How DNA can be manipulated to recreate the Mona Lisa

dims

Researchers from Caltech have developed an inexpensive, facile technique for creating very large self-assembling DNA origami structures with customisable patterns. The work, published in Nature [December 6], is the first time that DNA origami has been used to build such large structures and provides other researchers with a relatively simple method for creating their own. The team demonstrated the success of their technique by using it to recreate Leonardo da Vinci’s iconic Mona Lisa painting.

DNA origami was a technique that was originally developed in 2006 and involves combining one long strand of DNA with many smaller one, to fold the complex into a predetermined shape. The smaller DNA fragments, known as staples, bind to specific regions of the long strand, as determined by Watson and Crick DNA binding pairs, and pull the long strand into a specific conformation. This single structure is known as a DNA origami ‘tile.’ Each tile is very small, but multiple tiles can be bound together into a larger structure like a mosaic.

“Other researchers have previously worked on attaching diverse molecules such as polymers, proteins, and nanoparticles to much smaller DNA canvases for the purpose of building electronic circuits with tiny features, fabricating advanced materials, or studying the interactions between chemicals or biomolecules,” said [researcher Philip] Petersen. “Our work gives them an even larger canvas to draw upon.”

Read full, original post: Reproducing Works of Art with DNA Origami

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
Video: Test everyone – Slovakia goes its own way to control COVID

Video: Test everyone – Slovakia goes its own way to control COVID

As Europe sees record coronavirus cases and deaths, Slovakia is testing its entire adult population. WSJ's Drew Hinshaw explains how ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend