use technology to change our bodies before that happens? Will new species of hominids develop?

Scientific American asked leading scientists how they think humans will evolve in the future. Here is what they had to say. For more expert commentary, go to ScientificAmerican.com/sep2014/predictions

See the full infographic: Where is human evolution taking us?

All tumors should be genotyped. Why aren’t they?

There are huge benefits to genomic tumor assessment, both for better treatment now, and later, if first-line treatments fail. But I don’t think many cancer patients—and even some physicians—fully understand how important tumor sequencing can be to successful cancer treatment. Yet.

This is not surprising. Outside of a few tests for breast cancer, we really didn’t have the tools to do this sequencing even just five years ago. The first major breakthrough that I saw in clinical practice was for metastatic melanoma, a very rare clinical scenario where the incidence is maybe 10,000 cases a year. Suddenly in August 2011, there was a machine I could put in my lab, and in one day obtain results of a molecular test that had a tremendous impact on treating the patient, according to whether the tumor was BRAF positive or BRAF negative.

From that time on, there has been an increasing number of solid tumors where we can test for a genetic biomarker that indicates a specifically targeted treatment, such as the FDA-approved testing for EGFR in non-small-cell lung cancer and KRAS in colorectal cancer.

One point of controversy is clinical. Clinicians often don’t want too much information early on because it complicates their treatment planning. As a physician, once you know something, you become responsible for that information. It’s great to have a comprehensive test that provides all this detail about the tumor genetics, but the clinician is left having to figure out what this means for treatment. That may just be too much information at a time that’s not helpful, when you just need to implement a treatment plan.

Read the full, original story: Why the controversy? Start sequencing tumor genes at diagnosis

Genetics of intelligence: many, many genes with tiny effects

Albert Einstein Head

With the exception of the APOE gene and Alzheimer’s disease, the search for genes that control intelligence, cognitive ability and cognitive decline in aging have been largely unfruitful. That’s likely because intelligence is such a complicated human trait. Even the standardized way its measured, in terms of general intelligence, IQ, is quite controversial.

In a recent study, some very big names in the field of neuroscience and genetics published the results of an extremely large study (more than 100,000 international participants) that went looking for genes associated with cognitive performance. They found three. More accurately, they found three single nucleotide polymorphisms (SNPs) that corresponded to intelligence. And in a follow up these proved to be protective against age-related cognitive decline.

But how predictive of intelligence were these three spots on the human genome? Not very. In total the three SNPs accounted for less than 2 IQ points worth of variation in human intelligence, if a person had two copies of all the intelligence-beneficial mutations compared to someone who had none, explains Nature’s Ewan Callaway:

To put those figures in perspective, those variants have about one-twentieth the influence on intelligence as do gene variants linked to other complex traits such as height, says Daniel Benjamin, a social scientist at Cornell University in Ithaca, New York, who co-led the study.

It’s likely that there are thousands of genes with tiny effect on cognitive performance, according to the study authors. And it’s likely to take an analysis of well over 1 million humans, a study 10 times this size, to really identify those loci with certainty.

This study, however, could help point toward the biological mechanisms that underly cognitive performance. The three gene variants identified in this study, for example, are likely regulators or involved in the processes that control neural plasticity, the ability to learn and make memories, two of the authors pointed out in a editorial at the Syndey Morning Herald. That information is worthwhile for studying aging related dementia.

But for those hoping to identify intelligence genes to pass on to their progeny, blogger and geneticist Razib Khan says don’t hold your breath:

Because intelligence is at least moderately heritable, but the causal variants are so diffuse and numerous, the best bet for having a smart child is picking a spouse with a deviated phenotype. Look for smart people to marry.

Meredith Knight is a blogger for Genetic Literacy Project and a freelance science and health writer in Austin, Texas. Follow her @meremereknight.

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Media attacks on GMO critics ‘simplistic, misleading representation’

Impacts of Cloud Computing in Japans Social Media

Hot on the heels of a much publicised article in the New Yorker that set out to attack Vandana Shiva comes another on the Scroll.in website (on September 3). Girish Shahane mounts an attack on Shiva and what he believes to be her false and misleading statements about farmer suicides in India.

