So promising were the births of four macaque monkeys following the therapy in 2009, and results of early-stage human embryonic experiments in 2010, that the UK government has announced that the necessary steps to regulate the procedure will be debated in Parliament next year.
But the push toward the clinic may be premature, a group of biologists write in a paper published this week. They worry that the mtDNA from the donor might be incompatible with the nuclear DNA from the parents, and cite a number of animal studies that indicate the treatment can profoundly change the expression of nuclear genes and affect cognition, lifespan and fertility, especially in males.
Read the full, original story here: Warning sounded over three-parent IVF safety
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