Heart attack memory may be stored on genes via epigenetic changes

heart
Decellularized pig heart.

The memory of a heart attack gets stored in genes through epigenetic changes — chemical modifications of DNA that turns our genes on or off, a study has found.

“During a heart attack the body signals by activating certain genes. This mechanism protects the tissue during the acute phase of the disease…and restores the body after the heart attack. It is therefore likely that epigenetic changes are also associated a heart attack”, said Asa Johansson….

The results of the study showed that there are many epigenetic changes in individuals who had experienced a heart attack.

However, it was not possible to determine whether these differences had contributed to the development of the disease, or if they live on as a memory of gene activation associated with the heart attack, the researchers said.

“We hope that our new results should contribute to increasing the knowledge of the importance of epigenetic in the clinical picture of a heart attack, which in the long run could lead to better drugs and treatments,” Johansson added.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Read full, original post: Memory of a heart attack gets stored in genes: Study

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