According to Shahane, Shiva adopts a non-scientific, ideologically-driven, anti-GMO stance, which is symptomatic of the environmentalist movement. Apparently, this approach rests on a conspiracy theory in which “the bad capitalist corporation dominates everything, corrupts everything.”

The message from Shahane is that anti-GMO campaigners are irrational, are ignoring scientific consensus on GMOs and are letting their conspiracy theories and ideology stand in the way of progress; if the likes of Shiva and others of her ilk do not ditch their irrational fears and Mbeki-type anti-capitalist lunacy, we are in danger of turning our backs on the potential wonders of GMOs given to us by Monsanto.

Europeans and their governments have genuine concerns based on science, not phobias about GMOs fuelled by Shiva. It is not science per se that anti-GMO campaigners reject, as Shahane would like us all to believe, but the use and distortion of science for commercial gain. If anything, it is the pro-GMO lobby that appears to have scant regard for science.

Shahane’s view constitutes a simplistic and misleading representation of those who are concerned about GMOs. He constructs his own straw man position of what he perceives anti-GMO campaigners to be so he can then proceed to knock it down. In doing so he displays his own irrationalism, ideology and lack of informed insight into the issues.

Read the full, original article: Media attacks directed against the critics of biotechnology and genetically modified agriculture

Oregon GMO labeling backers open new campaign office, focus on door-to-door canvassing

Oregon is gearing up for a high-profile food fight this election season: a November vote on whether to require food makers to label products containing genetically modified organisms.

The campaigns on both sides of the issue are expected to spend millions of dollars on ad blitzes over the next two months, as was done for similar labeling proposals in California and Washington in 2012 and 2013, respectively — both of which were narrowly defeated.

Backers of Measure 92 were in Eugene on Wednesday to open a new campaign field office. The campaign is also operating offices in Portland and Medford. Campaign spokesman Kevin Glenn said proponents are hoping to do more door-to-door canvassing in Oregon than was done for the Washington and California initiatives.

Colin Cochran, a spokesman for the “No on 92” campaign, said that while Oregonians have a right to know what’s in their food, Measure 92 won’t provide that certainty. For example, under the measure, new labels wouldn’t be required for meat or dairy products from animals that have been fed GMO plants, he said.

But labels would be needed for sugar products that, after processing, don’t contain any of the genetically modified sugar beet plants they were made from. Cochran said existing national standards for organic and non-GMO labels on food products are a “much more reliable” source of information for consumers who want to avoid genetically engineered foods.

Read the full, original article: Advocates dish out details on GMOs

Sperm contains dad’s lifestyle information alongside basic genetic material

lifestyle causes of low sperm count

Since I’m a guy, this may sound weird, but I’ve always found sperm to be pretty boring as cells.

You know the drill. All of our cells contain 23 pairs of chromosomes, except for eggs and sperm; they contain one of each pair, joining forces at fertilization.

Compared with eggs, sperm have an unexciting role in this process. For starters, they have almost no mitochondria, the powerhouses of the cell. But mitochondria also contain DNA, genes of their own. Thus, essentially, all “mitochondrial DNA” is inherited from the female.

Moreover, in an egg (and other nonsperm cells), frenzied activity goes on around the DNA, as proteins called transcription factors turn genes on and off, and as gene products go through quality control, with things called micro-RNAs acting as a filter. But in sperm, dogma holds that genes are inactive; a sperm is just an inert delivery system. It might as well be an Amazon drone delivering 23 unpaired socks.

In other words, while environment rarely changes the DNA sequence of a gene (i.e., a “mutation”), it can cause epigenetic changes in the gene’s regulation. And if that occurs in an egg, such epigenetic markers can be passed to offspring, resulting in “nongenetic transmission of traits.” There can be mother-to-child nongenetic transmission of traits related to the normal workings of the body, behavior and propensities toward certain diseases.

