Synthetic gene circuit curbs obesity in mice

Scientists have created a “synthetic gene circuit” to control appetite and prevent obesity.

Laboratory mice were implanted with genetically engineered cells that release an appetite-suppressing hormone. The amount of the hormone, pramlintide, produced varied according to how much fat was in their blood.

Treated animals showed significant reductions in food consumptions, blood fat levels, and body weight when put on a high fat diet.

Read the full, original story here: ‘Gene circuits’ give obesity hope

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