What’s it like being in a Phase 3 coronavirus vaccine trial?

Credit: Siphiwe Sibeko/Reuters
Credit: Siphiwe Sibeko/Reuters

I’m at St George’s for an initial screening as a volunteer in the Oxford University trial to test the ChAdOx1 nCoV-19 vaccine. In the coming weeks, I will learn what it is like to be a participant in one of the world’s most promising efforts to tackle to the coronavirus pandemic. Of all the vaccine trials ongoing around the world, the Oxford effort is ahead of most of the pack.

A few weeks later, on 20 July, the researchers would announce extremely promising initial results, based on the first 1,077 people, suggesting that the vaccine is both safe and triggers an immune response… The next step involves expanding the trial at a higher dose to thousands more people, volunteering at sites across the UK, as well as Brazil and South Africa. This phase of the clinical trials, to test efficacy on a much bigger scale, is what I have signed up for.

Related article:  'Partnership with sunlight': Why staying inside all the time makes us vulnerable to infections
Follow the latest news and policy debates on agricultural biotech and biomedicine? Subscribe to our newsletter.

The sad truth is that a volunteer like me in the UK is less likely to tell the scientists if their vaccine shows efficacy, because for now at least, I am less likely to catch the virus than somebody where the pandemic is spreading through the community. For the greater good, some of the 10,000 volunteers in my stage of the trial will need to encounter this killer.

Read the original post

Outbreak
Outbreak Daily Digest
Biotech Facts & Fallacies
Talking Biotech
Genetics Unzipped
ft covidresponseus feature

Video: Viewpoint: The US wrote the global playbook on the coronavirus and then ignored it

A year ago, the United States was regarded as the country best prepared for a pandemic. Our government had spent ...
mag insects image superjumbo v

Disaster interrupted: Which farming system better preserves insect populations: Organic or conventional?

A three-year run of fragmentary Armageddon-like studies had primed the journalism pumps and settled the media framing about the future ...
dead bee desolate city

Are we facing an ‘Insect Apocalypse’ caused by ‘intensive, industrial’ farming and agricultural chemicals? The media say yes; Science says ‘no’

The media call it the “Insect Apocalypse”. In the past three years, the phrase has become an accepted truth of ...
globalmethanebudget globalcarbonproject cropped x

Infographic: Cows cause climate change? Agriculture scientist says ‘belching bovines’ get too much blame

A recent interview by Caroline Stocks, a UK journalist who writes about food, agriculture and the environment, of air quality ...
organic hillside sweet corn x

Organic v conventional using GMOs: Which is the more sustainable farming?

Many consumers spend more for organic food to avoid genetically modified products in part because they believe that “industrial agriculture” ...
benjamin franklin x

Are most GMO safety studies funded by industry?

The assertion that biotech companies do the research and the government just signs off on it is false ...
gmo corn field x

Do GMO Bt (insect-resistant) crops pose a threat to human health or the environment?

Bt is a bacterium found organically in the soil. It is extremely effective in repelling or killing target insects but ...
favicon

Environmental Working Group: EWG challenges safety of GMOs, food pesticide residues

Known by some as the "Environmental Worrying Group," EWG lobbies for tighter GMO legislation and famously puts out annual "dirty dozen" list of fruits and ...
m hansen

Michael Hansen: Architect of Consumers Union ongoing anti-GMO campaign

Michael K. Hansen (born 1956) is thought by critics to be the prime mover behind the ongoing campaign against agricultural biotechnology at Consumer Reports. He is an ...
News on human & agricultural genetics and biotechnology delivered to your inbox.
Optional. Mail on special occasions.
Send this to a friend