What’s interesting about this? Well, for one thing, it demonstrates further how the environment can alter biology with multigenerational influences. But more specifically, sperm, and the lifestyles of the organisms that make them, play a larger role in these processes than previously thought.

Read the full, original story: Sperm can carry dad’s stress as well as genes

DC nonprofit donates $78,000 to Vermont’s GMO labeling law fund

Vermont has raised more than $300,000 in private donations since May to help defend its GMO labeling law in federal court. SumOfUs, a nonprofit issue advocacy organization headquartered in Washington, D.C., made the largest donation — $78,000 — to a defense fund to help the state pay its legal bills.

The state has received more than 1,000 private donations to defend its labeling law, Act 120, according to the state Department of Finance and Management. State officials estimate it could cost as much as $8 million to defend the law. The Colorado-based Mexican restaurant chain, Chipotle Mexican Grill Inc., donated $50,000 last week. The Vermont ice cream company Ben & Jerry’s also donated $5,000 through the sale of “Food Fight Fudge Brownie” ice cream. Other high profile donors include liberal advocacy group MoveOn.org and the private foundation Ceres Trust — each donated about $50,000.

SumOfUs has more than 5 million members worldwide and is seeking up to 50,000 donors to support Vermont’s labeling law. The donations range up to $500 or more, and the group has received more than 22,000 donations, according to its website. The group also supports a host of other causes, including environmental, labor and animal rights issues.

Read the full, original article: State receives $78,000 check for GMO defense fund

Vietnam green-lights first GM corn crop cultivation but ‘disturbing questions’ remain

Vietnam has green-lighted the cultivation of its first genetically modified (GM) corn crop after leaving a number of disturbing questions unanswered.

“I want to ask the agriculture minister what benefits genetically modified organisms will bring to Vietnamese farmers,” said To Van Truong, a senior scientist at the Ministry of Technology and Science who insists that local corn can out-produce the imported varietals by over 30 percent.

Critics like Truong say Vietnam rolled out the red carpet for foreign biotech giants looking to peddle genetically modified (GM) corn while sidelining dissenting voices like his.

In August, the Ministry of Agriculture and Rural Development approved the imports of four corn varieties engineered for food and animal feed processing—namely, MON 89034 and NK603 , produced by DeKalb Vietnam (a subsidiary of US mega-corporation Monsanto) and Bt 11 and MIR 162 from the Swiss firm Syngenta.

Truong, a vocal critic of GMOs, confirmed that since the agriculture ministry licensed the four GM corn varieties, there has been a “silence” from those who object to the controversial crops.

“Anti-GMO activists now see no point in continuing to debate GMOs; the dice has already been cast,” Truong told Thanh Nien News. “They don’t want to fight tooth and nail against powerful interest groups.”

Read the full, original article: Vietnam to plant genetically modified corn as questions linger

29-year study of trillions of meals shows GE crops do not harm food-producing animals, humans

gm animal feed

Although there have been more than two thousand studies documenting that GMOs do not pose an unusual threat to human health, questions about the safety of genetically modified foods remain in the minds of many consumers.

Gilles-Eric Séralini, in his retracted GMO corn study (later republished in a pay for play journal without peer review), claimed rats fed genetically engineered corn developed grotesque cancerous tumors—the kind no farmer would miss among his animals if the cause-effect was genuinely in place.

Anti-GMO crusader Jeffrey Smith, on his personal website, the Institute for Responsible Technology, lists more than a dozen cases in which he claims test animals fed GMOs exhibited abnormal conditions, including cancer and early death. He also references his own self-published book and anecdotal activist web site posts in claiming that pigs fed GM feed turned sterile or had false pregnancies and sheep that grazed on BT cotton plants often died.

“Nearly every independent animal feeding safety study on GM foods shows adverse or unexplained effects,” he writes. “But we were not supposed to know about these problems either—the biotech industry works overtime to try to hide them. Industry studies described above, for example, are neither peer-reviewed nor published.”

The American Academy of Environmental Medicine—an alternative medicine group that rejects GMOs and believes that vaccines are dangerous, and characterized as a “questionable organization” by Quack Watch and Science Based Medicine—claims, “Several animal studies indicate serious health risks associated with GM food,” including infertility, immune problems, accelerated aging, faulty insulin regulation, and changes in major organs and the gastrointestinal system.”

