‘Paleo’ diet out of step with human evolution

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis.

The article kicked off not just a diet, but a movement. Appearing in the New England Journal of Medicine in January 1985, “Paleolithic Nutrition: A Consideration of Its Nature and Current Implications” argued that the human body is “genetically programmed” to run, not on a modern diet, but on the foods consumed by our Stone Age ancestors.

The authors reasoned that human bodies have been shaped more by our prolonged time as hunter-gatherers than by the brief span since the advent of farming. Meat, probably lots of it, as well as fruits and vegetables were in. The staples of agriculture — breads, cereals, milks and cheeses — were not.

But even as the “caveman” diet rose to become the most Googled diet in 2013 and 2014, evolutionary biologists, with much less advertisement, were using advanced DNA techniques, sometimes on ancient bones, to suggest that the original Paleo premise may be off the mark: In fact, it seems, we have evolved.

Two relatively recent gene variants help humans survive with deficiencies characteristic of agricultural diets; another genetic shift appears to help fight the dental cavities that arose with farm-based staples; another changes the way humans digest fats; dozens of others help fight the diseases that came with living at higher densities.

Those new findings add to previously known adaptations to mankind’s changing diet. After the domestication of milking animals, many humans evolved to digest milk. Humans also appear to have developed better ways to digest the starches characteristic of agricultural diets.

Read full, original post: What actual ‘caveman’ DNA says about the Paleo movement

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.noReviewsLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

Picture1
Hiroshima at 81: America’s new nuclear bomb, a buried Iranian target, and a question no one wants to ask
ChatGPT Image Jul 29, 2026, 05_50_04 PM
Fear, science, and the law: If talc powder is unlikely to cause cancer and J&J was winning in court, why did it pay more than $5.5 billion to settle?
ChatGPT Image Jul 29, 2026, 10_14_27 PM
After muzzling RFK, Jr. over autism-vaccine conspiracy theories, Trump defies aides to push scares again
Screenshot 2026-07-29 at 1.03
Two food fads that have some merit: Chia seeds in almost everything and protein added to water
ChatGPT Image Jul 29, 2026, 06_26_01 PM 2
Facts & Fallacies podcast: Organic food myths make a comeback on Instagram, with Dr. Kevin Folta
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
Screenshot-2026-07-09-at-1.09.25-PM
Anti-vaccine myths rattle health care
ChatGPT Image Jul 29, 2026, 10_31_48 PM
Bowing to Congressional pressure, Kennedy reverses himself and releases $600 million that helps developing countries buy and distribute vaccines
Screenshot 2026-07-28 at 3.43
Fat cat? GLP-1 weight loss drugs for animals are on the horizon
Screenshot 2026-07-28 at 3.22
Hidden hunger: Climate change is speeding up the decline of important nutrients in our food
Screenshot 2026-07-22 at 1.38
Viewpoint: Are the U.S. and Europe headed towards a repudiation of agricultural biotechnology red tape?
organic scaled
Facts & Fallacies podcast: Organic food cuts pesticide exposure? A response to Dr. Rhonda Patrick
ChatGPT-Image-Jul-10-2026-09_42_12-AM-1
Peptides, patient autonomy, and the limits of medical freedom
Screenshot 2026-07-27 at 6.15
No test, no tennis: Women’s Tennis Association becomes first major female sports league to require genetic sex testing
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.