Having trouble conceiving? A new genetic test might help

| | August 7, 2017
Thomas van Ardenne
Credit: Thomas van Ardenne / Flickr
This article or excerpt is included in the GLP’s daily curated selection of ideologically diverse news, opinion and analysis of biotechnology innovation.

More than 50 doctors have already ordered [the Fertilome testfor hundreds of women seeking scientific guidance on questions such as whether they should freeze their eggs for future use, or whether it’s worth it to try another round of in vitro fertilization.

Some reproductive specialists are enthusiastic. But others caution that Fertilome is just the latest genetic test promising more than it can deliver — and, in this case, playing to the fears of women who are anxious about becoming a mother.

The Fertilome test, which must be ordered by a doctor, analyzes a woman’s DNA for 49 genetic variants that have been linked to various conditions that can sometimes cause fertility problems.

A patient may see a table showing that her genetic variants make her twice as likely to have a condition known as recurrent pregnancy loss, defined as repeated miscarriages. But the report doesn’t note that just 1 percent of women have that condition in the first place, making the odds still overwhelmingly in her favor.

“Some of this can be very misleading and very frightening to patients,” said Dr. John Petrozza, chief of the division of reproductive medicine at Massachusetts General Hospital.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: Can a genetic test really boost your odds of becoming pregnant?

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