The GLP is committed to full transparency. Download and review our Annual Report.

How pink bollworm may evolve resistance to GMO Bt crops

| May 24, 2019

Insect resistant Bt crops are widely grown in many countries all over the world to prevent pest attacks in highly economical crops. However, the ability of pests to rapidly evolve resistance reduces the efficacy of Bt crops. In an article published by Scientific Reports, scientists from Hubei Academy of Agricultural Sciences and Chinese Academy of Agricultural Sciences reported that transposon insertion causes cadherin mis-splicing and confers resistance to Bt cotton in pink bollworm, a devastating pest of cotton globally.

The researchers found the allele (r15) harboring the insertion in a field population from China. They described the insertion as a miniature inverted repeat transposable element (MITE) with two additional transposons and produces two mis-spliced transcript variants. A strain homozygous for r15 had 290-fold resistance to Cry1Ac, little or no cross-resistance to Cry2Ab, and completed its life cycle on Bt cotton producing Cry1Ac. The researchers also reported that for transformed insect cells, susceptibility to Cry1Ac was higher for cells producing the wild-type cadherin than for cells producing the r15 mutant proteins.

Related article:  Confused about the USDA's bioengineered food labels? Here's everything you need to know

The similar resistance of pink bollworm to Cry1Ac in laboratory- and field-selected insects from China, India and the U.S. provides a basis for developing international resistance management practices.

Read full, original article: Crop Biotech Update, May 22, 2019

The GLP aggregated and excerpted this article to reflect the diversity of news, opinion, and analysis. Click the link above to read the full, original article.
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.

Send this to a friend