As vaccine makers pursue the next generation of COVID-19 vaccines, some are working to develop products that wouldn’t require a shot.
Why it matters: Delivering a vaccine through a pill or a nasal spray could make them much easier to administer, especially in places where distribution is challenging — or even for people who just don’t like needles.
San Francisco-based biotech Vaxart is working on a COVID vaccine that would be delivered in an oral tablet.
India’s Bharat Biotech advanced its nasal COVID-19 vaccine candidate into a phase 2 clinical trial earlier this fall.
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Vaxart began enrolling about 100 people in a Phase 2a clinical trial last month and expects to have a readout of that efficacy trial in the first quarter of 2022.
Vaxart’s vaccine showed promise in animal trials, the results of which were published in early October.
What’s next: Even if everything continues to go well, the earliest the company would be able to apply for an emergency use authorization from the FDA is still at least a year to 18 months away — but the world will still need COVID vaccines in a year to 18 months.
