Can aggressive cancer cells be transformed into ‘harmless fat’?

1-24-2019 unnamed file11
Image credit: Farmweek

Imagine if you could turn aggressive cancer cells into harmless fat.

Scientists in Switzerland say they’ve done just that, in a new study in mice. By taking advantage of the “plasticity,” or adaptability, of certain cancer cells during metastasis, the researchers were able to coax breast cancer cells in mice into becoming fat cells.

The scientists accomplished this using a combination of two drugs, both of which are already approved for use in humans by the U.S. Food and Drug Administration (FDA). The treatment didn’t convert all of the cancer cells into fat cells, but it did stop the cancer’s metastasis, or spread to other parts of the body, the researchers said.

Related article:  Promising cancer-fighting tactic—using nanoparticles—runs into a potential glitch

The work is very preliminary, and it’s unclear if the findings will apply to people or to other types of cancers. But because the study used two drugs already approved by the FDA, it “may be possible” that the findings also apply to humans, the researchers wrote in their paper, published [January 14] in the journal Cancer Cell.

If future studies confirm the new work, the researchers believe that the therapy could be used in combination with conventional chemotherapy “to suppress both primary tumor growth and the formation of deadly metastases,” senior study author Gerhard Christofori.

Read full, original post: Cancer Cells Transformed into Harmless Fat in Mouse Study

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Infographic: The evolutionary history of the COVID-19 coronavirus

Infographic: The evolutionary history of the COVID-19 coronavirus

Reuters analysed over 185,000 genome samples from the Global Initiative on Sharing All influenza Data (GISAID), the largest database of ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
glp menu logo outlined

Newsletter Subscription

Optional. Mail on special occasions.
Send this to a friend