‘Blue leg syndrome’: Yet another long COVID health problem

Credit: Stock Snap (Public Domain)
Credit: Stock Snap (Public Domain)

Media attention turned to a case report in The Lancet detailing how a man’s legs would turn blue after standing for about 10 minutes, which researchers said is likely related to his long COVID.

The 33-year-old man told doctors that for the past 6 months, his legs would feel progressively heavy, tingly, and itchy, and then would become “dusky” in color, according to medical student Nafi Iftekhar and Manoj Sivan, MD, of the Leeds Institute of Rheumatic and Musculoskeletal Medicine at the University of Leeds in England.

In addition, a petechial rash would occasionally appear on his feet, they reported. His legs would return to a normal color and the symptoms would go away when he would lay down.

Iftekhar and Sivan diagnosed the patient with “dysautonomia secondary to SARS-CoV-2 infection and associated with long COVID.”

Mis- and disinformation are distorting science and public policy. Subscribe to our Daily and Weekly Digests for incisive coverage of ‘disruptive’ innovations in AI, agricultural biotechnology, food, chemicals, nuclear energy, vaccines, and other disruptive innovations.

Bruce Hirsch, MD, an infectious disease physician at Northwell Health in Manhasset, New York, noted that the symptom of blue legs “doesn’t seem that different from what we’ve been hearing over the last couple of years, like COVID toes … and we know that the circulation is impacted in many people with the complications of long COVID.”

This is an excerpt. Read the full article here

Related Articles

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Infographic: Global regulatory and health research agencies on whether glyphosate causes cancer

Does glyphosate—the world's most heavily-used herbicide—pose serious harm to humans? Is it carcinogenic? Those issues are of both legal and ...

Most Popular

Screenshot 2026-10-16 at 11.17
Viewpoint: Latest attack on renewable energy and farmers, new USDA rules could put solar grants out of reach for small producers
png_cheese_Raw_milk
100% raw milk, 100% misguided: As MAHA-fueled demand for unpasteurized milk soars, American Academy of Pediatrics renews call for a ban on its sale and distribution
ChatGPT-Image-Mar-10-2026-01_39_01-PM
Viewpoint—“Miracle molecule” debunked: Why acemannan supplements don’t work
Screenshot-2026-10-19-at-11.09.17-AM
Vaccines, religious freedom, and protecting children’s health: New York Amish appeal to Supreme Court after $118,000 in vaccine fines for blocking shots
Golden-GM-Emblem-with-EU-Stars
As Europe inches forward in its embrace of gene-edited crops, hopes abound that opposition to GMOs might fade
Nutrition and Supplements Infinity Collage
Drugs and supplements can extend life and five other longevity myths
ChatGPT-Image-May-28-2026-12_56_54-PM
Viewpoint: Vaccines' non-specific effects? The ‘shoddy’ Danish couple whose 'research’ inspires RFK, Jr.’s health delusion
Screenshot 2026-10-16 at 5.38
PFAS in Agriculture: Science, Uncertainty, and Risk Communication
Screenshot-2026-10-20-at-10.53.36-AM
World Health Organization calls Kennedy- and CDC-backed Guinea-Bissau hepatitis B vaccine study designed to ‘prove’ the danger of vaccines “unethical”
psychedelics ptsd neurosciencnews public
Chaos or at peace with the world: The complex ways psychedelics transform the brain
Serene Mature Woman in Abstract Waves
Testosterone’s growing appeal to women: It anecdotally mildly improves sex life, but are there any other potential benefits—or red flags?
Screenshot 2026-10-19 at 11.19
How the “wellness” movement has turned into a rigid cultural belief system
Mifeprex Boxes and Woman Drinking Water
RFK Jr.’s EPA capitulates to anti-abortionists, authorizes study of safe abortion pills which activists falsely claim are “poisoning” our water supply
glp menu logo outlined

Get news on human & agricultural genetics and biotechnology delivered to your inbox.