Leveraging these allegations, anti-GMO groups regularly post blogs alleging that animals fed GMOs have developed health problems that could show up in humans. “Monsanto’s GMO Feed Creates Horrific Physical Ailments in Animals,” screamed a typical headline, in AlterNet, a popular fringe alternative site. It touted “new research” but as is typical of many such articles, it neither cited a study nor linked to any independent research.

Is there any basis to these allegations? After all, globally, food-producing animals consume 70 percent to 90 percent of genetically engineered (GE) crop biomass, mostly corn and soybean. In the United States alone, animal agriculture produces over 9 billion food-producing animals annually, and more than 95 percent of these animals consume feed containing GE ingredients. The numbers are similar in large GMO producing countries with a large agricultural sector, such as Brazil and Argentina.

Estimates of the numbers of meals consumed by feed animals since the introduction of GM crops 18 years ago would be well into the trillions. By common sense alone, if GE feed were causing unusual problems among livestock, farmers would have noticed. Dead and sick animals would literally litter farms around the world. Yet there are no anecdotal reports of such mass health problems.

But we don’t need to depend on anecdotes to address these concerns. Writing in the Journal of Animal Science [NOTE: article behind paywall], in the largest study ever conducted, Alison Van Eenennaam and Amy E. Young, geneticists with the Department of Animal Science at the University of California-Davis, reviewed 29 years of livestock productivity and health data from both before and after the introduction of GE animal feed. The field data represented more than 100 billion animals.

What did they find?

There were no indications of any unusual trends in the health of animals since 1996 when GMO crops were first harvested. Considering the size of the dataset, it can reasonably be said that the debate over the impact of GE feed on animal health is closed: there is zero extraordinary impact.

The authors also address the implications of their study on human health.

No study has revealed any differences in the nutritional profile of animal products derived from GE-fed animals. Because DNA and protein are normal components of the diet that are digested, there are no detectable or reliably quantifiable traces of GE components in milk, meat, and eggs following consumption of GE feed.

The authors go on to warn about the fractured regulatory process in which countries eager to export “second generation” GE crops are likely to get approvals before import countries give their okay to receive the new varieties.

“GE crops with altered output traits for improved livestock feed [are] in the development and regulatory pipeline,” they write. “Additionally, advanced techniques to affect targeted genome modifications are emerging, and it is not clear whether these will be encompassed by the current GE process-based trigger for regulatory oversight.”

They argue for the harmonization of both regulatory frameworks for GE crops and governance of advanced breeding techniques to prevent widespread disruptions in international trade of livestock feedstuffs in the future.

Jon Entine, executive director of the Genetic Literacy Project, is a senior fellow at the World Food Center, Institute for Food and Agricultural Literacy, University of California-Davis. Follow @JonEntine on Twitter

New Cornell project to strengthen voice for science and depolarize debate around GMOs

A new international effort led by Cornell will seek to add a stronger voice for science and depolarize the charged debate around agricultural biotechnology and genetically modified organisms (GMOs).

Supported by a $5.6 million grant from the Bill & Melinda Gates Foundation, the Cornell Alliance for Science will help inform decision-makers and consumers through an online information portal and training programs to help researchers and stakeholders effectively communicate the potential impacts of agricultural technology and how such technology works.

The project will involve developing multimedia resources, including videos of farmers from around the world documenting their struggles to deal with pests, diseases, crop failure and the limited resources available in the face of poverty and climate change.

“Like elsewhere in the world, African scientists still find it challenging to effectively inform the public about their work and its relevance to society,” said Barbara M. Zawedde, coordinator of the Uganda Biosciences Information Center at the National Agricultural Research Organization. “Our effective communication will enable African farmers and citizens to exercise their sovereign right of informed decisions on whether to adopt certain crops and technologies depending on their needs and priorities.”

Read the full, original article: New effort seeks to strengthen voice for science for GMOs