Nanocontraception: How heated nanoparticles injected in testicles might be a viable method of male birth control

Credit: ShutterStock
Credit: ShutterStock

Nanocontraception is based on the idea that nanoparticles — here, about 100 nanometres in diameter, or roughly one-thousandth the width of a piece of paper or of a strand of human hair — can somehow be delivered to the testicles, where they can be warmed.

If you could warm up the testicles just a bit, you would have a way to turn sperm production on and off at will because the warmer they get, the less fertile they become. But it’s a delicate process because the testicles can be irreversibly destroyed if they become too warm; the tissue dies and can no longer produce sperm, even when the testicles return to their normal temperature.

Using nanotechnology to warm testicles was first studied in 2013 on mice by biologist Fei Sun and his multidisciplinary research team. His early experiments involved injecting nanoparticles directly into mouse testicles. 

Mis- and disinformation are distorting science and public policy. Subscribe to our Daily and Weekly Digests for incisive coverage of ‘disruptive’ innovations in AI, agricultural biotechnology, food, chemicals, nuclear energy, vaccines, and other disruptive innovations.

Sun’s ultimate goal is human contraception, although he admits that’s still a long way off. As with zoo animals, detailed studies will be required to establish that nanocontraception is not toxic for men. It is also more difficult to put a man under anesthesia for four hours and wrap an electric coil around his testicles than it is to do the same thing on a mouse.

This is an excerpt. Read the original post here. 

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
AI Doctor with a Digital Neural Head
Utah becomes first state to empower AI to bypass doctors and prescribe certain drugs
Screenshot-2026-09-22-at-12.26.15-PM
‘Forever chemical’ concerns: Separating hysteria from reasonable concern in the debate over PFAS danger
Screenshot-2026-10-07-at-2.00.02-PM
9 wellness myths busted
Screenshot-2026-10-06-at-11.13.59-AM
RFK Jr.’s plan to curb America’s appetite for ultra-processed foods and artificial dyes blocked by the White House
Screenshot 2026-07-29 at 10.40
The COVID vaccine turbo cancer scare is back. Science still proves it’s wrong.
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.