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Single gene has major impact on gaits in horses and in mice

| September 4, 2012
This article or excerpt is included in the GLP’s daily curated selection of ideologically diverse news, opinion and analysis of biotechnology innovation.

Researchers at Uppsala University, Swedish University of Agricultural Sciences and their international collaborators have discovered a mutation in a single gene in horses that is critical for the ability to perform ambling gaits, for pacing and that has a major effect on performance in harness racing. Experiments on this gene in mice have led to fundamental new knowledge about the neural circuits that control leg movements. The study is a breakthrough for our understanding of spinal cord neuronal circuitry and its control of locomotion in vertebrates.

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