Nootropics: No evidence over-the-counter supplements preserve memory — and they may be dangerous

micobutin capsules and powder
Capsules and powder of rifabutin (Mycobutin). Credit: Wikimedia Commons (CC BY-SA 3.0)

Is there anybody over 50 who wouldn’t want to maintain their cognitive skills and remember where they put their keys? Yes, the market for what are called nootropics is booming as millions of aging individuals long to stay sharp and fight off cognitive decline.

Now, just for the record, there are several well-known and physician-prescribed drugs under the banner of nootropics – stimulants, like Ritalin and Adderall, and synthetic compounds such as piracetam. My focus is what viewers see in the commercials, and what they’ll be drawn to – flashy off-the-shelf enhancements portrayed as wonder drugs.

Follow the latest news and policy debates on sustainable agriculture, biomedicine, and other ‘disruptive’ innovations. Subscribe to our newsletter.

A study published in the journal Neurology Clinical Practive shows that over-the-counter cognitive enhancement supplements may contain multiple drugs unapproved drugs for use in the U.S. The study concludes with a cautionary note: the health effects of ingesting untested combinations and dosages of these drugs absent clinical engagement are unknown.

“There is little hard evidence that these products are either safe or effective for consumers to use,” adds Chuck Bell, programs director for Consumer Reports advocacy division.

And Harvard Medical School, pointing to a survey that about 25% of people over 50 use supplements to improve their brain health, reports that there is no proof that any of them work.

This is an excerpt. Read the original post here

{{ reviewsTotal }}{{ options.labels.singularReviewCountLabel }}
{{ reviewsTotal }}{{ options.labels.pluralReviewCountLabel }}
{{ options.labels.noReviewsLabel }}
{{ options.labels.newReviewButton }}
{{ userData.canReview.message }}

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

ChatGPT-Image-Jul-26-2026-05_58_17-PM
Louisiana and Texas bring RFK,Jr.- MAHA-backed restrictions on dyes and other ‘controversial’ ingredients to eight states
ChatGPT-Image-Jul-26-2026-05_35_53-PM
FDA takes up peptide therapies as hype outpaces science
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
organic scaled
Facts & Fallacies podcast: Organic food cuts pesticide exposure? A response to Dr. Rhonda Patrick
ChatGPT-Image-Jul-22-2026-09_13_07-AM
Viewpoint—The Strategic Litigation boom: Understanding the tightening coalition among NGOs, foundations, journalists, and tort lawyers
ChatGPT-Image-Jul-9-2026-11_33_49-AM
Viewpoint: High-dose resveratrol supplements to extend health and life? Don’t waste your money.
ChatGPT-Image-Jul-10-2026-09_42_12-AM-1
Peptides, patient autonomy, and the limits of medical freedom
Screenshot-2026-07-23-at-11.58.47-AM
Viewpoint: ‘Thought police in the UK?’ Conservatives lash out at government report calling anti-LGBQT+ narratives ‘false and misleading’
How to Include More Strawberries in Your Diet
Strawberries are berries—and 35 other surprising food and drink myths
IVF Rex
Poll: Younger people more open to using genetics to increase fertility and reduce chances of inherited diseases 
Screenshot-2026-07-07-at-12.55.44-PM
Viewpoint: Yes, we can adapt to a changing climate without devastating the environment and the economy
ChatGPT-Image-Jun-25-2026-12_23_17-PM
No, Bill Gates did not secretly engineer ticks to promote veganism
ChatGPT-Image-May-22-2026-10_26_09-AM
Trump-RFK, Jr. National Science Board firings: Accountability vs. partisan meddling
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.