Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient’s own stem cells showed that the therapy appears to dampen the body’s neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).
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“The data derived from this trial moves beyond just testing safety of this approach,” said Charles S. Cox, Jr., principal investigator at UTHealth.
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According to the Centers for Disease Control, 1.7 million Americans sustain a traumatic brain injury annually.
Of those, 275,000 are hospitalized and 52,000 die. TBI is a contributing factor to a third of all injury-related deaths in the country.
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The theory is that the stem cells work in the brain to alleviate the body’s inflammatory response to the trauma.
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According to the authors, despite the treatment group having greater injury severity, there was structural preservation of critical regions of interest that correlated with functional outcomes and key inflammatory cytokines were down-regulated after bone marrow cell infusion.
The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: Stem cell therapy may help treat traumatic brain injury (TBI)
